Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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04 Sep 2014
TL;DR: The indication of discharge or pur- suit in the first interview, the number of consults and drop-outs discriminates the two populations better than in previous works.
Abstract: Objetivo: Determinar si existen diferenciasen el uso de recursos y la actividad terapeutica llevadaa cabo con las personas con y sin trastorno mentaldiagnosticable (codigos Z segun CIE-10) en los Serviciosde Salud Mental.Metodologia: Diseno: estudio descriptivo comparativo.Ambito: area sanitaria urbana. Poblacion: todoslos pacientes derivados al Centro de Salud Mental(n=1187) durante un ano. Variables: se han analizadola indicacion clinica, el numero de citas y la intervencionterapeutica a lo largo de un ano de seguimiento.Asimismo, se recogieron tambien variables sociodemograficas,clinicas y asistenciales mediante la entrevistaclinica, el test GHQ-28 y una escala de expectativas,para poder completar el estudio.Resultados: Los codigos Z son dados de alta en mayorproporcion, reciben un tercio de visitas a lo largo deun ano, faltan a mayor numero de citas y tienen unaprobabilidad casi 5 veces mayor de abandonar tras laprimera consulta que los trastornos mentales. Los pacientesdiagnosticados de trastorno mental llegan conmas tratamiento pautado desde atencion primaria, seles anade mas tratamiento, sobre todo si habian llegadosin ello a consulta, si viven solos y en el caso deser derivados via normal, que los codigos Z. A los 12meses tambien estan tomando psicofarmacos en mayorproporcion.Conclusiones: La indicacion de alta o seguimiento enla primera entrevista, el numero de citas y los abandonosdiscriminan las dos poblaciones mejor que entrabajos previos. Nuestros pacientes tienen mas medicacionpautada en el momento de la consulta, sobretodo en el caso de los codigos Z, que en los estudiosinternacionales. No obstante, la intervencion farmacologicacon los codigos Z suele ir encaminada en sumayoria a suspender los psicofarmacos. Palabras clave : Codigos Z, trastornos mentales,uso de recursos, tratamiento farmacologico. ABSTRACT: Aims: to establish the differences inthe use of resorurces and treatment with the peoplewith and without diagnosable mental (Z codes accordingto CIE 10) in a Community Mental HealthCenter.Method: Design: comparative descriptive study.Scope: urban area. Population: all patientes referredto de mental health service during a year (n=1187).Variables: clinical indication, number of consultsand therapeutic intervention throughout a year ofpursuit have been analyzed. Also, were also collectedsociodemographic, clinical and health servicesutilization variables by clinical interview, thetest GHQ-28 and a scale of expectations, in order tocomplete the study.Results: Z codes are discharged to a greater extent,receive one-third of visits over a year, missing morecitations and have a nearly 5 times more likely toleave after the first consultation that mental disorders.Patients diagnosed as mental disorder comewith more prescribed treatment from primary care,further treatment is added, especially if they comewithout it to see, if they live alone and if they are referredfor normal track than Z. codes At 12 monthsare also taking psychotropic drugs in greater proportion.Conclusions: The indication of discharge or pursuitin the first interview, the number of consultsand drop-outs discriminates the two populationsbetter than in previous works. Our patients havemore medication at the moment of the consultation,mainly in the case of the Z codes, than other studies.However, the pharmacology intervention withZ codes usually goes directed in its majority to suspendthe psychotropic drug.Key words: Z codes, mental disorder, use of resources,psychotropic drug treatment.
4 citations
01 Jan 2007
TL;DR: A marked socio-economic gradient exists with regard to MPH prescriptions, indicating an overrepresentation of privately insured patients who generally make up about 10% of all insured persons in Germany.
Abstract: Background: Attention-deficit/hyperactivity disorder (ADHD) is a chronic psychiatric disorder which most commonly affects children and adolescents. Treatment with methylphenidate (MPH) entails a dependency risk as MPH is a psychotropic drug. In Germany, according to pharmaco-epidemiological studies based on figures provided by the general health insurance scheme, MPH prescriptions have increased 40-fold over the past decade. Objective: We aimed to investigate MPH prescriptions issued by medical practitioners in the city of Cologne with a special focus on prescription practices and the proportion of MPH prescriptions issued for privately insured patients. Method: This is a descriptive study. The database consisted of all registered MPH prescriptions during the first two quarters of 2003 and included 2729 prescriptions issued by hospital and practice-based medical practitioners. Results: 23 % of all MPH prescriptions were issued on private prescriptions, indicating an overrepresentation of privately insured patients who generally make up about 10% of all insured persons in Germany. There was a high frequency of once-only prescriptions: 28% of all prescriptions fell into this category. In addition, prescribed daily doses were often lower or higher than age-specific recommended mean daily doses. Conclusion: The study provided evidence of inappropriate care patterns concerning MPH. A marked socio-economic gradient exists with regard to MPH prescriptions.
4 citations
TL;DR: Three methods for examining drug-drug interactions were compared to understand advantages and disadvantages of each: ePocrates; Interact; The Mount Sinai multiple source for the evaluation of drug- drug interactions (MS).
4 citations
TL;DR: A "therapeutical window" of blood levels between 300 to 600 ng/ml of maprotiline (oral dose of 75 or 150 mg per day) is found and there is also a relationship between clinical outcome rated by the Hamilton-Depression-Scale and the d2-cancellation-test.
Abstract: Antidepressive therapy with maprotiline was accompanied by blood level determinations psychological clinical and electroencephalographical assessments. It was the aim of the study to introduce objective methods in psychotropic drug therapy and to look for a relationship between blood level and clinical outcome, EEG and psychological data. We found a "therapeutical window" of blood levels between 300 to 600 ng/ml of maprotiline (oral dose of 75 or 150 mg per day). There is also a relationship between clinical outcome rated by the Hamilton-Depression-Scale and the d2-cancellation-test.
4 citations
TL;DR: Elevated blood leukocyte is the most important predictor for prolonged hospitalization in admitted patients with psychotropic drug overdose.
Abstract: Objective: To determine risk factors associated with their length of hospital stay in admitted patients with psy- chotropic drug overdose. Methods: Demographics, data of physical and laboratory, and hospital stay were analyzed using a linear regression and a recursive partitioning analysis to determine significant risk factors for prolonged hospitalization. Results: In 140 patients (mean age, 35 yr; 78% women) with psychotropic drug overdose, the median hospital stay was 2.9 days (range, 1-17) and all were discharged alive. Significant factors for prolonged hospital stay were older age (p<0.0001), increased heart rate (p = 0.029), lower blood pressure (p<0.0001), lower Glasgow coma scale (p = 0.015), and increased blood leukocyte (p = 0.005). The recursive partitioning showed that blood leukocyte of 12,900/mm 3 was the cutoff of the most important variable for hospital stay of 3 days or greater. Conclusions: Elevated blood leukocyte is the most important predictor for prolonged hospitalization in admitted patients with psychotropic drug overdose.
4 citations