Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: This study explores the trends in PDPs in Dutch NH residents with dementia with dementia, and investigates the combination of high threshold for NH admission and trained elderly care physicians.
Abstract: Several European studies investigated the trends in psychotropic drug prescriptions (PDPs) among nursing home (NH) residents and reported a decline in antipsychotics prescriptions. Since the Dutch long‐term care system differs from other European systems (e.g. higher threshold for NH admission and trained elderly care physicians), this study explores the trends in PDPs in Dutch NH residents with dementia.
3 citations
••
01 Jan 1991TL;DR: This chapter presents the current state of knowledge, the problems and prospects of immunological research into schizophrenia, as well as investigating the role of antibodies in the development of schizophrenia.
Abstract: This chapter presents the current state of knowledge, the problems and prospects of immunological research into schizophrenia
3 citations
••
TL;DR: In this article, the effects of single doses of oral THC on autonomic nervous system function in healthy adult women were evaluated in three laboratory sessions in which they received oral THC (7.5 and 15 mg) and placebo.
Abstract: Cannabis is the most commonly used psychotropic drug in the United States, after alcohol. Despite its apparent sedative and calming effects, cannabis and its main psychoactive constituent, ∆9 -tetrahydrocannabinol (THC) can produce serious adverse effects including tachycardia and anxiety. These effects can be especially pronounced in women, who remain underrepresented in clinical cannabinoid research. The present study is one of the first to characterize the effects of single doses of oral THC on autonomic nervous system function in healthy adult women. Occasional female cannabis users participated in three laboratory sessions in which they received oral THC (7.5 and 15 mg) and placebo. Autonomic measures included heart rate (HR), blood pressure (BP), pre-ejection period (PEP) a measure of cardiac sympathetic functioning, and high frequency heart rate variability (HF-HRV) a measure of parasympathetic cardiac control. Autonomic responses were examined in relation to subjective drug effects. THC dose-dependently increased HR, decreased HF-HRV, and increased ratings of feeling a drug effect, cannabis-like intoxication, and anxiety. Although the drug did not significantly affect BP or PEP, HR was negatively related to both PEP and HF-HRV. HF-HRV, the measure of parasympathetic activity, was significantly negatively related to subjective measures of cannabis intoxication (but not anxiety) at the 15 mg dose only. PEP was not significantly related to any subjective measure. These results extend our knowledge of the autonomic effects of THC in relation to subjective drug experience. This and future studies will help us to understand risk factors related to cannabis use.
3 citations
•
TL;DR: Pattern and frequency of substance abuse in urban population of Lucknow based upon project A study to evolve material for prevention of drug/alcohol/tobacco (substance) abuse through social marketing is presented.
Abstract: Background: The urban Lucknow community was studied during a project A study to evolve material for prevention of drug/alcohol/tobacco (substance) abuse through social marketing funded by Council of Science & Technology, Lucknow. The paper presents pattern and frequency of substance abuse in urban population of Lucknow based upon it. Method: Two mohallas of a ward from Lucknow Municipal Corporation were selected randomly. A total of 842 heads of the households (out of 5420 members) were studied using Semi Structured Socio demographic data-sheet and Proforma from WHO-ICMR a collaborative study on narcotics and psychotropic drugs. Data was analyzed using percentage, mean and S.D. Results: Out of 5420 subjects 34.31% (30.22% males & 4.09% females) were found to be substance abusers. Majority of subjects used tobacco (68.17% smoking, 65.17% eating). Conclusion : Majority of subjects were regular users constituted 73.65% tobacco smokers and 74.38% eaters/chewers, 62.38% alcoholics were experimenters and amongst those who were psychotropic drug abusers, 64.28% were dependant.
3 citations