Potassium dichromate

About: Potassium dichromate is a research topic. Over the lifetime, 1430 publications have been published within this topic receiving 18967 citations. The topic is also known as: Potassium dichromate(VI) & Chromium potassium oxide.

Neuroprotective effect of sodium alginate against chromium-induced brain damage in rats

Abstract: Oral exposure to chromium hexavalent [Cr(VI)] has disastrous impacts and affects many people worldwide. Cr(VI) triggers neurotoxicity via its high oxidation potential by generating high amount of ROS. Meanwhile, alginates are known by their chelating activity and ability to bind heavy metals and toxins, in addition to their antioxidant, anti-inflammatory, and anti-apoptotic activities. So, this study aimed to explore the neuroprotective potential of sodium alginate (SA) against cellular injury, DNA damage, macromolecule alterations, and apoptosis induced by oral ingestion of Cr. Forty Wistar male rats were divided into 4 groups; group I: standard control ingested with the vehicle solution, group II: Cr-intoxicated group received 10 mg/kg b.w. of potassium dichromate orally by gavage and kept without treatment, group III: SA group in which rats were orally exposed to 200 mg/kg b.w. of SA only, and group IV: SA-treated group that received 200 mg/kg b.w. of SA along with Cr for 28 consecutive days. Neurotransmitters such as Acetyl choline esterase (AchE), Monoamine oxidase A (MAOA) concentrations, Dopamine (DA) and 5-Hydroxytryptamine (5-HT) levels were assessed in brain homogenate tissues. Neurobiochemical markers; NAD+ and S100B protein were investigated in the brain tissues and serum, respectively. Levels of HSP70, caspase-3, protein profiling were evaluated. DNA damage was determined using the Comet assay. Results revealed a significant reduction in the AchE and MAOA concentrations, DA, 5-HT, and NAD+ levels, with an increase in the S100B protein levels. Cr(VI) altered protein pattern and caused DNA damage. High levels of HSP70 and caspase-3 proteins were observed. Fortunately, oral administration of SA prevented the accumulation of Cr in brain homogenates and significantly improved all investigated parameters. SA attenuated the ROS production and relieved the oxidative stress by its active constituents. SA can protect against cellular and DNA damage and limit apoptosis. SA could be a promising neuroprotective agent against Cr(VI)-inducing toxicity.

Synthesis, spectroscopic characterisation and X-ray structure of [trans-Co(en)2(NO2)2]2(Cr2O7)

Abstract: Dark red crystals of bis[trans-dinitrobis(ethylenediamine)cobalt(III)] dichromate, [trans-Co(en)2(NO2)2]2(Cr2O7) have been obtained by slowly allowing to mix the solutions of potassium dichromate and trans-dinitrobis(ethylenediamine)cobalt(III) nitrate in 1:2 molar ratio in aqueous medium. Elemental analyses and spectroscopic techniques (IR, UV/visible, 1H and 13C NMR) were used for characterizing the complex salt. The complex salt crystallizes in the orthorhombic space group Fdd2 with unit cell dimensions a = 24.778(2) A, b = 30.457(2) A, c = 6.5364(5) A, Z = 8, V = 4932.8(7) A3, R1 = 0.0617 and wR2 = 0.1518. X-ray structure determination revealed an ionic structure consisting of cationic cobaltammine [trans-Co(en)2(NO2)2]NO3 and dichromate anion. It is the first crystal structure of this cation with a dianion.

Wood-treatment compositions

Abstract: 1,136,082. Preserving wood. HICKSON'S TIMBER IMPREGNATION CO. (GB) Ltd. 27 Jan., 1966 [22 Feb., 1965], No. 7565/65. Heading A5E. [Also in Divisions B1 and Dl] An aqueous wood impregnant contains 0.1-3% of dispersed paraffin wax of mp 40-50‹C, 0.008-0.36% of a non-ionic wax emulsifying agent, and 1-10% of a preservative. The emulsifying agent is a condensate of a C 10-18 fatty alcohol or a C 7-11 alkyl phenol, has one or more polyoxyethylene chains containing at least 25 ethylene oxide units and has a hydrophilic balance of 12-22. The preservative may be a composition containing sodium fluoride, arsenic pentoxide, sodium arsenate, sulphate or arsenate of copper or zinc, chromic acid, sodium chromate, or sodium or potassium dichromate. The composition may also contain monoammonium or diammonium phosphate, ammonium sulphate, boric acid, or sodium tetraborate as fire retardants. It may also contain petroleum jelly of mp 38-56‹C in a ratio of wax to jelly of 45:55 to 70:30. The wood may be impregnated by the alternate application of pressure and vacuum.

Kinetic and mechanistic study of oxidation of ester by K2Cr2O7

Abstract: In present investigation we are studied the kinetics and mechanism of oxidation of ester by potassium dichromate in acid medium. In the present paper we reported the effect of oxidant K2Cr2O7, effect of substrate (ester), effect of sulphuric acid and effect of temperature on oxidation of ester. The reaction is first order with respect to oxidant and substrate, as temperature increases rate of the reaction also increases