Showing papers on "Potassium iodate published in 2003"

Fast Colorimetric Method for Measuring Urinary Iodine

Abstract: International groups recommend the following median urinary iodine concentration as the best single indicator of iodine nutrition in populations: severe deficiency, 0–0.15 μmol/L (0–19 μg/L); moderate deficiency, 0.16–0.38 μmol/L (20–49 μg/L); mild deficiency, 0.40–0.78 μmol/L (50–99 μg/L); optimal iodine nutrition, 0.79–1.56 μmol/L (100–199 μg/L); more than adequate iodine intake, 1.57–2.36 μmol/L (200–299 μg/L); and excessive iodine intake, ≥2.37 μmol/L (≥300 μg/L) (1). The range in which the median falls is more important than the precise number (2)(3). Many methods for assessing urinary iodine exist (3)(4)(5)(6)(7)(8), most based on the Sandell–Kolthoff reaction (9), in which iodide catalyzes the reduction of ceric ammonium sulfate (yellow) to the colorless cerous form in the presence of arsenious acid. Although iodide is the chemical form for both the catalytic reaction and in urine, some preliminary treatment is needed to rid urine of impurities, most commonly by acid digestion (3)(5). We have extended previous approaches (5)(6)(10) with improved conditions and here present a new method (“Fast B”) that is rapid, inexpensive, reliable, and flexible. The equipment required for the Fast B method includes a heating block, Pyrex test tubes (13 × 100 mm), two fixed-volume pipettes (0.5 mL and 1.0 mL), one adjustable pipette (0–200 μL), and a multipet (Eppendorf) for quick reagent volume additions of 0.125 and 0.1 mL. The basic chemicals used are potassium iodate, arsenic trioxide, ammonium persulfate, ammonium cerium(IV) sulfate dihydrate, sodium chloride, ferroine, and sulfuric acid. The solutions used in the assay are as follows:

Spray formulation of providone iodine

Abstract: The present invention discloses one kind of Povidone-iodine spraying agent, and features that the Povidone-iodine spraying agent consists of active component Povidone-iodine, potassium iodate and/or potassium iodide, glycerine and/or propylene glycol, corrective and water It is stable in quality, has no irritation to skin and mucous membrane and is suitable for oral taking to prevent and treat bacterial, fungal and viral infection

Characterization of sulfur speciation in low molecular weight subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values using x-ray absorption near-edge structure (XANES) spectroscopy.

Abstract: Sulfur speciation in low molecular weight (LMW) subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values, aged subunits of glutenin as well as gluten, and gliadin have been investigated in situ by S K-edge X-ray absorption near-edge structure (XANES) spectroscopy XANES spectra were analyzed quantitatively using a least-squares fitting routine to provide relative percentage contribution of different sulfur species occurring in the samples Using potassium iodate and potassium bromate for reoxidation of reduced LMW subunits of glutenin led not only to disulfide states but also to higher oxidation states (sulfoxide state, sulfonic acid state) Strongest oxidation occurred at low pH values Higher oxidation states were also predominantly detected in the aged subunits of glutenin, whereas the disulfide state was the main sulfur species in gluten and gliadin samples The results showed that the oxidation state of sulfur prior to oxidation (thiol, disulfide) strongly influences sulfur speciation after oxidation The choice of the oxidizing reagent seems to be of minor importance

Spectrophotometric determination of cephalosporins with leuco crystal violet

Abstract: A simple and sensitive spectrophotometric method for the determination of cefotaxime, ceftriaxone and cefradine with leuco crystal violet is presented. The determination is based on the reduction of potassium iodate in acidic medium, followed by hydrolysis of β-lactam ring of cephalosporins with sodium hydroxide. The formed iodine reacts with leuco crystal violet. The crystal violet dye of maximum absorption at 588 nm is formed. Its absorbance was measured within pH range of 4.0-4.2 in 1 cm cuvettes. Beer's law was obeyed in the concentration range: 0.8-4.8 μg mL - 1 , 0.4-1.6 μg mL - 1 and 0.2-2.0 μg mL - 1 for cefotaxime, ceftriaxone and cefradine, respectively. The molar absorptivity of the coloured compound is 8.4 × 10 4 L mol - 1 cm - 1 for cefotaxime, 2.4 x 10 5 L mol - 1 cm - 1 for ceftriaxone and 1.6 x 10 5 L mol - 1 cm - 1 for cefradine. The analytical parameters were optimized and the method was successfully applied to the determination of cefotaxime, ceftriaxone and cefradine in pharmaceuticals.

Four simple procedures for the assay of methdilazine in bulk drug and in tablets and syrup using potassium iodate.

Abstract: Four simple, selective, accurate and reproducible procedures are described for the assay of methdilazine in bulk form and in formulations. One titrimetric and three spectrophotometric methods are based on the oxidation of the drug with potassium iodate, and determination of either excess iodate or iodine released in the reaction. In the titrimetric method (Method A) the drug is reacted with a known excess of iodate in sulphuric acid medium followed by the iodometric determination of residual oxidant. The residual oxidant is determined by reacting it with variamine blue and measuring the absorbance of the oxidised dye at 540 nm (Method B). The second spectrophotometric method (Method C) is based on the oxidation of the drug in sulphuric acid medium in the presence of chloride ions by a large excess of iodate and the iodate being reduced to iodine. The ICl 2 − generated in this reaction is used to iodinate 2′,7′-dichlorofluorescein dye, and the red colour of the iodinated dye is measured at 525 nm. The other spectrophotometric method (Method D) also involves the oxidation of the drug in acid medium by a large excess of iodate with the liberation of iodine and its subsequent extraction with carbon tetrachloride followed by measuring the absorbance 520 nm. The methods were successfully applied to the determination of methdilazine in tablets and syrup and the results obtained in agreement with the label claim.

Correction of iodine deficiency in Macedonia.

Abstract: A national survey conducted in 1995-96 showed that mild to moderate iodine deficiency existed in Macedonia (median urinary iodine [UI] concentration 117 microg/l). It was concluded that a new legal regulation should be introduced concerning the iodination of table salt for human consumption. The iodine level was recommended to be 20-30 mg/kg salt, exclusively in the form of the more stable potassium iodate. The new regulations were instituted and became effective in October, 1999. National surveys performed in 2000 and 2001 showed increased median UI concentrations (154.1 microg/l in 2000 and 164.5 microg/l in 2001). In 2001, UI excretion was assessed in 490 pregnant and lactating women (median UI concentration 140 microg/l). During the last three surveys, household salt specimens were assessed for iodine content. The findings showed an increase of the percentage of the optimal iodine content in household salt (42-69%), which correlated with the higher IU excretion results. The new regime of salt iodination was proved to be highly effective in correcting the iodine deficiency in Macedonia.

Oxidimetric determination of captopril using potassium iodate

Abstract: Two simple and accurate methods are described for captopril determination. The titrimetric method involves the oxidation of the drug with a known excess of iodate and titration of the unreacted oxidant iodometrically. Thespectrophotometric method is based on the oxidation of the S-atom of the drug with a large excess of iodate in sulphuric acid medium and measurement of the iodine released, at 460 nm. Reaction conditions are optimised. Titrimetry is applicable over 1-12 mg range whereas spectrophotometry can be used to determine captopril in the concentration range 50-400 μg ml - 1 with an apparent molar absorptivity of 0.38 x 10 3 1 mol - 1 cm - 1 and a Sandell sensitivity of 0.578 μg cm - 2 . The methods were highly reproducible with a relative standard deviation of less than 2%. Proprietary drugs containing captopril were analysed by the proposed methods successfully with no interference from tablet excipients.

Sporting drink containing sugar, electrolyte and microelement

Abstract: The invention relates to a sport beverage containing sugar, electrolyte and microelement, wherein each 100 ml of the beverage contains sodium chloride 0.8-1.2g, or glucose, cane sugar, or refined white sugar 4.8-10.4g, or potassium iodate 2-200 microgram, calcium gluconate (or calcium carbonate) 4-200 mg, ferrous gluconate 0.1-2.4 mg, gluconic acid 0.1-4mg, sodium selenite 0.6-40 microgram, gluconic acid 0.02-20 mg, potassium gluconate 0.2-10 mg.

Colorimetric Determination of Sulphur Dioxide and Sulphites in Various Environmental Samples

Abstract: Rhodamine-B has been proposed as a simple and sensitive colorimetric reagent for the estimation of sulphur dioxide in air. The air sample containing sulphur dioxide is passed through the absorbing solution of aqueous potassium iodate and N-chlorosuccinimide to liberate iodine. The liberated iodine bleaches the pinkish red coloured rhodamine-B dye, which measured at 555 nm. Beer's law was obeyed in the range of 0.5-5.0 μg, of sulphite per 25 mL (0.02-0.2 ppm) equivalent to 0.4-4.0 μg of sulphur dioxide (0.016-0.16 ppm). The molar absorptivity and Sandell's sensitivity were found to be 4.56 × 10 5 1 mol - 1 cm - 1 and 0.00017 μg cm - 2 , respectively. The method has been suitably modified and successfully applied to the determination of sulphites in water after liberation of sulphur dioxide in acidic medium.

A New, Environment Friendly Protocol for Iodination of Electron‐Rich Aromatic Compounds.

Abstract: A new environment friendly procedure for effective aromatic iodination is presented. A mixture of potassium iodide and potassium iodate is used in the presence of an acid for in situ iodination of aromatic compounds.

Determination of Iodine in Edible Salt Added Potassium Iodate by Ultraviolet Spectrophotometry

Abstract: According to the ultraviolet absorption spectra of iodine,iodide ion and triiodide ion, a method for determination of iodine in edible salt added potassium iodate was proposed. In the medium of HCl with pH 2.4, 0.01?mol/L KI, 1 mol potassium iodate may be quantitatively converted into 3?mol I 3-.By measuring the absorbance of I 3- at 288 or 350 nm, quantity of iodine in edible salt can be calculated. A recovery percent of this method was found to be 96.8?%～102.6?%. Two samples of edible salt purchased from market were analyzed. The results were satisfactory.

Solubility of lead iodate in aqueous systems

Abstract: Two forms of lead iodate, with different crystalline structures and solubilities in water, have been reported. Previous workers have found that when the compound is prepared from dilute solution with a slight excess of lead nitrate one form is produced at 25 °C and the other at 60 °C. In this study, relative excesses of lead nitrate or potassium iodate during precipitation were found to have more influence than temperature on the form produced. Solubilities in water at various temperatures and in several aqueous systems at room temperature have been determined. Photomicrographs and X-ray data have also been obtained.

Potassium iodate production process (options)

Abstract: FIELD: industrial inorganic synthesis. SUBSTANCE: invention relates to processing of hydromineral raw materials, in particular to processing of iodine- containing waters, and aims to reduce process cycle and to increase desired product yield. Elementary iodine is made react with potassium hydroxide to form potassium iodate and potassium iodide both dissolved in reaction milieu having alkalinity up to 8 g/l and containing up to 160 g/l iodide anions and up to 50 g/l iodine cations. Reaction milieu is subjected to electrolysis and then concentrated at temperature no lower than 80 C, after which follows crystallization caused by cooling of reaction milieu to ambient temperature and isolation of desired product crystals. Optionally, electrolysis of reaction milieu can be accompanied by potassium iodide oxidation. EFFECT: reduced process time. 4 cl, 2 ex

Preparation of Harris hematoxylin without use of mercury oxide

Abstract: The study was carried out with the aim of improvement of Harris' alum hematoxylin formula. In presented modified formula toxic mercuric oxide (2.5 g) is substituted by potassium iodate (0.55 g). Alum hematoxylin solution prepared according to suggested formula retains high quality of original Harris' hematoxylin.

Four simple methods for the determination of famotidine in bulk form and formulations.

Abstract: Four simple, rapid and reliable methods were developed for the assay of famotidine in bulk form and in formulations. The titrimetric method (A) is based on the oxidn. of the drug by a known excess of potassium iodate in acid medium and detn. of the residual oxidant by iodometric back titrn. with thiosulfate. Three spectrophotometric procedures also involve the oxidn. of the drug by iodate. One procedure (B) is based on iodometric detn. of the excess iodate by an auxiliary reaction using variamine blue dye. The other two spectrophotometric procedures are based on the measurement of iodine formed in the redox reaction involving famotidine and iodate. In procedure C, iodine formed is oxidized to ICl2- in the presence of chloride ions. It is used to iodinate 2,4-dichlorofluorescein dye and the iodinated dye is measured at 520 nm, whereas the iodine released is extd. into carbon tetrachloride and measured at 520 nm in method D. Reaction conditions were optimized. The procedures described were successfully applied to the detn. of famotidine in its pharmaceutical formulations. [on SciFinder(R)]

Synthesis of N,N-Diaryl-N′-N′-1,4-phenylenedi(oxyacetyl)dithioureas and Corresponding Diureas.

Abstract: N,N-Diaryl-N′,N′-1,4-phenylenedi(oxyacetyl)-dithioureas (3a–l) are synthesized under solid–liquid phase transfer catalysis. Meanwhile, the corresponding diureas of 3a–l, N,N-Diaryl-N′,N′-1,4-phenylenedi(oxyacetyl)-diureas (4a–l), are further synthesized by the reaction of 3a–l with potassium iodate in high yield.

Inhibitory kinetic-fluorimetric determination of trace aniline

Abstract: A novel inhibitory kinetic-fluorimetric method is reported for the determination of trace aniline. The method is based on the inhibitory effect of aniline on the oxidation of rhodamine B by potassium iodate in hydrochloric acid. The detection limit for aniline is 0.872 ng/mL; the linear range of determination is 4.10∼41.0 ng/mL. Every parameter has been optimized. Some ions which seriously interfere with the determination can be removed by means of pre-distillation in basic condition. The proposed method is simple, rapid and reliable. It has been applied to the determination of trace aniline in waste and tap waters.