Topic
Phosphofructokinase
About: Phosphofructokinase is a research topic. Over the lifetime, 3241 publications have been published within this topic receiving 106624 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this article, the role of HIF-1 as a mediator of adaptive responses to hypoxia that underlie cellular and systemic oxygen homeostasis was investigated in Hep3B cells.
1,817 citations
TL;DR: AMPK phosphorylates and activates heart PFK-2 in vitro and in intact cells, and is likely to be involved in the stimulation of heart glycolysis during ischaemia.
804 citations
TL;DR: Findings suggest that overexpression of the c-Myc oncoprotein deregulates glycolysis through the activation of several components of the glucose metabolic pathway.
768 citations
TL;DR: It is concluded that shifts in intracellular pH are important in the regulation of phosphofructokinase, but that this effect makes interpretation of data from intact muscle quite difficult.
653 citations
TL;DR: Acute loading of the liver with fructose causes sequestration of inorganic phosphate in fructose-1-phosphate and diminished ATP synthesis, and the inhibition by ATP of the enzymes of adenine nucleotide degradation is removed and uric acid formation accelerates with consequent hyperuricemia.
634 citations