Showing papers on "Protoporphyrins published in 1985"
TL;DR: Tin(IV)‐protoporphyrin chloride is a potent photosensitizer of bilirubin destruction in vitro at visible wavelengths (410, 540, 580 nm) and it is speculated that the drug may have phototoxic effects in vivo if it accumulates in light‐accessible tissues.
Abstract: — Tin(IV)-protoporphyrin chloride, a proposed chemotherapeutic agent for prevention of neonatal hyperbilirubinemia, is a potent photosensitizer of bilirubin destruction in vitro at visible wavelengths (410, 540, 580 nm). We speculate that the drug may have phototoxic effects in vivo if it accumulates in light-accessible tissues.
31 citations
TL;DR: In blood samples taken from patients suffering from acute inflammatory processes the mean ZPP level was twofold higher, and the mean FPP was four times higher, than the normal level, suggesting better sensitivity of the FPP measurement for the detection of minor influences on the hemopoietic system.
10 citations
TL;DR: In this paper, total syntheses of hemins with permutations of the propionic side-chains in the C and D rings (compared with protoporphyrin-IX) are described.
6 citations
TL;DR: In this article, the Raman spectra of the nickel protoporphyrin polymer films show that vinyl groups are saturated in the polymer as evidenced by the disappearance or shifts in vinyl-dependent vibrations.
Abstract: Free acid Cu, Ni, and Zn, but not Fe(III) and Sn(OH)/sub 2/, protoporphyrins IX have been oxidatively polymerized via the ring vinyl substituents onto electrode surfaces. Electropolymerization follows a ring oxidation mechanism as previously observed for the protoporphyrin dimethyl esters. Raman spectra of the nickel protoporphyrin polymer films show that vinyl groups are saturated in the polymer as evidenced by the disappearance or shifts in vinyl-dependent vibrations. Appreciable axial ligation of Ni and Cu in the polymer films is also ruled out by the Raman results. Surface enhancement of the Raman scattering is observed for polymer films on silver electrodes but not on platinum and tin oxide electrodes. Differences between the spectra of the first monolayer at the Ag surface and the bulk polymer are slight, but small frequency shifts are detected by applying the Raman difference spectroscopic technique. 24 references, 3 figures, 2 tables.
2 citations