Showing papers on "Polygonum published in 2019"
TL;DR: In this article, the halophyte sea knotgrass (Polygonum maritimum L.) was used as source of phenolics and flavonoids-enriched extracts with skincare properties, for the cosmetic industry.
17 citations
TL;DR: Five endophytes were found to have the greatest potential as inoculants to assist P. hydropiper in future P-phytoextraction studies.
14 citations
TL;DR: Assessment of the zonation of two emergent macrophytes and experimentally tested the effects of water level fluctuations and competition on the growth of these two species show that P. acuminatum can dominate in shallower areas by having morphological adaptations to intermittent fluctuations in water level and a competitive advantage over P. ferrugineum.
11 citations
TL;DR: The quantitative analysis of multicomponents by the single-marker (QAMS) method was established and the relationship between F value and the steaming time was found to identify and differentiate Polygoni multiflori Radix Preaparata and its processed product.
Abstract: The quantitative analysis of multicomponents by the single-marker (QAMS) method was established and the relationship between F value (the ratio of the sum of the contents of emodin-8-O-β-D-glucopyranoside and physcion-8-O-β-D-glucopyranoside to the sum of the contents of emodin and physcion) and the steaming time was found to identify and differentiate Polygonum multiflorum Radix and its processed product. Emodin was considered as the control substance, and the correction factors of physcion, emodin-8-O-β-D-glucopyranoside, and physcion-8-O-β-D-glucopyranoside were computed. In addition, the contents of the four components were determined. When the F value is greater than or equal to 1.0, the sample was identified as Polygonum multiflorum Radix, and if the F value was between 0.6 and 1.0, the sample of Polygoni multiflori Radix Preaparata was processed incompletely. The F value of the qualified Radix Polygonum multiflorum should be no more than 0.6. However, the influence of different sample injection volumes and the chromatographic columns and instruments used on the durability of the correction factors and RSD ≤3% hindered accurate identification; therefore, a QAMS method using an external standard value with methodological verification was developed. We redefined the “Polygonum multiflorum rules.” The method using “Polygonum multiflorum rules” revised after optimization of the determination results was used, as it was accurate and led to convenient operation and low inspection costs, and moreover, the method could differentiate Polygoni multiflori Radix Preaparata and Polygonum multiflorum Radix medicinal samples and precisely identify samples that were different from the completely processed product Polygoni multiflori Radix Preaparata.
9 citations
TL;DR: Polygonum minus ethanolic extract at 100 and 200 mg/kg attenuates cisplatin-induced oxidative stress in the cerebral cortex via its antioxidant activity, and significantly reduced malondialdehyde level and significantly increased catalase activity compared to the cisPlatin group.
Abstract: Objective: To explore the protective effect of Polygonum minus ethanolic extract on cisplatin-induced neurotoxicity. Methods: In vitro test, total phenolic content assay and DPPH assay were performed to determine the antioxidant activity of Polygonum minus. For in vivo test, 30 male Sprague- Dawley rats were randomly divided into 5 groups: the control group, cisplatin 10 mg/kg, Polygonum minus 100 mg/kg, Polygonum minus 200 mg/kg and Polygonum minus 400 mg/kg. The control group and the cisplatin group were given distilled water whereas Polygonum minus groups received the respective dose of Polygonum minus extract orally for 14 d. On day 15, a single intraperitoneal administration of normal saline was given to the control group; while 10 mg/kg of cisplatin was given to the cisplatin group and Polygonum minus groups. Body weight, signs of illness, daily activity and mortality were observed at least once daily throughout the experimental period. On day 18, the anterior part of the brain was collected and processed for histological and ultrastructural analyses (right hemisphere). The remaining part (left hemisphere) of the brain was assayed to determine malondialdehyde and catalase levels for oxidative stress analyses. Results: Polygonum minus ethanolic extract possessed high phenolic content (977.6 mg GAE/g) and 95.9% DPPH radical scavenging activities. No mortality was observed in all groups. Rats in the cisplatin group were weak and less active compared to Polygonum minus treated rats. In the cisplatin group, disorganised cellular layers of the cerebral cortex were observed whereas rats treated with low and mid doses of Polygonum minus extract had normal cerebral cortex as in the control group. Mild ultrastructural changes were observed in rats treated with low and mid doses of Polygonum minus extract. Meanwhile, low and mid doses of Polygonum minus extract significantly reduced malondialdehyde level whereas low and mid doses of Polygonum minus extracts groups significantly increased catalase activity compared to the cisplatin group. Conclusions: Polygonum minus ethanolic extract at 100 and 200 mg/kg attenuates cisplatin-induced oxidative stress in the cerebral cortex via its antioxidant activity.
7 citations
TL;DR: Adventitious root cultures of P. multiflorum line AR-06 showed great potential for producing phenolic compounds and may provide an alternative to naturally grown plants as a potential biomass source for the production of bioactive compounds.
Abstract: The correlation between growth and accumulation of bioactive compounds was investigated in six genotypes of Polygonum multiflorum, grown in vitro, soil-grown (ex vitro), and as adventitious root cultures. Adventitious roots were induced on leaf and root explants from plantlets of the six genotypes grown in vitro. Line PM-06 achieved the highest biomass in vitro (0.91 g plant−1 FW; 0.1 g plant−1 (DW)), whereas line PM-05 produced the highest biomass ex vitro (54.67 g plant−1 FW; 12.93 g plant−1 DW). A comparison of the six lines found that total phenolic content (TPC) and total flavonoid content (TFC) were highest in roots from line PM-01 grown in vitro, but line PM-06 produced the highest levels of bioactive compounds in tubers (99.06 mg g−1 DW TPC; 42.31 mg g−1 DW TFC), which were 2.5-fold, 5.0-fold, and 4.8-fold higher than the highest levels produced by in vitro roots, in vitro shoots, and ex vitro shoots, respectively. Although adventitious root line AR-06 produced the greatest overall biomass (60.12 g L−1 FW; 6.36 g L−1 DW), bioactive content was highest in line AR-01 (50.35 mg g−1 DW TPC; 22.51 mg g−1 TFC). There was a strong correlation between phenolic production in plant roots grown in vitro and adventitious root lines, and plant roots grown ex vitro and adventitious root lines. Adventitious root cultures of P. multiflorum line AR-06 showed great potential for producing phenolic compounds. Such cultures may therefore provide an alternative to naturally grown plants as a potential biomass source for the production of bioactive compounds.
6 citations
TL;DR: Five new trans‐2,3,5,4′‐tetrahydroxystilbene 2‐O‐β‐d‐glucopyranoside (TSG)‐based stilbenes glycoside oligomers (1–5) were isolated from the roots of Polygonum multiflorum and exhibited moderate inhibitory activities against NO production in LPS‐stimulated RAW264.7 cells.
Abstract: Five new trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-d-glucopyranoside (TSG)-based stilbene glycoside oligomers (1-5) were isolated from the roots of Polygonum multiflorum. Their structures were elucidated by comprehensive spectroscopic analyses and chemical evidences. The absolute configurations of 1, 2, 4, and 5 were established by quantum-chemical electronic circular dichroism (ECD) calculations. Putative biosynthetic pathways of 1-5 were proposed using TSG as the key precursor. In addition, compounds 1 (multiflorumiside H) and 3 (multiflorumiside J) exhibited moderate inhibitory activities against NO production in LPS-stimulated RAW264.7 cells.
4 citations
4 citations
3 citations
01 Jan 2019
TL;DR: Morphological characters and fruit anatomy were analysed for distinguishing the new genus Caelestium, containing C. lazkovii and C. tianschanicum, from the genus Bactria in its updated circumscription, now containing only B. ovczinnikovii.
Abstract: Morphological characters and fruit anatomy were analysed for distinguishing the new genus Caelestium, containing C. lazkovii (= Bactria lazkovii), endemic of the Central Tien Shan (Kyrgyzstan), and C. tianschanicum (= Polygonum tianschanicum), endemic of the Eastern Tien Shan (Xinjiang, China), from the genus Bactria in its updated circumscription, now containing only B. ovczinnikovii, endemic of the Pamir (Tajikistan). The genus Caelestium was established based on the results of molecular analyses and the details of the secondary structure of pre-rRNA of the ITS1 and ITS2 loci, but its morphology is poorly known. The morphological characteristics of Bactria and Caelestium were compared, and the anatomy of fruit was examined for these taxa and some species of Persepolium and Atraphaxis. Caelestium lazkovii and C. tianschanicum share the morphology of their leaf blades, perianth, fruits and styles, but differ in the color of annual shoots, the size of the perianth and fruits. They resemble Bactria ovczinnikovii in their life form, morphology of shoots, ochreas, inflorescences, and sporoderm ornamentation, but differ from the latter in the shape of leaf blades, fruits, and styles, micromorphology of tepals, and exocarp structure. SEM and LM images illustrating morphological characters are provided. The geographic ranges of the taxa are presented on the distribution map. Morphological characteristics distinguishing Caelestium and Bactria from Atraphaxis, Persepolium, and Polygonum are discussed.
3 citations
TL;DR: It is suggested that the PM-70% MFL layer in the fraction of Sasao contains the components that inhibit the differentiation and activity of B cells.
Abstract: This study examined the effects of GATA-3-dependent Th2 cells and IgE inhibition by using PM-E and PM-70M isolated from Sasao. It was analyzed that the 70 % methanol layer contained adsorbed chromatograms of the fraction of sodium hypochlorite that inhibited GATA-3 transcription factor activity. As a result, PM-70 %MFL fraction seems to have an antiallergic effect by inhibiting GATA-3 which regulates Th2 cytokine. PM-30A, PM-70A, and PM-30A layers by inhibiting IgE secretion in B cells by co-culturing the fractions with anti-CD40/rmIL-6 and TNF-α mRNA and IgE were not different from control. However, expression of IL-6 and TNF-α mRNA was 0.69 ± 0.058 (p <0.001) and 0.72 ± 0.58 (p <0.05), respectively. The amount of IgE secretion was 94.6 ± 16.0, which was significantly decreased by 45.6% (p <0.01) compared with the control group. This study suggests that the PM-70% MFL layer in the fraction of Sasao contains the components that inhibit the differentiation and activity of B cells.
TL;DR: For the flowering aerial parts of Polygonum hydropiper L. species, harvested from Romanian flora, four polyphenolic acids were separated and quantified using HPTLC-UV densitometry, with ESI-MS confirmation as mentioned in this paper.
Abstract: For the flowering aerial parts of Polygonum hydropiper L. species, harvested from Romanian flora, four polyphenolic acids were separated and quantified using HPTLC-UV densitometry, with ESI-MS confirmation. Chlorogenic acid was found in the highest amount, followed by ferulic acid, p-coumaric acid and caffeic acid. The content of total polyphenols and caffeic acid derivatives was determined using spectrophotometric methods. In vitro antioxidant activity was evaluated using DPPH assay. Our studies bring new data regarding the phytochemical profile of P. hydropiper, as a natural source of polyphenols with antioxidant properties.
Patent•
15 Mar 2019
TL;DR: In this article, a polygonum multiflorum-aloe bowel-relaxing capsules are prepared from the following traditional Chinese medicine components in parts by weight: 75 parts of donkey-hide gelatin, 160 parts of aloes, 120 partsof polygonal multiflorm, 140 parts of cassia seeds, 75 part of lycium barbarum, 50 parts of atractylodes macrocephala, 120 parts of immature bitter oranges and 50 part of ginseng.
Abstract: The invention belongs to the field of traditional Chinese medicines and particularly discloses the improvement on a process for preparing polygonum multiflorum-aloe bowel-relaxing capsules. The polygonum multiflorum-aloe bowel-relaxing capsules are prepared from the following traditional Chinese medicine components in parts by weight: 75 parts of donkey-hide gelatin, 160 parts of aloes, 120 partsof polygonum multiflorum, 140 parts of cassia seeds, 75 parts of lycium barbarum, 50 parts of atractylodes macrocephala, 120 parts of immature bitter oranges and 50 parts of ginseng. According to theprocess, different preparation processes are adopted for different traditional Chinese medicines, contents of effective components are ensured, meanwhile, conventional auxiliary materials and amount ratios are screened, a polygonum multiflorum-aloe bowel-relaxing preparation process is improved, and the preferred preparation process has various property indexes such as water contents, disintegration time limits and dissolution rates which all meet requirements of the Chinese Pharmacopoeia, and is applicable to industrial large-scale production.
TL;DR: Both Pteroxygonum and Polygonum might have the same origin and could be classified into the same tribe among Polygonaceae and may have some taxonomic relationships with Fallopia, Rumex and Reynoutria.
28 Jun 2019
TL;DR: It was determined that many of nutritional properties studied were richer than some cultivated vegetable species.
Abstract: This research was carried out to determine nutritional content and chemical composition of knotgrass species ( Polygonum ) consumed as vegetable in the Middle Black Sea Region. Survey and field studies started in spring of 2011 (April-May) and were carried out in Samsun, Amasya , Ordu and Tokat where these species were intense. In the survey studies, five species were identified in 35 knotgrass samples as Polygonum arenastrum (12 materials), Polygonum aviculare (9 materials), Polygonum salicifolium (9 materials), Polygonum setosum (2 materials) and Polygonum luzuloides (3 materials). In the research, the highest amount of dry matter in P. salicifolium (26.68 %), the highest ash content in P. setosum (10.21 %), the highest N and protein contents in P. luzuloides (3.31 % and 20.70 %) and the highest Vitamin C in P.aviculare (105.46 mg/100g -1 ) were determined. The highest K content in P. luzuloides , the highest Zn, Mn and Ca contents in P. setosum , the highest P and Na contents in P. arenastrum and the highest Cu, Mg and Fe content in P. salicifolium were determined. Amounts of mineral matter showed variation according to plant species, genetic factors and ecology of samples taken from. It was determined that many of nutritional properties studied were richer than some cultivated vegetable species.
Patent•
10 Mar 2019
TL;DR: In this article, a method of processing polygonum multiflorum, which contains preparing a root extract solution and placing the solution under UV light for 1 to 24 hours, is described.
Abstract: Disclosed is a method of processing Polygonum multiflorum, the method contains preparing a root extract solution and placing the solution under UV light for 1 to 24 hours. Also disclosed is a composition prepared from the method that can be for use in the prevention, treatment, and management of diabetes in human and animal subjects.
Journal Article•
Patent•
08 Mar 2019
TL;DR: In this paper, a method for improving tobacco field soil by using local polygonum hydropiper as green manure was proposed, which consists of two steps: directly sowing polygonal hydropipers seeds at a tobacco nest of a shifting rod after a field ridge shifting rod is arranged at the end of tobacco harvesting; or sowing Polygonal Hydropiper seeds in the furrows of the original tobacco field when the middle leaves of the tobacco are harvested or are finished harvesting.
Abstract: The invention provides a method for improving tobacco field soil by using local polygonum hydropiper as green manure. The method comprises the following steps: directly sowing polygonum hydropiper seeds at a tobacco nest of a shifting rod after a field ridge shifting rod is arranged at the end of tobacco harvesting; or sowing polygonum hydropiper seeds in the furrows of the original tobacco fieldwhen the middle leaves of the tobacco are harvested or are finished harvesting; or after tobacco leaves are harvested, tobacco stubble plants are removed and tobacco field deep ploughing is carried out, polygonum hydropiper seeds are sown according to set row spacing of local tobacco planting; or polygonum hydropiper seeds are sown in different places; when the polygonum hydropiper plants grow to20-50cm, the polygonum hydropiper plants are cut and laid in the furrows of the tobacco field or on a set tobacco leaf planting line, and after biochemical treatment, the polygonum hydropiper plants are turned into the tobacco field and are ridged to be used as green manure to improve the soil of the tobacco field. According to the method for improving tobacco field soil by using polygonum hydropiper as green manure, the polygonum hydropiper is used as a new green manure for the tobacco field, a soil conditioning crop variety is newly added to the tobacco field, the soil of the tobacco field is improved by combining the advantages of the polygonum hydropiper, the improvement effect is good, and the production cost is greatly saved.
01 Jan 2019
Patent•
22 Apr 2019
TL;DR: In this paper, a Polygonum multiflorum extract is extracted by a solvent selected from the group consisting of purified water, hexane, 1,3-butyleneglycol, alcohol having 1 to 4 carbon atoms, ethylacetate, diethylether, dichloromethane, acetone, and a mixture thereof.
Abstract: The present invention relates to a composition for inhibiting formation of a biofilm containing a Polygonum multiflorum extract as an active ingredient, and a composition for preventing and alleviating diseases related to formation of a biofilm. The Polygonum multiflorum extract is extracted by a solvent selected from the group consisting of purified water, hexane, 1,3-butyleneglycol, alcohol having 1 to 4 carbon atoms, ethylacetate, diethylether, dichloromethane, acetone, and a mixture thereof.
Patent•
09 Apr 2019
TL;DR: Wang et al. as discussed by the authors showed that polygonum sinense polysaccharide extractive can inhibit the release of proinflammatory factors and promote anti-inflammatory factors, reducing pulmonary capillary permeability, reducing pneumorrhagia and pulmonary edema.
Abstract: The invention belongs to the field of traditional Chinese medicine, and particularly relates to application of polygonum sinense polysaccharide to preparation of drugs for preventing and treating viral pneumonia. Total polysaccharide extractive is obtained in traditional Chinese medicine polygonum sinense through separation and extraction, the average yield is greater than 2 percent, and the polysaccharide content is greater than 60 percent. Experiment results show that polygonum sinense polysaccharide extractive can inhibit the release of proinflammatory factors, promote the release of anti-inflammatory factors, reduce pulmonary capillary permeability, reduce pneumorrhagia and pulmonary edema, and inhibit systemic or pulmonary local inflammation reaction, thereby reducing acute lung injury; and a whole experiment show that the polygonum sinense polysaccharide extractive has an obvious inhibiting effect on mice acute pneumonia induced by influenza virus a H1N1. The polygonum sinense polysaccharide can be further applied to preparation of drugs for preventing and treating viral pneumonia.
Patent•
21 May 2019
TL;DR: In this article, a method for extracting a high-activity alpha-glucosidase inhibitor from polygonum hydropiper is described. But the method is not suitable for the extraction of proteins.
Abstract: The invention relates to the technical field of natural medicinal chemistry, in particular to a method for extracting a high-activity alpha-glucosidase inhibitor from polygonum hydropiper. The extraction method comprises the following steps: taking dried powder, crushing the powder, executing extraction with ethanol for three times, concentrating an extracting solution, and removing a solvent to obtain a polygonum hydropiper ethanol extract; adding water to suspend the polygonum hydropiper, executing multiple times of execution with petroleum ether to obtain a polygonum hydropiper petroleum ether extract, and making the polygonum hydropiper petroleum ether extract pass through a silica gel chromatographic column two times to obtain the high-activity alpha-glucosidase inhibitor extracted from polygonum hydropiper. The high-activity alpha-glucosidase inhibitor obtained by adopting the extraction method has excellent alpha-glucosidase inhibitory activity which is 122 times of the activityof a positive control drug acarbose.
01 Jan 2019
Patent•
06 Dec 2019
TL;DR: In this article, a method for enriching polygonum hydropiper volatile oil by adopting macroporous resins was proposed, which has a very good treatment effect on acute soft tissue contusion of mice, and has an equivalent effect and no statistical difference compared with positive control Yunnan Baiyao spray.
Abstract: The invention discloses a method for enriching polygonum hydropiper volatile oil by adopting macroporous resin. The method comprises the following steps: firstly, carrying out ultrasonic extraction for 30-60 minutes by utilizing ethanol with the mass fraction of 75-85%, after filtering, diluting a filtrate until the ethanol concentration is 40%, carrying out water eluting with DPH100 type macroporous resin or strongly acidic cationic resin until effluent is colorless, and finally carrying out eluting with ethanol with the mass fraction of 90%, so as to collect effluent which is the volatile component of polygonum hydropiper. The polygonum hydropiper volatile oil prepared by the method has a very good treatment effect on acute soft tissue contusion of mice, has a very remarkable difference(P is less than 0.05) compared with a blank group, and has an equivalent effect and no statistical difference compared with positive control Yunnan Baiyao spray; and mouse anti-inflammatory experiments show that the polygonum hydropiper volatile oil prepared by the method has the effect of inhibiting xylene-induced inflammation of mice, so that the process method can be applied to a preparation process of traumatic injury medicines.
Patent•
29 Jan 2019
TL;DR: In this article, a chlorosulfonic acid-pyridine method is adopted to conduct sulfating modification on polysaccharide from polygonum ciliinerve (PCP), and an optimal reaction condition is screened out through an orthogonal test, and the optimal reaction conditions comprises that the ratio of chloros sulfonic acid to pyridine is 1:8, the reaction temperature is 95 DEG C and the reaction time is 1 h The obtained product is high in substitution degree and activity
Abstract: The invention discloses a preparation method of a sulfated Polygonum ciliinerve polysaccharide product with effect of preventing piglet diarrhea According to the invention, a chlorosulfonic acid-pyridine method is adopted to conduct sulfating modification on polysaccharide from Polygonum ciliinerve (PCP), an optimal reaction condition is screened out through an orthogonal test, and the optimal reaction condition comprises that the ratio of chlorosulfonic acid to pyridine is 1:8, the reaction temperature is 95 DEG C and the reaction time is 1 h The obtained product is high in substitution degree and activity A CCK 8 method is combined with RT-PCR detection to confirm that the sulfated polysaccharide from Polygonum ciliinerve (sPCP) can effectively inhibit replication and proliferation ofporcine transmissible gastroenteritis virus (TGEV), and inhibit Escherichia coli and Shigella, and can improve immune function with an effect significantly better than that of polysaccharide from Polygonum ciliinerve An optimal drug delivery mode and dosage are screened out The prepared sulfated Polygonum ciliinerve polysaccharide product can improve the antiviral and immunopotentiating activity of polysaccharide from Polygonum ciliinerve
Patent•
09 Jul 2019
TL;DR: In this article, a quality detection method for the prepared radix polygonum multiflorum thunb is characterized in that the fingerprint, the DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activity fingerprint and the active common peak of the of the radix polygons are subjected to spectrum effect correlation researching on the basis of a HPLC (High Performance Liquid Chromatography)-DPPH combined technology.
Abstract: The invention belongs to the technical field of traditional Chinese medicine quality standard detection, and discloses a quality detection method for prepared radix polygonum multiflorum thunb. The quality detection method for the prepared radix polygonum multiflorum thunb is characterized in that the fingerprint, the DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activity finger-print and the active common peak of the of prepared radix polygonum multiflorum thunb are subjected to spectrum effect correlation researching on the basis of a HPLC (High Performance Liquid Chromatography)-DPPH combined technology, the oxidation resistance effect of the prepared radix polygonum multiflorum thunb is used for judging the quality of the prepared radix polygonum multiflorum thunb, and a scientific and perfect oxidation resistance quality evaluation and control standard for the prepared radix polygonum multiflorum thunb is established. The quality detection method disclosed by the invention has the advantages of being quick in response, visual in results, accurate in determining the nature, simple in operation and good in reproducibility.
Patent•
10 Mar 2019TL;DR: In this article, a method of processing polygonum multiflorum, which contains preparing a root extract solution and placing the solution under UV light for 1 to 24 hours, is described.
Abstract: Disclosed is a method of processing Polygonum multiflorum, the method contains preparing a root extract solution and placing the solution under UV light for 1 to 24 hours. Also disclosed is a composition prepared from the method that can be for use in the prevention, treatment, and management of diabetes in human and animal subjects.
Patent•
28 Jun 2019
TL;DR: In this paper, a seedling growth method and a cultivation method for Polygonum hydropiper was proposed for the field of traditional Chinese herbs, in particular to a growing method of polygonum hyphropiper.
Abstract: The invention relates to the field of cultivation of traditional Chinese herbs, in particular to a cultivation method of Polygonum hydropiper, and provides a seedling growth method and cultivation method for Polygonum hydropiper. The cultivation method herein comprises 1) treating a field, to be specific, turning the field to a depth of 20-30 cm; 2) transplanting, to be specific, transplanting seedlings of Polygonum hydropiper on April to May, the seedlings being acquired via the seedling growth method; 3) applying fertilizers, to be specific, applying 10-15 kg of urea per mu one week after transplanting, and applying 25-35 kg of nitro-compound fertilizer per mu one month later; 4) irrigating, to be specific, keeping soil moist; 5) harvesting, to be specific harvesting on October to September. The cultivation method of the invention can provide higher yield and better quality of Polygonum hydropiper and is very worthy of application.