Topic
Polysomnography
About: Polysomnography is a research topic. Over the lifetime, 19527 publications have been published within this topic receiving 858718 citations. The topic is also known as: PSG & polysomnogram.
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TL;DR: Independent of measures of body habitus, lack of exercise was associated with increased severity of sleep-disordered breathing and the odds of having moderate or worse sleep- Disordered breathing significantly decreased with increasing level of exercise.
Abstract: Study Objectives: The degree to which physical exercise habits are related to sleep-disordered breathing is not known. We sought to investigate the association between a single-item exercise question and laboratory-assessed sleep-disordered breathing. Design: A population-based cross-sectional epidemiologic study of adults measured the association between exercise and sleep-disordered breathing. Hours of weekly planned exercise were assessed by questionnaire. Sleep-disordered breathing was assessed by 18-channel in-laboratory polysomnography and characterized by the apnea-hypopnea index. Setting: Polysomnography was conducted at the University of Wisconsin General Clinical Research Center sleep laboratory. Patients and Participants: Participants included 1104 men and women, aged 30 to 60 years, enrolled in the Wisconsin Sleep Cohort Study. Measurements and Results: Associations were modeled using linear and logistic regression, adjusting for body mass index, skinfold measurements, age, sex, and other covariates. Adjusted mean (95% confidence interval) apnea-hypopnea index was 5.3 (4.4, 6.2) events per hour for participants who exercised 0 hours per week; 3.9 (2.8, 5.0) events per hour for those with 1 to 2 hours of exercise; 3.2 (2.2, 4.2) events per hour for those with 3 to 6 hours of exercise; and 2.8 (1.0, 4.6) for those with > 7 hours of exercise (P trend 15 events per hour) significantly decreased with increasing level of exercise. Conclusion: Independent of measures of body habitus, lack of exercise was associated with increased severity of sleep-disordered breathing. Citation: Peppard PE; Young T. Exercise and sleep-disordered breathing: an association independent of body habitus.
183 citations
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TL;DR: What is known about changes in sleep physiology and behaviour during the perinatal period is reviewed, with a focus on the relations between sleep and postpartum "blues," depression and psychosis and on sleep-based interventions for the treatment and prevention ofPerinatal mood disorders.
Abstract: Pregnancy and the postpartum period are recognized as times of vulnerability to mood disorders, including postpartum depression and psychosis. Recently, changes in sleep physiology and sleep deprivation have been proposed as having roles in perinatal psychiatric disorders. In this article we review what is known about changes in sleep physiology and behaviour during the perinatal period, with a focus on the relations between sleep and postpartum "blues," depression and psychosis and on sleep-based interventions for the treatment and prevention of perinatal mood disorders. The interaction between sleep and perinatal mood disorders is significant, but evidence-based research in this field is limited. Studies that measure both sleep and mood during the perinatal period, particularly those that employ objective measurement tools such as polysomnography and actigraphy, will provide important information about the causes, prevention and treatment of perinatal mood disorders.
183 citations
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TL;DR: It is concluded that daytime sympathetic nervous activation is greater with more severe sleep apnea, and CPAP treatment diminished the daytime sympathetic activation.
183 citations
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TL;DR: These results confirm the similarities in clinical presentation and natural history of narcolepsy-cataplexy in a large number of patients of various ethnic groups and cultural backgrounds.
Abstract: Study Objectives: The objectives of this study were to compare severity and clinical presentation for narcolepsy-cataplexy across various ethnic groups. A large sample of narcoleptic patients was also used to further describe symptomatology and natural history for this sleep disorder. Design: Retrospective review of clinical data ascertained from the Stanford Sleep Inventory, polysomnography and MSLT data, as well as clinical notes. Ethnicity was narrowly defined as African (Black) Americans, Caucasians, Asians, and Latinos when both parents and the subject identified with a given ethnic group. Setting: N/A Participants: We compared the severity and clinical presentation of narcolepsy in 64 African Americans, 353 Caucasians, 32 Asians, 26 Latinos, and 9 subjects of mixed ethnicity. Subjects were recruited through the Stanford center for narcolepsy research. Interventions: N/A Measurements and Results: A striking similarity in symptomatology, age of onset, and disease severity was found across ethnic groups. Mean age of onset for sleepiness, hypnagogic hallucinations, sleep paralysis and cataplexy were 19.20, 19.50, 20.11 and 23.02 years old. We also found that narcoleptic patients have slightly but significantly elevated body mass index relative to normative data (106.6% of matched controls, p<0.005) and are born slightly more frequently during the month of March. A tight correlation between our previously validated cataplexy scale and DQB1 * 0602 positivity was observed. Two thirds of patients reported having cataplexy with laughing, 92% of those being DQB1 * 0602 positive independent of ethnicity. Conclusions: These results confirm the similarities in clinical presentation and natural history of narcolepsy-cataplexy in a large number of patients of various ethnic groups and cultural backgrounds.
182 citations
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TL;DR: The frequency and severity of sleep apnea in the sleep clinic population is greater in men than women, and factors other than NC, age, and BMI must contribute to these gender differences.
182 citations