Showing papers on "Polyamine binding published in 2013"

TL;DR: Various NMDA receptor antagonists, including glycine binding site inhibitor kynurenic acid, polyamine binding site inhibitors ketamine, and channel blocking agent magnesium sulfate, attenuated ischemia-reperfusion-induced AKI and significantly reduced oxidative stress, which suggests a role for NMDA receptors and the importance of regulating its allosteric sites in AKI.

TL;DR: This work develops a detailed mapping approach to localize binding sites of physiologically essential channel blockers by scanning the effects of cysteine modification at multiple pore-lining positions on the blocking properties of a library of polyamine analogs, demonstrating that the effects are position- and blocker-dependent.

TL;DR: Results suggest that systemic administration of polyamine binding site ligands modulate memory reconsolidation in Wistar rats.