Topic
Prolactin
About: Prolactin is a research topic. Over the lifetime, 22356 publications have been published within this topic receiving 609537 citations. The topic is also known as: lactotropin, & PRL,.
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TL;DR: In primates, as in rodents, systemically administered NMA is capable of eliciting pituitary hormone secretion, although the site of its action in the rhesus monkey remains to be established.
109 citations
TL;DR: High extracellular K+ concentrations that prevent dopamine effects on membrane potential and [Ca2+]i, but not cAMP levels, completely blocked dopamine regulation of the prolactin promoter, which suggests that two distinct signaling pathways initiated at D2 receptors may be required for transcriptional regulation.
109 citations
TL;DR: NPY seems to exert a selective effect on LH release, and it might be hypothesized that NPY could affect LHRH release in two areas which lack blood-brain barrier: the organum vasculosum of the lamina terminalis (OVLT) which contains LHRh cell bodies and NPY fibers and the median eminence which contains both L HRH andNPY fibers.
109 citations
TL;DR: Addition of CaCl2 to GH3 cells incubated in a serum-free, Ca2+-free medium increased relative prolactin synthesis 7- to 150-fold by 3-4 days, but had no effect on relative growth hormone synthesis.
109 citations
TL;DR: It is concluded that renal transplantation corrects the hyperprolactinemia induced by uremia and is followed by rapid onset of restoration of the hypothalamic-pituitary-gonadal axis.
Abstract: Background: Chronic renal failure is commonly associated with disturbances in hypothalamic-pituitary-gonadal function. Methods: The gonadotrophins, prolactin and
108 citations