Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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TL;DR: This is the first report of induction of haploidization in Aspergillus nidulans by chloral hydrate, which is an efficient polyploidizing agent for higher plants and a psychotropic drug for man.
Abstract: This is the first report of induction of haploidization inAspergillus nidulans by chloral hydrate, which is an efficient polyploidizing agent for higher plants and a psychotropic drug for man. A new procedure has been described to isolate haploids from diploids with a very high frequency, as compared top-fluorophenylalanine, which is generally used for this purpose.
24 citations
TL;DR: The results indicate the potential for alcohol-related health risks among aging Finnish men and women using psychotropic drugs and men who use anxiolytics and sedatives are more likely to drink alcohol at least twice a week than men not using psychotropics.
24 citations
TL;DR: 3 established psychometric tests that have been shown over a long period of time to be not only valid and reliable measures of aspects of behaviour relevant to the daily activities of patients taking such drugs but also appropriate indicators of any countertherapeutic effects or side effects of medication are focused on.
Abstract: The basic assumption underlying psychopharmacology is that the effects of psychoactive drugs can be assessed by measuring the changes produced on aspects of human behaviour and cognitive function. This review concentrates on 3 established psychometric tests that have been shown over a long period of time to be not only valid and reliable measures of aspects of behaviour relevant to the daily activities of patients taking such drugs but also appropriate indicators of any countertherapeutic effects or side effects of medication. Choice reaction time (CRT) is a reliable index of sedation directly related to accident risk situations at home, on the road or at work. Critical flicker fusion threshold (CFFT), a direct measure of the capacity for processing cognitive information, is an accurate measure of various aspects of mental illness and drug effects, and the continuous daytime EEG (c-EEG) is a truly objective measure of CNS activity on a continuous 24-h basis. The judicious use of CRT, CFFT, CFFT and c-EEG not only demonstrates the inherent potential of certain molecules to adversely affect the performance of certain daily activities but also helps identify the drugs with profiles of activity or side effects that are likely to be countertherapeutic.
23 citations
TL;DR: An assessment has been made of the actions of the psychotropic drug alprazolam and of its possible interaction with alcohol, using a variety of psycho(pharmaco-)logical test systems designed to examine sensory, motor and other central nervous system functions in addition to giving subjects impressions of drug actions and side-effects.
Abstract: An assessment has been made of the actions of the psychotropic drug alprazolam and of its possible interaction with alcohol, using a variety of psycho(pharmaco-)logical test systems designed to examine sensory, motor and other central nervous system functions in addition to giving subjects impressions of drug actions and side-effects. The merits and validity of these tests will be discussed and the simplicity of assessing psychomotor function for investigating drug-alcohol interactions is illustrated.
23 citations