scispace - formally typeset
Topic

Probiotic

About: Probiotic is a(n) research topic. Over the lifetime, 9024 publication(s) have been published within this topic receiving 304058 citation(s). The topic is also known as: PBX & probiotic.

...read more

Papers
  More

Journal ArticleDOI: 10.1093/JN/125.6.1401
Glenn R. Gibson, Marcel Roberfroid1Institutions (1)
Abstract: Because the human gut microbiota can play a major role in host health, there is currently some interest in the manipulation of the composition of the gut flora towards a potentially more remedial community. Attempts have been made to increase bacterial groups such as Bifidobacterium and Lactobacillus that are perceived as exerting health-promoting properties. Probiotics, defined as microbial food supplements that beneficially affect the host by improving its intestinal microbial balance, have been used to change the composition of colonic microbiota. However, such changes may be transient, and the implantation of exogenous bacteria therefore becomes limited. In contrast, prebiotics are nondigestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of one or a limited number of bacterial species already resident in the colon, and thus attempt to improve host health. Intake of prebiotics can significantly modulate the colonic microbiota by increasing the number of specific bacteria and thus changing the composition of the microbiota. Nondigestible oligosaccharides in general, and fructooligosaccharides in particular, are prebiotics. They have been shown to stimulate the growth of endogenous bifidobacteria, which, after a short feeding period, become predominant in human feces. Moreover, these prebiotics modulate lipid metabolism, most likely via fermentation products. By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.

...read more

Topics: Synbiotics (69%), Prebiotic (63%), Galactooligosaccharide (62%) ...read more

6,687 Citations


Open accessJournal ArticleDOI: 10.1111/J.1365-2672.1989.TB05105.X
Abstract: There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease. However, the composition of this protective flora can be altered by dietary and environmental influences, making the host animal susceptible to disease and/or reducing its efficiency of food utilization. What we are doing with the probiotic treatments is re-establishing the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy. These are all areas where the gut flora can be altered for the worse and where, by the administration of probiotics, the natural balance of the gut microflora can be restored and the animal returned to its normal nutrition, growth and health status.

...read more

Topics: Gut flora (57%), Flora (56%), Probiotic (53%)

4,055 Citations


Open accessJournal Article
Abstract: There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease. However, the composition of this protective flora can be altered by dietary and environmental influences, making the host animal susceptible to disease and/or reducing its efficiency of food utilization. What we are doing with the probiotic treatments is re-establishing the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy. These are all areas where the gut flora can be altered for the worse and where, by the administration of probiotics, the natural balance of the gut microflora can be restored and the animal returned to its normal nutrition, growth and health status.

...read more

Topics: Gut flora (57%), Flora (56%), Probiotic (53%)

3,276 Citations


Journal ArticleDOI: 10.1016/J.TIFS.2003.09.004
Frédéric Leroy1, Luc De Vuyst1Institutions (1)
Abstract: The production of fermented foods is based on the use of starter cultures, for instance lactic acid bacteria that initiate rapid acidification of the raw material. Recently, new starter cultures of lactic acid bacteria with an industrially important functionality are being developed. The latter can contribute to the microbial safety or offer one or more organoleptic, technological, nutritional, or health advantages. Examples are lactic acid bacteria that produce antimicrobial substances, sugar polymers, sweeteners, aromatic compounds, vitamins, or useful enzymes, or that have probiotic properties.

...read more

Topics: Fermentation starter (61%), Lactic acid (57%), Fermentation in food processing (51%) ...read more

1,399 Citations


Open accessJournal ArticleDOI: 10.1079/BJN19980108
Abstract: The gut is an obvious target for the development of functional foods, acting as it does as the interface between diet and the metabolic events which sustain life. The key processes in digestive physiology which can be regulated by modifying diet are satiety, the rate and extent of macronutrient breakdown and absorption from the small bowel, sterol metabolism, the colonic microflora, fermentation, mucosal function and bowel habit, and the gut immune system. The intestinal microflora is the main focus of many current functional foods. Probiotics are foods which contain live bacteria which are beneficial to health whilst prebiotics, such as certain non-digestible oligosaccharides which selectively stimulate the growth of bifidobacteria in the colon, are already on the market. Their claimed benefits are to alleviate lactose maldigestion, increase resistance to invasion by pathogenic species of bacteria in the gut, stimulate the immune system and possibly protect against cancer. There are very few reports of well-designed human intervention studies with prebiotics as yet. Certain probiotic species have been shown to shorten the duration of rotavirus diarrhoea in children but much more work is needed on the mechanism of immunomodulation and of competitive exclusion and microflora modification. The development of functional foods for the gut is in its infancy and will be successful only if more fundamental research is done on digestive physiology, the gut microflora, immune system and mucosal function.

...read more

Topics: Gut flora (62%), Gastrointestinal function (55%), Probiotic (52%) ...read more

1,374 Citations


Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202218
2021763
2020744
2019728
2018644
2017649

Top Attributes

Show by:

Topic's top 5 most impactful authors

Seppo Salminen

60 papers, 5.8K citations

Arthur C. Ouwehand

55 papers, 5K citations

Amir Mohammad Mortazavian

37 papers, 1.3K citations

Jorge Alberto Reinheimer

26 papers, 2.1K citations

Nagendra P. Shah

26 papers, 2.9K citations

Network Information
Related Topics (5)
Lactobacillus

13.3K papers, 399.4K citations

93% related
Lactobacillus acidophilus

6.7K papers, 194K citations

92% related
Lactobacillus plantarum

9K papers, 194.7K citations

91% related
Lactobacillus casei

5.6K papers, 151.5K citations

90% related
Bifidobacterium

4.1K papers, 196.9K citations

90% related