Topic
Perfusion scanning
About: Perfusion scanning is a research topic. Over the lifetime, 9496 publications have been published within this topic receiving 223860 citations. The topic is also known as: perfusion imaging.
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TL;DR: A systematic evaluation of the empirical data concerning deficits in mental ability, brain perfusion, and cerebral functioning due to chronically low blood pressure suggests that more attention should be allocated to chronic hypotension in both research and clinical practice.
Abstract: This review article includes a systematic evaluation of the empirical data concerning deficits in mental ability, brain perfusion, and cerebral functioning due to chronically low blood pressure. A number of studies have provided strong evidence for reduced cognitive performance in hypotension, particularly in the domains of attention and memory. EEG studies have demonstrated that the hypotension-related poorer mental ability is also reflected in diminished cortical activity. Contrary to convention, more recent research has suggested a deficient regulation of cerebral blood flow in persons with low blood pressure. In addition to reduced tonic brain perfusion, studies demonstrated insufficient adjustment of blood flow to cognitive requirements. Altogether, these findings suggest that more attention should be allocated to chronic hypotension in both research and clinical practice.
135 citations
Journal Article•
TL;DR: When patients move during 201Tl tomographic myocardial perfusion imaging, the incidence and character of false-positive results depend on the angle of camera rotation at which the movement occurs, the direction of the movement and distance of themovement.
Abstract: We evaluated the effect of patient motion on inducing false-positive tomographic 201Tl myocardial perfusion studies. The effects of the angle of camera rotation at which movement occurs, the direction of movement and the distance of movement were studied. Movement was stimulated by shifting the raw data from normal motion-free 201Tl tomographic myocardial perfusion studies. The visual detectability of motion artifact was evaluated with receiver-operating characteristic curve analysis. The clinical importance of patient movement was determined by measuring the incidence of quantitative bull's-eye abnormalities induced by motion. Visual artifacts were more detectable and quantitative abnormalities more frequent as the distance of movement increased. Artifacts from 3.25 mm of movement were not visually detectable. Artifacts from 6.5 mm of movement were visually detectable, but were infrequently clinically important. Movement of 13 mm or greater frequently caused quantitative abnormalities. Quantitative abnormalities from axial movement were more frequent than artifacts from lateral movement. Quantitative abnormalities were more frequent when the movement occurred at the beginning or end. We conclude that when patients move during 201Tl tomographic myocardial perfusion imaging, the incidence and character of false-positive results depend on the angle of camera rotation at which the movement occurs, the direction of the movement and distance of the movement.
135 citations
TL;DR: Arterial spin labeling (ASL) imaging soon will be available as a routine clinical perfusion imaging sequence for a significant number of MR imaging scanners, and familiarity with the available sequence parameter options and the common appearances of pathology facilitates perfusion interpretation.
135 citations
TL;DR: Although the changes seen in the inferior frontal cortex and occipital cortex may be related to anxiety experienced by the patients during the study, the pattern of hippocampal hypoperfusion appears to be characteristic of panic disorder.
135 citations
TL;DR: Electrical impedance tomography can be regarded as a promising technique to estimate the left-right division of pulmonary perfusion and ventilation in patients with lung cancer.
Abstract: Electrical impedance tomography (EIT) is a technique that makes it possible to measure ventilation and pulmonary perfusion in a volume that approximates to a 2D plane. The possibility of using EIT for measuring the left-right division of ventilation and perfusion was compared with that of radionuclide imaging. Following routine ventilation (81mKr) and perfusion scanning (99mTc-MAA), EIT measurements were performed at the third and the sixth intercostal level in 14 patients with lung cancer. A correlation (r = 0.98, p < 0.005) between the left-right division for the ventilation measured with EIT and that with 81mKr was found. For the left-right division of pulmonary perfusion a correlation of 0.95 (p < 0.005) was found between the two methods. The reliability coefficient (RC) was calculated for estimating the left-right division with EIT. The RC for the ventilation measurements was 94% and 96% for the perfusion measurements. The correlation analysis for reproducibility of the EIT measurements was 0.95 (p < 0.001) for the ventilation and 0.93 (p < 0.001) for the perfusion measurements. In conclusion, EIT can be regarded as a promising technique to estimate the left-right division of pulmonary perfusion and ventilation.
134 citations