Topic
Potassium dichromate
About: Potassium dichromate is a research topic. Over the lifetime, 1430 publications have been published within this topic receiving 18967 citations. The topic is also known as: Potassium dichromate(VI) & Chromium potassium oxide.
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TL;DR: A reliable Golgi-Kopsch variant is described and procedures for cutting, counterstaining, and handling sections are described.
53 citations
TL;DR: The study suggests that PYC is effective in preventing K2Cr2O7-induced oxidative mediated nephrotoxicity, but more studies are needed to confirm the effects of PYC as a nephroprotective agent.
53 citations
TL;DR: The analyses of A. thaliana transgenic plants that express the auxin-inducible marker DR5:uidA, and the response of the Auxin-resistant mutants axr2 and aux1‐7 to dichromate suggest that auxins do not participate as mediators in the cellular and physiological responses to this metal.
53 citations
TL;DR: It is suggested that the defence system of sea bass red blood cells against active oxygen species can be compromised by metal ions, this imbalance being able to cause increased membrane lipid peroxidation.
53 citations
TL;DR: It is concluded that the DTPA‐cream clearly abrogates positive patch test reactions in nickel‐, cobalt‐ and copper‐sensitized subjects and that it may therefore be helpful in the management of allergic contact dermatitis.
Abstract: Chelating agents in protective barrier creams have often been used in the prevention of allergic contact dermatitis to nickel. In a pilot study, we demonstrated the preventive effect of 10% diethylenetriaminepentaacetic acid (DTPA) in an oil-in-water emulsion in nickel-sensitized patients. Now we reproduced these results in a randomized, double-blind study. Additionally, we investigated the efficacy of the barrier cream in other clinically relevant metal allergies. Individuals sensitized to various metals had a significant decrease in positive patch test reactions after pre-treatment with the DTPA-cream: 2.5% nickel sulfate (24/28 positive without pre-treatment versus 1/28 with pre-treatment; p<0.0001), 5% nickel sulfate (30/32 versus 15/32; p=0.0003), 1% cobalt chloride (19/20 versus 6/20; p=0.001) and 5% copper sulfate (13/14 versus 5/14; p=0.02). However, the cream had no protective effect with 1% palladium chloride (17/23 versus 16/23) and with 0.5% potassium dichromate (9/13 versus 7/13). We conclude that the DTPA-cream clearly abrogates positive patch test reactions in nickel-, cobalt- and copper-sensitized subjects and that it may therefore be helpful in the management of allergic contact dermatitis.
53 citations