Topic
Penicillium griseofulvum
About: Penicillium griseofulvum is a research topic. Over the lifetime, 169 publications have been published within this topic receiving 2702 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this paper, 10 new (1-10) and 26 known (11-36) compounds were isolated from Penicillium griseofulvum MCCC 3A00225, a deep sea derived fungus.
Abstract: Ten new (1-10) and 26 known (11-36) compounds were isolated from Penicillium griseofulvum MCCC 3A00225, a deep sea-derived fungus. The structures of the new compounds were determined by detailed analysis of the NMR and HRESIMS spectroscopic data. The absolute configurations were established by X-ray crystallography, Marfey's method, and the ICD method. All isolates were tested for in vitro anti-food allergic bioactivities in immunoglobulin (Ig) E-mediated rat basophilic leukemia (RBL)-2H3 cells. Compound 13 significantly decreased the degranulation release with an IC50 value of 60.3 μM, compared to that of 91.6 μM of the positive control, loratadine.
8 citations
TL;DR: Penifulvin A (1) as mentioned in this paper is a fungal metabolite with a previously undescribed ring system, isolated from cultures of an isolate of Penicillium griseofulvum (NRRL 35584) obtained from a white mycelial growth on a dead hardwood branch collected in a Hawaiian forest.
Abstract: Penifulvin A (1), a new fungal metabolite with a previously undescribed ring system, has been isolated from cultures of an isolate of Penicillium griseofulvum (NRRL 35584) obtained from a white mycelial growth on a dead hardwood branch collected in a Hawaiian forest. The structure was assigned by analysis of NMR data and confirmed by single-crystal X-ray diffraction analysis. Penifulvin A (1) shows significant activity in dietary assays against the fall armyworm Spodoptera frugiperda.
7 citations
Journal Article•
TL;DR: It is feasible that the species-specific primers could be used as probes for the detection of environmental pollution dominant species, Penicillium griseofulvum, since the frequency of occurrence and amount of this strain could preferably indicate the pollution degree.
Abstract: OBJECTIVE PCR method was used to detect Penicillium griseofulvum, a dominant species in marine contaminated sediments and thereby to deduce the contamination degree. METHODS According to differences in internal transcribed space (ITS) sequences of Penicillium genus and specific IAO sequence, we designed species-specific primers AS1/RS4 and IAO1/IAO2 of Penicillium griseofulvum and established the corresponding PCR systems. By using PCR and nested-PCR, the detection sensitivity was compared. RESULTS The primers could exclusively amplify destined DNA fragment from environment. Using AS1/RS4 as primers, the detection sensitivity could be 10 fg/microL and 10 spores. The detection sensitivity for the sediments was 10(2) spores/0.25 g sediments. While the detection was unsensitive when using IAO1/IAO2 as primers. CONCLUSION It is feasible that the species-specific primers be used as probes for the detection of environmental pollution dominant species, Penicillium griseofulvum, because the frequency of occurrence and amount of this strain could preferably indicate the pollution degree.
7 citations
TL;DR: This is the first report of P. griseofulvum on apples during storage in Italy, and preliminary morphological identification of the fungus was confirmed by PCR using genomic DNA extracted from mycelia of pure cultures.
Abstract: In northern Italy, blue mold can occur generally on apples after 3 months of storage under controlled atmospheres. The mold can be caused by Penicillium griseofulvum Dierckx (synonym P. urticae Bainier). During 2008, several postharvest fruit rots were observed on apples (cv. Golden Delicious) after 180 to 240 days of storage at 1°C. Approximately 8% of the fruits showed blue mold. Apples had been cultivated in Aosta (Aosta Valley Region) and Lagnasco (Piedmont Region). Infected fruits showed soft, watery, brown spots enlarging rapidly at 20°C. There was a distinct margin between soft rotted flesh and firm healthy tissues. Under high humidity, masses of blue-green spores formed on the surface of the lesion. Apple fruit excisions from the margin between the healthy and diseased tissues were plated on potato dextrose agar (PDA), pH 5.6. The recovered fungus produced abundant mycelium and conidia, with the colonies attaining a diameter of 2.0 to 2.4 cm after 7 days at 20 ± 2°C on PDA. Colonies were mostly ye...
7 citations
TL;DR: The properties of an amino acid accumulating system were investigated in Penicillium griseofulvum Dierckx by following the uptake of l -leucine by mycelium in the absence of external glucose, and 98% of the leucine accumulated was shown to be in unbound form in the cell.
Abstract: The properties of an amino acid accumulating system were investigated in Penicillium griseofulvum Dierckx by following the uptake of l -leucine (and other amino acids) by mycelium in the absence of external glucose. In these conditions 98% of the leucine accumulated was shown to be in unbound form in the cell. The kinetics of uptake at 25 °C may be described by a Michaelis—Menten relation with an apparent Km of 2·22 × 10−3 m . Uptake of leucine by the mycelium was abolished by several metabolic inhibitors, and the amount accumulated was markedly dependent on the pH of the medium, on the age of the mycelium, and on the source of nitrogen on which the mycelium had previously been growing. Studies of simultaneous uptake of several amino acids suggested the presence of more than one mechanism of uptake with broad but differing specificities.
7 citations