Topic
Polygonum
About: Polygonum is a research topic. Over the lifetime, 1230 publications have been published within this topic receiving 12765 citations.
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TL;DR: Two new components were isolated from the ether extract of Polygonum minus ; a flavone: 6,7-methylenedioxy-5,3′, 4′, 5′-tetramethoxyflavone and a methyl flavonol: 6.7-4′,5′-dimethylenediooxy-3,5, 3′-trimethoxyFLavone as discussed by the authors.
34 citations
TL;DR: In this article, the crude polysaccharide (PMTP) was isolated from polygonum multiflorum thunb through hot water extraction followed by ethanol precipitation, and the results exhibited PMTP has powerful scavenging abilities, especially on ABTS, DPPH and Hydroxyl radicals.
Abstract: The crude polysaccharide (PMTP) was isolated from Polygonum Multiflorum Thunb through hot water extraction followed by ethanol precipitation. Through antioxidant assay in vitro, the results exhibited PMTP has powerful scavenging abilities, especially on ABTS, DPPH and Hydroxyl radicals. Therefore, the crude polysaccharide from P. Multiflorum Thunb should be explored as a novel potential antioxidant.
34 citations
TL;DR: Results support the use of P. spectabile as antimicrobial agent as well on 4 viruses strains.
33 citations
TL;DR: High catalase (CAT) and guaiacol peroxidase (G-POD) activities, and low malondialdehyde (MDA) production, with increasing culture scale, are revealed, which may indicate low-level oxidative damage to the cultures.
Abstract: Polygonum multiflorum Thunb. is an important medicinal plant that synthesizes an array of phenolic compounds. Its roots are used in a variety of pharmacological and cosmetic formulations, notably as hair dye. In the present study, the inoculum density (3–15 g/L) and culture period (1–7 weeks) were optimized in a 3 L bioreactor. High root biomass (14.18 g/L dry weight (DW)) was recorded with an inoculum of 7 g/L (p ≤ 0.05), which is consistent with the results for 5 and 10 g/L. However, significantly higher yield of bioactive compounds (53.87 mg/g DW total phenolics and 27.96 mg/g DW total flavonoids) with high free radical scavenging activity was obtained in root samples from 5 g/L inoculum density. A 4 week culture period was sufficient for optimum root growth and metabolite production. The optimized conditions were used for large-scale (5 and 20 L) and pilot-scale (500 L) studies. Considering that the continuous aeration of root cultures may lead to oxidative stress, antioxidant enzyme activity and lipid peroxidation also were studied. The results revealed high catalase (CAT) and guaiacol peroxidase (G-POD) activities, and low malondialdehyde (MDA) production, with increasing culture scale (20 and 500 L), which may indicate low-level oxidative damage to the cultures. An optimal yield of 4.01 kg dry root biomass with 287.12 mg/L of total phenolic productivity was achieved in a 500 L pilot-scale bioreactor. This work can pave the way for commercial production of biomass and secondary metabolites at the industrial level, and meet the rising demand for natural ingredients, especially in the pharmaceutical and cosmetic industries.
33 citations
TL;DR: One new stillbene glucoside (6), along with five known compounds (1–5), were isolated from the roots of Polygonum multiflorum Thumb, and their chemical structures established based on physicochemical and spectroscopic data.
Abstract: One new stillbene glucoside (6), along with five known compounds (1–5), were isolated from the roots ofPolygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound3 showed DNA topoisomerase I and II inhibitory activities.
33 citations