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Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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Journal Article•
TL;DR: Investigation of the prevalence of attention-deficit/hyperactivity disorder and its association with sociodemographic characteristics, comorbid mental disorders, medical services, and methylphenidate use in the Israeli adolescent population finds a substantial proportion of older Israeli adolescents are under-diagnosed or untreated.
Abstract: Background The prevalence of ADHD is controversial, with many feeling that this disorder is over- or under-diagnosed. Objectives To study the prevalence of attention-deficit/hyperactivity disorder (ADHD) and its association with sociodemographic characteristics, comorbid mental disorders, medical services, and methylphenidate use in the Israeli adolescent population. Methods The Israel Survey of Mental Health among Adolescents was conducted in a representative national sample of 14-17 year olds and their mothers. The Development and Well-Being Assessment was administered to identify DSM-IV diagnoses of ADHD and comorbid mental and learning disorders, and the results were verified by senior child psychiatrists. Respondents were also asked about their use of medical services and psychotropic drug intake in the past 12 months. Results Three percent of the adolescents met the DSM-IV criteria for ADHD. ADHD was significantly associated with gender (higher prevalence in boys than girls), ethnicity (higher prevalence in Jews than Arabs/Druze), referral to a medical professional, and maternal help-seeking for the emotional or behavioral problems of the adolescent. Medication was prescribed to 2.9% of adolescents: 34.6% with a diagnosis of ADHD had not been prescribed methylphenidate in the past year, and 34.6% of the medicated subjects did not have a diagnosis of ADHD. None of the Arab/Druze adolescents was receiving stimulants compared to 3.7% of the Jewish adolescents. Conclusions Despite advances in public awareness of mental disorders in youth, a substantial proportion of older Israeli adolescents, especially from minority groups, are under-diagnosed or untreated. At the same time, many, especially from the Jewish majority, are over-diagnosed and potentially over-treated. Ethnic disparities in rates of mental health care highlight the urgent need to identify and overcome barriers to the recognition and treatment of these conditions.
21 citations
TL;DR: The results indicate that only 46.9% of the older adults with a diagnosis of depression or anxiety during the 24-month period studied according to the RAMQ register used antidepressants (AD) on average, and the number of days of AD and benzodiazepine use was not associated with partial or total remission.
Abstract: Objective:To document the use of psychotropic drugs in Quebec older adult population with a depressive or anxiety disorder.Method:Data from the Enquete sur la Sante des Aines (ESA) study conducted ...
21 citations
TL;DR: In rats conditioned on an FR 25 schedule with a 10 sec time out, various dose levels of chlordiazepoxide produced significant increases in response rates during CS and in responses during time out.
Abstract: In rats conditioned on an FR 25 schedule with a 10 sec time out, various dose levels of chlordiazepoxide produced significant increases in response rates during CS and in responses during time out. These increases are discussed in terms of both appetite stimulating and disinhibition effects of chlordiazepoxide.
21 citations
TL;DR: The findings suggest that the majority of individuals diagnosed with a common mental disorder are not being treated with psychotropic drugs or are being inappropriately treated.
Abstract: Background: Despite increasing psychotropic drug prescriptions worldwide, little is known about utilization of these medications in the general population in Israel. We examined psychotropic drug use in the general population of Israel and the patterns of use among individuals with different DSM-IV diagnoses of 12-month mental disorders. Method: A representative sample was derived from the National Population Register of noninstitutionalized residents aged 21 and older. Face-to-face interviews were conducted from May 2003 to April 2004. Individuals were asked about any psychotropic drug use in the past 12 months. DSM-IV disorders were assessed using a revised version of the World Health Organization’s Composite International Diagnostic Interview. Results: Psychotropic drug utilization was observed in 6.9% of the general population and in 19.6% of individuals with any 12-month psychiatric disorder. The extent of use varied according to sociodemographic variables and the specific DSM-IV diagnostic categories. Among individuals with a 12-month diagnosis of pure major depression, only 13.6% received any antidepressants within the same period; exclusive use of antidepressants was 5.7%, while 3.3% of the individuals used only anxiolytics. Conclusion: Similar to findings in other European countries, our findings suggest that the majority of individuals diagnosed with a common mental disorder are not being treated with psychotropic drugs or are being inappropriately treated. (Prim Care Companion J Clin Psychiatry 2007;9:356‐363)
21 citations