Topic
Primate
About: Primate is a research topic. Over the lifetime, 1250 publications have been published within this topic receiving 67388 citations. The topic is also known as: the primate order & primates.
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TL;DR: The arrangement of alpha-globin genes in Old World and New World monkeys and a prosimian, galago, has been determined by restriction mapping and Orthologous Alu family members in human and monkey DNAs indicate that the dispersion of some Alu repeats occurred prior to the divergence of these lineages.
44 citations
TL;DR: Tests on chimpanzees, orangutans, gibbons, baboons, and a gorilla, with blood grouping reagents prepared for human red cells, have disclosed patterns of reactions characteristic of each primate species.
Abstract: Tests on chimpanzees, orangutans, gibbons, baboons, and a gorilla, with blood grouping reagents prepared for human red cells, have disclosed patterns of reactions characteristic of each primate species. Determinations have been made of A-B-O groups and subgroups, M-N types, Rh-Hr types, secretor status, and Lewis types. Immunization experiments with ape and monkey blood are in progress.
44 citations
TL;DR: It is shown that the apparent binding affinity of the glucocorticoid receptor in squirrel monkey lymphocytes is 5-fold lower than that in human lymphocytes, consistent with previous studies in mononuclear leukocytes isolated from the two species.
Abstract: New World primates such as the squirrel monkey have elevated cortisol levels and glucocorticoid resistance We have shown that the apparent binding affinity of the glucocorticoid receptor in squirrel monkey lymphocytes is 5-fold lower than that in human lymphocytes (apparent Kd, 209 ± 18 and 43 ± 02 nmol/L, respectively; n = 3), consistent with previous studies in mononuclear leukocytes isolated from the two species As a first step in understanding the mechanism of decreased binding affinity in New World primates, we used reverse transcription-PCR to clone the glucocorticoid receptor from squirrel monkey liver and have compared the sequence to receptor sequences obtained from owl monkey liver, cotton-top tamarin B95-8 cells, and human lymphocytes The squirrel monkey glucocorticoid receptor is approximately 97% identical in nucleotide and amino acid sequence to the human receptor The ligand-binding domain (amino acids 528–777) of the squirrel monkey glucocorticoid receptor contains four amino acid d
44 citations
TL;DR: Monkeys (Macaca) were trained by operant conditioning techniques to report the minimum detectable change in location of a sound in space, and were tested with a series of recorded coo or clear call vocalizations, finding acuity of localization varied from approximately 4 degrees to 15 degrees.
Abstract: Monkeys (Macaca) were trained by operant conditioning techniques to report the minimum detectable change in location of a sound in space, and were tested with a series of recorded coo or clear call vocalizations. Acuity of localization varied from approximately 4 degrees to 15 degrees and was a function of the magnitude of the change in pitch (frequency modulation) of the different clear calls.
44 citations
TL;DR: The primate and rodent models developed in the present study will be useful for the study of the immunology and chemotherapy of onchocerciasis.
Abstract: Third-stage larvae (L3) of Onchocerca volvulus were implanted in diffusion chambers in chimpanzees, mangabey monkeys, rhesus monkeys, squirrel monkeys, and inbred strains of mice, jirds, and rats for 3-63 days. At different times during the experimental period, larvae were recovered and assessed for their viability and development. Survival and growth rates were equal regardless of whether the implanted larvae were fresh or cryopreserved. Survival and growth rates of the larvae did not differ among the primate and rodent hosts tested, with the exception of squirrel monkeys and rats, which were resistant to infection. Molting from L3 to fourth-stage larvae began on day 3 and continued through day 14 in the primates and rodents. The primate and rodent models developed in the present study will be useful for the study of the immunology and chemotherapy of onchocerciasis.
44 citations