Potassium dichromate

About: Potassium dichromate is a research topic. Over the lifetime, 1430 publications have been published within this topic receiving 18967 citations. The topic is also known as: Potassium dichromate(VI) & Chromium potassium oxide.

The role of eugenol in the prevention of chromium-induced acute kidney injury in male albino rats

Abstract: Background Potassium dichromate induces nephrotoxicity mainly due to increased cellular oxidative stress. Objectives To evaluate the possible renoprotective effects of eugenol on the damage induced by potassium dichromate poisoning in male rats. Methods 30 male Wistar rats were divided into 3 groups, 10 rats in each group; Control group: given olive oil orally (5 mL/kg body weight) for 10 consecutive days. Potassium dichromate (PDC) group: received olive oil orally (5 mL/kg body weight) for 10 consecutive days, then a single s.c. injection of PDC (15 mg/kg) was given in the tenth day. And eugenol + PDC group: received eugenol orally (100 mg/kg body weight/day) for 10 consecutive days and a single s.c. injection of PDC (15 mg/kg) in the tenth day. Then the animals were anaesthetized, blood samples were taken from the abdominal aorta, for measurement of serum urea and creatinine, and lactate dehydrogenase (LDH). Also reduced glutathione (GSH), malondialdehyde (MDA), superoxide dismutase (SOD) and tumor necrosis factor alpha (TNF-α) were monitored in renal tissue. Results PDC caused significant increase in serum urea, creatinine and LDH levels; this was accompanied with significant decrease in renal GSH and SOD contents, and increase in renal MDA and TNF-α. Histopathological investigations provoked tubular necrosis associated with mononuclear cell infiltration. Pretreatment of rats with eugenol significantly change all previously mentioned PDC-induced effects. Conclusion The findings of the current study revealed that eugenol protected the kidney against PDC-induced acute kidney injury in rats by its antioxidant and anti-inflammatory properties.

Demethylation of thiolignin by reaction with potassium dichromate — a kinetic study

Abstract: Lignin is sufficiently reactive to undergo significant reactions with other polymerizing agents. In this work the activation of thiolignin with potassium dichromate has been studied. 10.3% of OCH3 groups were demethylated in 168 h in the presence of acetic acid. Only 1.1% OCH3 groups were demethylated in the time from 20 min to 3 h. The ratio of phenolic OH/OCH3 increases in the 1st stage from 0.493 to 1.74 and decreases in the second stage to 1.55 and then again greatly increases in the third stage to 10. At this stage almost complete demethylation of thiolignin occurred. The kinetics of the reaction between thiolignin and potassium dichromate has been described.