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Perfusion scanning

About: Perfusion scanning is a research topic. Over the lifetime, 9496 publications have been published within this topic receiving 223860 citations. The topic is also known as: perfusion imaging.


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Journal ArticleDOI
TL;DR: A practical stepwise approach for interpretation of myocardial CTP that should add to the clinical applicability of this modality and uses already published methods from multiple clinical studies.

71 citations

Journal ArticleDOI
TL;DR: Worsening fluency was associated with perfusion decrements in left dorsolateral prefrontal cortex, anterior cingulate cortex and ventral caudate nucleus and worsened fluency in category fluency after STN-DBS patients.

71 citations

Journal ArticleDOI
TL;DR: The current status of MRI for acute stroke imaging with a special focus is the ischemic stroke and the basic principle and diagnostic value of different MRI sequences are illustrated.
Abstract: Cerebral stroke is one of the most frequent causes of permanent disability or death in the western world and a major burden in healthcare system The major portion is caused by acute ischemia due to cerebral artery occlusion by a clot The minority of strokes is related to intracerebral hemorrhage or other sources To limit the permanent disability in ischemic stroke patients resulting from irreversible infarction of ischemic brain tissue, major efforts were made in the last decade To extend the time window for thrombolysis, which is the only approved therapy, several imaging parameters in computed tomography and magnetic resonance imaging (MRI) have been investigated However, the current guidelines neglect the fact that the portion of potentially salvageable ischemic tissue (penumbra) is not dependent on the time window but the individual collateral blood flow Within the last years, the differentiation of infarct core and penumbra with MRI using diffusion-weighted images (DWI) and perfusion imaging (PI) with parameter maps was established Current trials transform these technical advances to a redefined patient selection based on physiological parameters determined by MRI This review article presents the current status of MRI for acute stroke imaging A special focus is the ischemic stroke In dependence on the pathophysiology of cerebral ischemia, the basic principle and diagnostic value of different MRI sequences are illustrated MRI techniques for imaging of the main differential diagnoses of ischemic stroke are mentioned Moreover, perspectives of MRI for imaging-based acute stroke treatment as well as monitoring of restorative stroke therapy from recent trials are discussed

71 citations

Journal ArticleDOI
TL;DR: This pilot study confirms that UF-SPECT provides high-quality fast myocardial perfusion imaging and suggests that it may allow a more-accurate evaluation of both extent and severity of myocardIAL ischemia in patients with coronary artery disease.
Abstract: Background— A novel technology has been developed for ultrafast (UF) single-photon emission CT (SPECT) myocardial perfusion imaging by using a pinhole collimation design and multiple cadmium zinc telluride crystal arrays. The purpose of this study was to compare myocardial perfusion imaging obtained by UF-SPECT with standard (S) SPECT in patients with known or suspected coronary artery disease. Methods and Results— A total of 34 patients underwent single-day 99mTc-tetrofosmin stress/rest myocardial perfusion imaging. UF-SPECT was performed 10 minutes before S-SPECT. Images were qualitatively analyzed, and the summed stress score and summed rest score were calculated. The segmental tracer uptake value (percentage of maximum myocardial uptake) also was quantified for both UF- and S-SPECT. When only 29 of 34 patients with significant coronary lesions were analyzed, the summed stress score was 10.1±4.4 versus 6.4±2.9, respectively, for UF- and S-SPECT ( P =0.002). Qualitative and quantitative per-patient analysis showed similar results in detection of coronary artery disease for UF- and S-SPECT. In contrast, per-vessel analysis demonstrated higher regional sensitivity of UF- versus S-SPECT. UF-SPECT showed higher sensitivity in detecting multivessel disease ( P =0.003) versus S-SPECT. Conclusions— This pilot study confirms that UF-SPECT provides high-quality fast myocardial perfusion imaging and suggests that it may allow a more-accurate evaluation of both extent and severity of myocardial ischemia in patients with coronary artery disease.

71 citations

Journal ArticleDOI
01 Jan 2013-Stroke
TL;DR: CTP-CBV demonstrates the highest interobserver agreement for individual ASPECTS regions, and highest concordance was shown for caudate, lentiform, and M1–M3, whereas performance for internal capsule and M4–M6 was poorer.
Abstract: Background and Purpose—The Alberta Stroke program early CT score (ASPECTS) is a semiquantative scale for estimating extent and distribution of early ischemic changes within the MCA territory in the acute stroke setting. Good interobserver agreement of total ASPECTS is demonstrated for noncontrast CT (NCCT) and other imaging modalities. Our purpose is to assess interobserver agreement for individual ASPECTS regions for different imaging modalities. Methods—One hundred and eighty-one consecutive patients presenting with acute stroke symptoms within 4.5 hours of onset were included. Four readers assigned total and individual ASPECTS for NCCT, CT angiography source images (CTA-SI), and CTP maps of cerebral blood volume (CTP-CBV). Interobserver agreement was assessed by measuring internal consistency and concordance of total and individual ASPECTS using Cronbach’s α and intraclass correlation coefficient, respectively. Results—Total ASPECTS demonstrated very good concordance and internal consistency for all 3 ...

71 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023181
2022372
2021394
2020362
2019407
2018336