Topic
Pneumothorax
About: Pneumothorax is a research topic. Over the lifetime, 12241 publications have been published within this topic receiving 190723 citations. The topic is also known as: Pneumothorax.
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TL;DR: Lung ultrasound can help the clinician make a rapid diagnosis in patients with acute respiratory failure, thus meeting the priority objective of saving time.
1,510 citations
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TL;DR: Small airways obstruction, mediated by an influx of inflammatory cells, often characterises pneumothorax and may become manifest in the smaller airways at an earlier stage with ‘emphysema-like changes’ (ELCs).
Abstract: The term ‘pneumothorax’ was first coined by Itard and then Laennec in 1803 and 1819 respectively,1 and refers to air in the pleural cavity (ie, interspersed between the lung and the chest wall). At that time, most cases of pneumothorax were secondary to tuberculosis, although some were recognised as occurring in otherwise healthy patients (‘pneumothorax simple’). This classification has endured subsequently, with the first modern description of pneumothorax occurring in healthy people (primary spontaneous pneumothorax, PSP) being that of Kjaergaard2 in 1932. It is a significant global health problem, with a reported incidence of 18–28/100 000 cases per annum for men and 1.2–6/100 000 for women.3
Secondary pneumothorax (SSP) is associated with underlying lung disease, in distinction to PSP, although tuberculosis is no longer the commonest underlying lung disease in the developed world. The consequences of a pneumothorax in patients with pre-existing lung disease are significantly greater, and the management is potentially more difficult. Combined hospital admission rates for PSP and SSP in the UK have been reported as 16.7/100 000 for men and 5.8/100 000 for women, with corresponding mortality rates of 1.26/million and 0.62/million per annum between 1991 and 1995.4
With regard to the aetiology of pneumothorax, anatomical abnormalities have been demonstrated, even in the absence of overt underlying lung disease. Subpleural blebs and bullae are found at the lung apices at thoracoscopy and on CT scanning in up to 90% of cases of PSP,5 6 and are thought to play a role. More recent autofluorescence studies7 have revealed pleural porosities in adjacent areas that were invisible with white light. Small airways obstruction, mediated by an influx of inflammatory cells, often characterises pneumothorax and may become manifest in the smaller airways at an earlier stage with ‘emphysema-like changes’ (ELCs).8
Smoking has been implicated in this …
1,066 citations
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TL;DR: The sensitivity of bronchoscopy is high for endobronchial disease and poor for peripheral lesions, while TTNA is associated with a higher rate of pneumothorax compared with bronchoscopic procedures and R-EBUS and EMN are emerging technologies for the diagnosis of peripheral lung cancer.
838 citations
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TL;DR: Ultrasound was a sensitive test for detection of pneumothorax, although false-positive cases were noted, and the principal value of this test was that it could immediately exclude anterior pneumothsorax.
695 citations
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TL;DR: The presence of a "lung point" allows positive diagnosis of pneumothorax at the bedside using ultrasound, and has an overall sensitivity of 66% (75% in the case of radio-occult pneumothsorax alone) and a specificity of 100%.
Abstract: Objective: We studied an ultrasound sign, the fleeting appearance of a lung pattern (lung sliding or pathologic comet-tail artifacts) replacing a pneumothorax pattern (absent lung sliding plus exclusive horizontal lines) in a particular location of the chest wall This sign was called the "lung point" Design: Prospective study Setting: The medical ICU of a university-affiliated teaching hospital Patients: The "lung point" was sought in 66 consecutive cases of proven pneumothorax analyzable using ultrasound – including 8 radio-occult cases diagnosed by means of CT – and in 233 consecutive hemithoraces studied by CT and free of pneumothorax – including 17 cases where pneumothorax was suspected Results: The "lung point" was observed in 44 of 66 cases of pneumothorax (including 6 of 8 radio-occult cases) and in no case in the control group The location of this sign roughly correlated with the radiological size of the pneumothorax The "lung point" therefore had an overall sensitivity of 66% (75% in the case of radio-occult pneumothorax alone) and a specificity of 100% Conclusion: The presence of a "lung point" allows positive diagnosis of pneumothorax at the bedside using ultrasound
585 citations