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Psychotropic drug

About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.


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Journal ArticleDOI
TL;DR: Patients with bipolar mania have reduced P600 amplitude, comparable to patients with schizophrenia, which may represent the first neurophysiological evidence of abnormal syntactic linguistic processing in bipolarMania.

8 citations

Book ChapterDOI
01 Jan 1986
TL;DR: The major objective of this chapter is to integrate recent data concerning the molecular basis of NT-dopamine interactions into the developing concept of the functional significance of such interactions.
Abstract: The emphasis of this chapter is on the mechanisms and functional significance of the interaction of neuropeptides with the putative neurotransmitter dopamine in the central nervous system (CNS). Accumulating evidence supports the contention that these interactions are of physiological importance and have added a novel dimension to our concepts of the pathophysiology of psychiatric disorders and the mechanisms of psychotropic drug action. Primary emphasis has been placed on findings from our laboratories and those of others concerning interactions between the tridecapeptide neurotensin (NT) and dopamine neurons. Where appropriate, the influence of other neuropeptides on dopamine mechanisms are discussed. We (Nemeroff et al., 1982a, 1983a, 1984) and others (Goedert, 1984) have previously reviewed the neuropharmacological, neuroanatomical and neurochemical literature supporting a functional interaction between NT-containing and dopamine-containing cells in the CNS and the interested reader is referred to these articles for a more comprehensive review than is intended here. The major objective of this chapter is to integrate recent data concerning the molecular basis of NT-dopamine interactions into the developing concept of the functional significance of such interactions.

8 citations

Journal ArticleDOI
TL;DR: Analysis of the link between unemployment benefits and purchased prescription drugs, and to what extent the two tended to co-occur over a 6-year period, shows that on average, those who are involuntarily out of work have higher levels of psychological distress than those who have work.
Abstract: This edition of the Occupational and Environmental Medicine includes an analysis of the link between unemployment benefits and purchased prescription drugs, and to what extent the two tended to co-occur over a 6-year period.1 The authors show that an incident prescription of a psychotropic drug was twofold to threefold more likely to occur close to a period of unemployment than the same individual's risk when unemployment was not an issue. This relationship was stronger for men, more pronounced for psychotropic drugs than other classes of prescription drugs, and was at its highest 1–3 months prior to onset of unemployment. The timing coincides with the notice period in Norway, where the study was carried out. The results add to the well-established relationship between mental health and unemployment: on average, those who are involuntarily out of work have higher levels of psychological distress than those who have work. Previous systematic reviews conclude with a causal effect where becoming unemployed reduces mental …

8 citations

Journal ArticleDOI
TL;DR: Evaluated in two groups of elderly, hospitalized patients (H) vs. nonhospitalized subjects (nH), psychotropic drug consumption related to psychological distress, SCL-90 has proved to be useful for assessing the qualitative aspects of this drug consumption in the elderly.
Abstract: The use of psychotropic drugs in general has become more extended in the past 20 years. The elderly, particularly geriatric inpatients, are the group with the highest consumption. The aim of the prese

8 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202332
202268
202175
202058
201960
201876