Topic
Penicillin
About: Penicillin is a research topic. Over the lifetime, 17916 publications have been published within this topic receiving 368480 citations. The topic is also known as: penicillin antibiotic & PCN.
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TL;DR: Oral therapy with adequate parental counseling is as efficacious as intramuscular injection in children with streptococcal pharyngitis.
Abstract: Of 300 children with streptococcal pharyngitis, one group received a mixture of penicillin G procaine and penicillin G benzathine; a second was given a prescription for ten days of penicillin phenoxymethyl (parents of this group were given no special instructions); and a third was given identical prescriptions but their parents received specific counseling on the importance of taking the medication. There were 14 treatment failures plus relapse in group 1, 25 in group 2, and 10 in group 3. Compliance in taking penicillin was 58% in group 2 and 80% in group 3, a significant difference. Oral therapy with adequate parental counseling is as efficacious as intramuscular injection.
116 citations
116 citations
TL;DR: The PROTEKT US study confirms the widespread prevalence of antimicrobial resistance among common bacterial respiratory pathogens in the US, and re-affirms the importance of continued surveillance to guide optimum empiric therapy for patients with Community-acquired respiratory tract infections (CARTIs).
116 citations
116 citations
TL;DR: Penicillium chrysogenum strains were constructed which express a mutant acyltransferase lacking the putative targeting signal for microbody proteins, demonstrating the involvement of microbodies in penicillin production.
116 citations