Showing papers on "Organomercury Compounds published in 1998"
TL;DR: In this article, a multicapillary column gas chromatography (MC-GC) was used for fast speciation analysis of organometallic compounds, including butyltin and organomercury compounds in sediment, and of tetraalkyllead compounds in gasoline.
43 citations
TL;DR: In this paper, a method for the structural confirmation of mercury (II) chloride and organomercury (III) chlorides (monomethylmercury chloride, monoethylmercure chloride, and monophenylmer cury chloride) employing liquid chromatography coupled to atmospheric pressure ionization mass spectrometry was developed.
Abstract: A method for the structural confirmation of mercury (II) chloride and organomercury (II) chlorides (monomethylmercury chloride, monoethylmercury chloride and monophenylmercury chloride) employing liquid chromatography coupled to atmospheric pressure ionization mass spectrometry was developed. The chromatographic system comprised a Kromasil 100-5C18, 5μm (250 × 4.6 mm) column and a mobile phase of 2-mercaptoethanol (0.01% v/v) in methanol: water (1:1 v/v), at a flow rate of 1 mL min−1. The optimization of the API-MS conditions is discussed, together with the fragmentation patterns observed for standards. No peaks due to the molecular ion were present and the most intense peaks were due to [M + mercaptoethanol]+ or [M + 2 mercaptoethanol − H]+. The qualitative analysis of fish tissue spiked with methylmercury (II) chloride, using selected ion monitoring (SIM), is discussed. © 1998 LGC (Teddington) Ltd.
24 citations
19 citations
TL;DR: Patch tests revealed that in causing positive reactions to TH, EtHg probably interacted with thiol groups and with Zn ions, as in biological systems when causing toxic effects, and it is speculated that positive subjects have a constitutively reduced capability to metabolize organomercury compounds, rather than to reveal previous exposure.
Abstract: For a better understanding of the mechanistic details of the interactions of organomercury compounds inside the skin, 32 subjects who previously had given positive patch-test reactions to thimerosal (TH) and negative reactions to thiosalicylic acid, were divided into 2 groups. 16 subjects were repatch tested to ethylmercury chloride (EtHgCl) and to solutions containing EtHgCl mixed with L-cysteine and glutathione, respectively. The remaining 16 were repatch tested to EtHgCl and to solutions containing EtHgCl mixed with chlorides of Zn, Mg, and Mn, respectively. The results showed that whilst L-cysteine, glutathione and ZnCl2 were able to abolish or to reduce the positive reactions to EtHgCl, chlorides of Mg and Mn were unable to do so. Patch tests revealed that in causing positive reactions to TH, EtHg probably interacted with thiol groups and with Zn ions, as in biological systems when causing toxic effects. The limited number of TH reactions in the general population, the constant presence of concomitant positive reactions to EtHgCl and MeHgCl, and the lack of cross-reactivity with other organic or inorganic mercury compounds, lead us to speculate that reactions to TH are due to organomercury alkyl compounds, and that positive subjects have a constitutively reduced capability to metabolize organomercury compounds, rather than to reveal previous exposure.
16 citations
TL;DR: In this article, the authors proposed a simple, inexpensive and does not require the preliminary conversion of organomercury compounds to elemental or ionic mercury, which is applied successfully to methylmercury determination in water of Kara Sea.
Abstract: The enzymatic determination of organomercury compounds (methyl-, ethyl-, phenyl-mercury) is based on their effect on the induction period (τind) caused by the introduction of sodium diethyldithiocarbamate to the oxidation of o-dianisidine, o-phenylenediamine and 3, 3′, 5, 5′-tetramethylbenzidine by H2O2 catalysed by native horseradish peroxidase. τind is inversely proportional to organomercury compounds concentration over a range of 0.05–10 μM. The lowest detection limit (Cmin) is 0.03 μM and the standard relative deviation (RSD) is lower than 3%. The proposed method is simple, inexpensive and does not require the preliminary conversion of organomercury compounds to elemental or ionic mercury. The developed procedure is applied successfully to methylmercury determination in water of Kara Sea.
6 citations