Showing papers on "Organomercury Compounds published in 2020"

Synthesis and Molecular Structure Study of New Organotellurium and Organomercury Compounds Based on 4-Bromonaphthalen-1-amine

Abstract: The new organic derivatives of mercury and tellurium have been prepared by a reaction of 4-bromonaphthalen-1-amine with Hg(CH3COO)2 and further with TeBr4. Reaction of (1-amino-4-bromonaphthalen-2-yl)mercury(II) chloride with benzaldehyde then TeBr4 has produced the new aryaltellurium(IV) tribromide containing the azomethine moiety. Reaction of 4-bromo-2-(tribromo-λ4-tellanyl)naphthalen-1-amine with 4-hydroxyphenyl mercury(II) chloride gives asymmetrical diaryaltellurium(IV) dibromide. Reduction of aryaltellurium tribromide and diaryaltellurium dibromide by hydrazine hydrate leads to the corresponding diaryalditelluride and diaryaltullride. Structures of the synthesized compounds have been elucidated from FT-IR, 1H, and 13C NMR spectra. The molecular structures and energies for the compounds were also calculated according to the DFT concept.

Mercuration and Telluration of 2-Fluoro-5-nitroaniline: Synthesis, Antibacterial, and Computational Study

Abstract: New derivatives of organotellurium and organomercury compounds have been synthesized in the reaction of 2-fluoro-5-nitroaniline with mercuric acetate and further with tellurium(IV) tetrabromide Reaction of (4-amino-5-fluoro-2-nitrophenyl)tellurium(IV) tribromide with 4-hydroxyphenyl mercury(II) chloride gives asymmetrical diaryltellurium(IV) dibromide, whereas reaction of (4-amino-5-fluoro-2-nitrophenyl)mercury(II) chloride with phenol and 4-hydroxy benzaldehyde produces a new aryl mercury(II) chloride that contains the azomethine and azo groups Reaction of aryl mercury(II) chloride with tellurium(IV) tetrabromide results in aryaltellurium(IV) tribromide furnished by the azomethine and azo groups Reduction of unsymmetrical diaryltellurium(IV) dibromide and aryltellurium(IV) tribromide by hydrazine hydrate leads to the corresponding asymmetrical diaryltelluride and diarylditelluride Structures of the new synthesized compounds are supported by FT-IR and 1H NMR spectra Anti-bacterial activity of the new products has been tested against Klebsiella pneumonia Proteus, Escherichia coli, Pseudomonas spp, and Staphylococcus aureus The compounds are characterized as highly active The molecular structure level and energies of compounds have been computed through the Density Functional Theory (DFT)

Organomercury Captured by Lyase Overexpressed Escherichia coli and Its Evaluation by In-Cell Radiometry*

Abstract: Organomercury lyase (MerB) overexpressed in Escherichia coli captured and decomposed organomercury compounds, and it has been detected by radioactive analysis with neutron irradiation. Genetically modified E. coli captures a lot of mercury from a cultivation solution with about 80% recovery, when the bacteria are growing during 24 to 72 hours. Since the modified E. coli has no additive gene for mercury metabolism, the bacteria could hold mercury tightly by the MerB enzyme in their cell and do not release them into medium. In the later, 72 hours after, bacteria have less recovery ratio; it may be affected by undecompsed mercury compounds in bacteria growth. The recovery ability of the bacteria would not be changed by addition of the MerB producing reagent (IPTG). A quantitative value of mercury atom is estimated by an emission of γ-ray by reactor neutron from a dried cell or solution on a filter paper, which is available for nondestructive testing of bacteria holding mercury atoms. In this method an efficient recovery system of toxic mercury from a polluted solution has been archived without destruction of samples, so called in-cell analysis.