Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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TL;DR: There was an increase in the severity, rather than the intensity, of mental health disorders in individuals who had already had disorders before the crisis, and the severity was accentuated in the toughest year of the economic crisis.
Abstract: Purpose
Evidence of whether the recent economic crisis has or has not had an effect on psychotropic drug consumption is very scarce. Our objective was to determine if there had in fact been an increase in psychotropic drug use as a result of the financial crisis.
Methods
In our study a retrospective cohort (between January 1, 2005, and December 31, 2012) was made up of individuals from the general population in a region in the northeast of Catalonia, Spain. We specified a generalized linear mixed model along with combined ‘selection on observables’ as (propensity scoring) matching and ‘selection on unobservables’ as (random coefficient) the panel data model methods, and performed inferences using a Bayesian framework.
Results
In the period following the economic crisis (post 2009), there was an increase in the consumption of psychotropic drugs which was significantly higher among those who had already been consuming psychotropic drugs prior to 2009 and those most likely to be unemployed. The increase was of greater significance when consumption was measured by the number of drugs being taken, rather than by the defined daily dose (DDD), with the greatest increase occurring in 2011; the very year in which Spain was most affected by the crisis.
Conclusions
Once the financial crisis had ended, there was an increase in the severity, rather than the intensity, of mental health disorders in individuals who had already had disorders before the crisis. This increase occurred in those most likely to be unemployed, and the severity was accentuated in the toughest year of the economic crisis.
21 citations
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TL;DR: This study examined the frequency and socio‐demographic and clinical correlates of ACM in Hong Kong (HK) and Beijing (BJ), China.
Abstract: Aims
To-date few studies have investigated prescription patterns of anticholinergic medication (ACM) in Chinese patients with schizophrenia in general and outpatients in particular. This study examined the frequency and socio-demographic and clinical correlates of ACM in Hong Kong (HK) and Beijing (BJ), China.
Methods
Five hundred and five clinically stable outpatients with schizophrenia were randomly selected and interviewed in HK and BJ using standardized assessment instruments. Basic socio-demographic and clinical data and psychotropic drug prescriptions were collected at the time of the diagnostic interview.
Results
ACM was found in 47.7% of (n = 241) the whole sample and in 54.1 and 41.2% of the HK and BJ samples, respectively. ACM was associated with more frequent use of antipsychotic (AP) polypharmacy, typical AP drugs, and a combination of depot and oral AP, less use of clozapine and atypical and oral AP, a lack of health insurance, higher doses of APs, severity of extrapyramidal side effects (EPS), a higher number of APs prescribed, and study sites. In multiple logistic regression analysis, higher doses of APs, less frequent use of an atypical AP, and study sites all remained significantly associated with ACM.
Conclusion
Although the ethnic and clinical characteristics of the two samples were nearly identical, there was a wide variation in the frequency of ACM prescriptions between HK and BJ suggesting that socio-cultural and economical factors as well as traditions of psychiatric practice all played a role in determining the use of ACM. Prescribing ACM in neither site was in line with current recommendation. Copyright © 2007 John Wiley & Sons, Ltd.
21 citations
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TL;DR: The psychotropic drugs most commonly used in Finnish patients with JNCL are citalopram and risperidone and the clinical outcome was good or satisfactory in 70%.The adverse effects most commonly reported were fatigue, weight gain and aggravation of extrapyramidal symptoms.
20 citations
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TL;DR: A survey in a mental hospital in Hong Kong revealed a high mean daily dose of antipsychotics and a high frequency of use of anticholinergic drugs.
Abstract: There is little information on the prescription practice for chronic schizophrenics, especially in Asia. A survey in a mental hospital in Hong Kong revealed a high mean daily dose of antipsychotics and a high frequency of use of anticholinergic drugs. The significance of these findings is discussed.
20 citations
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TL;DR: Nonpharmacological treatments such as cognitive behavioural therapy should be employed whenever possible for the treatment of anxiety disorders during pregnancy, and if medication is required pregnant women should be prescribed the lowest dosage for the minimum amount of time.
Abstract: Pregnancy is a time of great emotional change for a woman, producing increased stress and anxiety. Medication may be required for the treatment of anxiety disorders at this time. Given the fact that psychotropic drugs readily cross the placenta and could have important implications for the developing fetus, it is necessary to balance the possible effects of medication against the potential effects to both the mother and fetus if the anxiety disorder is left untreated. Despite the widespread use of psychotropic drugs such as benzodiazepines and antidepressants during pregnancy, there is a paucity of information regarding the effect of such exposure on the developing fetus. From a review of the literature it is clear that the issue of safety of psychotropic drugs during pregnancy is far from resolved. While some of the findings from animal studies are alarming, these studies cannot be directly extrapolated to humans. In addition, varying sample sizes and multiple drug exposures further complicate interpretation of human studies. Nonpharmacological treatments such as cognitive behavioural therapy should be employed whenever possible for the treatment of anxiety disorders during pregnancy. However, if medication is required pregnant women should be prescribed the lowest dosage for the minimum amount of time.
20 citations