Showing papers on "Penicillium griseofulvum published in 1955"
TL;DR: In this paper, the authors considered the general problem of the biosynthesis of depsides and depsidones and demonstrated that the mould Penicillium griseofulvum Dierckx (Raistrick's strain P68) elaborates 2-hydroxy-6-methylbenzoic acid (VII) by the head-to-tail linkage of acetic acid units.
Abstract: The general problem of the biosynthesis of depsides and depsidones is considered. Feeding experiments using sodium acetate isotopically labelled in the carboxyl group have demonstrated that the mould Penicillium griseofulvum Dierckx (Raistrick's strain P68) elaborates 2-hydroxy-6-methylbenzoic acid (VII) by the head-to-tail linkage of acetic acid units in accord with the hypothesis of Birch and Donovan (1953). This demonstration constitutes the first definite support for the hypothesis based on bio- chemical experiments.
116 citations
TL;DR: Griseofulvin, previously known as a metabolic product of Penicillium griseoFULvum Dierckx, P. nigricans (Bain.) Thorn and P. urticae Bain.
Abstract: Griseofulvin, previously known as a metabolic product of Penicillium griseofulvum Dierckx, P. nigricans (Bain.) Thorn and P. urticae Bain., has now been found to be produced by some strains of P. raistrickii Smith. Strains of this species vary in their capacity to produce sclerotia and conidia in culture; those strains that produce abundant sclerotia produce few conidia, those that produce abundant conidia produce few sclerotia. Conidial strains produce good yields of griseofulvin but sclerotial strains produce little or none.
18 citations