Topic
Optical coherence tomography
About: Optical coherence tomography is a research topic. Over the lifetime, 19051 publications have been published within this topic receiving 477433 citations. The topic is also known as: optical coherent tomography.
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TL;DR: In this article, a three-level expert grading scale was used to evaluate the discriminative abilities of signal-to-noise ratio (SNR) and signal strength and macular thickness.
Abstract: Background: As optical coherence tomography (OCT) is widely used for diagnosis and monitoring of ocular pathology, especially in the elderly people, the influence of cataract on image quality and macular retinal thickness was studied. Methods: In 29 patients scheduled for cataract surgery, preoperative and postoperative OCT scans were obtained. Cataracts were categorised as nuclear, posterior or cortical. Parameters for image quality (signal-to-noise ratio (SNR)) and signal strength and macular thickness were compared. A three-level expert grading scale was used to evaluate the discriminative abilities of SNR and signal strength. Results: Nuclear cataracts (n = 12) provided better preoperative scans (higher SNR/signal strength) than posterior (n = 7) and cortical (n = 10) cataracts (p Conclusions: OCT imaging is influenced by cataract; image quality is reduced preoperatively and macular thickness measurements are slightly increased postoperatively. In individual patients, OCT scans remain reliable for gross clinical interpretation, even in the presence of cataract.
113 citations
TL;DR: An algorithm to detect AA in OCTA separated into three individual plexuses using a projection-resolved algorithm accurately distinguishes mild NPDR from control eyes and is highly repeatable.
Abstract: Purpose
The purpose of this study was to evaluate an automated algorithm for detecting avascular area (AA) in optical coherence tomography angiograms (OCTAs) separated into three individual plexuses using a projection-resolved technique.
113 citations
TL;DR: This work presents spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope, and restricts the spatial extent of the signal by using high-numerical-aperture optics makes high-resolutionSpectroscopic information accessible, facilitated with spectral- domain detection.
Abstract: The spectroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells.
113 citations
TL;DR: Time‐domain optical coherence tomography (OCT) is used to measure changes in the crystalline lens with age and accommodation to utilize time‐domain Optical Coherence Tomography for diagnosis of lens disease.
113 citations
TL;DR: There is very good repeatability of corneal thickness measurement using OCT; even the worst case measurements are similar between sessions; on the other hand, this is not the case for epithelium measurements, and if multiple images within a session are acquired, the best case results demonstrate how important it is to optimize each OCT scan and also average multiple scans to maximize intersession repeatability.
Abstract: Purpose.The purpose of this study is to examine within and between session repeatability of clinical optical coherence tomography (OCT) imaging for anterior segment morphometry.Methods.Images of the corneal apex of each eye in 18 subjects were obtained using a Humphrey Zeiss OCT imager. Subj
113 citations