Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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01 Jan 2013
TL;DR: An increase in the number of psychotropic medications, in particular antipsychotics, prescribed over the course of years has been noted in all psychiatric settings.
Abstract: Recent studies based on psychotropic drug use give rise to growing concern about the trend towards psychotropic and antipsychotic polypharmacy, delineating prescriptive practices contrary to treatment recommendations drawn up in international guidelines. An increase in the number of psychotropic medications, in particular antipsychotics, prescribed over the course of years has been noted in all psychiatric settings.
2 citations
Journal Article•
TL;DR: The records of 201 patients in a family medicine training clinic were examined for frequency of prescription of psychotropic drugs, and it was found that only 11.5 percent of patients received a psychotropic drug, lower than expected.
Abstract: The records of 201 patients in a family medicine training clinic were examined for frequency of prescription of psychotropic drugs. It was found that 11.5 percent (23/201 patients) had received a psychotropic drug over an average clinic visit time of 2 1/2 years. Patients were primarily female (2:1), with the socioeconomic status skewed towards the lower end, and with patient age ranging from 18 to 87 years. It was found that most psychotropic drugs were prescribed for short periods of time, with the prescriptions ranging from 1 month to 4 1/2 years. That only 11.5 percent of patients received a psychotropic drug was lower than expected. The clinic's conceptualization of the role of psychotropic drugs, the different approach utilized in data collection, or characteristics of the "training" setting, may account for these phenomena.
2 citations
01 Jan 1988
TL;DR: The decision to organize an International Collegium of Neuro-Psychopharmacology was made during the Symposium on Psychotropic Drugs, held in Milan in May 1957.
Abstract: The decision to organize an International Collegium of Neuro-Psychopharmacology was made during the Symposium on Psychotropic Drugs, held in Milan in May 1957. The Symposium was chaired by Professor Emilio Trabucchi, Director of the Istituto di Farmacologia of the University of Milan and organized by Dr. Silvio Garattini, Professor in the same institute.
2 citations
Journal Article•
TL;DR: Findings however, point to the need for discontinuing concurrent administration of lithium and benzodiazepines during ECT, as these drugs have no influence on seizure duration.
Abstract: This study examined the concurrent use of psychotropic drugs on seizure duration during Electroconvulsive therapy (ECT). Consecutive consenting patients prescribed bilateral ECT (n=182) by the treating psychiatrist were considered for the study. The concurrent psychotropic medication (antipsychotic, antidepressant, benzodiazepine and lithium) was recorded. Motor and EEG seizure durations were recorded at threshold ECT session. The seizure durations were compared between the co-administered drug and control groups for each of the psychotropic drug independently using students' t-test. Concurrent antipsychotic or antidepressant drugs had no influence on seizure duration. However, the seizure duration was longer in patients on lithium (n=30) and shorter in patients on benzodiazepines (n=67). Prolonged seizures occurred more often in the former (26.6%) but less often in the later (12%). Polypharmacy in these patients precludes firm conclusions. Findings however, point to the need for discontinuing concurrent administration of lithium and benzodiazepines during ECT.
2 citations
01 Jun 2010
TL;DR: Both clinicians and patients under-recognize the RLS and the fact that commonly prescribed medications can be the cause of RLS needs to be paid attention to.
Abstract: Restless legs syndrome (RLS) is a common sensorimotor disorder that is characterized by an urge to move the legs and peculiar, unpleasant sensations deep in the legs and its prevalence in the general population is between 3.2% and 15%. RLS significantly impairs patients' lives, often by severely disrupting sleep. However, both clinicians and patients under-recognize the RLS. RLS phenotypes include an idiopathic form and secondary form that is usually resulted from various causative conditions. The pathophysiology of RLS may be related with the dopaminergic system, which is closely linked to a number of psychotropic medications, including antidepressant and antipsychotics. Several antidepressants and antipsychotics have been shown to induce or exacerbate RLS. We need pay attention to the fact that commonly prescribed medications can be the cause of RLS.
2 citations