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Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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01 Jun 2003
TL;DR: The relationship established between the woman, the physician that and the function attributed to anxiolytic drugs by women users and medical general practitioners are examined.
Abstract: The purpose of this paper is to investigate the meaning of and the function attributed to anxiolytic drugs by women users and medical general practitioners. It examines the relationship established between the woman, the physician that
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TL;DR: An unusual reversible neurological complication of treatment with butaperazine and fluphenazine is reported in this paper.
Abstract: One of the principal side effects of neuroleptic drugs is their liability to produce a variety of neurological syndromes. Extrapyramidal symptomatology is the most frequent of these and occurs with almost all potent antipsychotic drugs and particularly with the piperazinyl phenothiazines, butyrophenones, and thioxanthenes. These side effects are usually reversible, but there have been reports that some, such as dystonia, dyskinesia, and chorea-athetosis, are sometimes irreversible (7, 12, 20). Psychotropic drugs influence many levels of the central nervous system, and their precise mode of action is still in doubt. Since any reports of unusual clinical neurological effects in man may help in determining more precisely the sites of action of these drugs, an unusual reversible neurological complication of treatment with butaperazine and fluphenazine is reported in this paper.
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TL;DR: This estudo objetivou avaliar, por meio da literatura, a forma correta de uso do metilfenidato, o uso indiscriminado, off label and os problemas de saúde that o usos prolongado pode desencadear no usuário, assim como a importância da atenção farmacêutica for um tratamento eficaz
Abstract: Methylphenidate hydrochloride [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], known as Ritalin, is a psychotropic drug commonly used by people with Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy for its treatment. As it is a drug that acts on the nervous system by releasing norepinephrine and dopamine in the synaptic clefts, causing an excitation in postsynaptic receptors and altering the user's cognitive functions, the off label use to improve cognitive performance is becoming more and more common. This type of medication must be used rationally, as well as any other medication, as they can cause adverse effects and dependence. In view of the above, this study aimed to evaluate, through the literature, the correct way to use methylphenidate, the indiscriminate use, off label and the health problems that prolonged use can trigger in the user, as well as the importance of pharmaceutical care for effective treatment with methylphenidate. For this, an integrative literature review was carried out and the articles for this review were collected in the following search portals: SciELO, BVS and Lilacs. After collection, 21 studies were selected to compose the results. It was possible to notice that the indiscriminate use of methylphenidate hydrochloride has been carried out frequently by many people, especially by students, which can lead to serious complications and the appearance of serious adverse effects, especially cardiovascular events such as tachycardia and hypertension, psychiatric disorders such as depression, psychosis and chemical dependency, as well as the neurological system such as dyskinesia, involuntary muscle contractions and spasms, among others.
2 citations
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TL;DR: The automated indicators identified frequent inappropriate drug administrations, but practices tended to become more appropriate after quality-of-care improvement actions and are structuring tools for the development of a drug prescription monitoring system.
Abstract: The appropriateness of psychotropic prescriptions in the elderly is a major quality-of-care challenge at hospital. Quality indicators have been developed to prevent inappropriate psychotropic prescriptions. We aimed to select and automatically calculate such indicators, from the Bordeaux University Hospital information system, and to analyze the appropriateness of psychotropic prescription practices, in an observational study. Experts selected indicators of the appropriateness of psychotropic prescriptions in hospitalized elderly patients, according to guidelines from the French High Authority for Health. The indicators were reformulated to focus on psychotropic administrations. The automated calculation of indicators was analyzed by comparing their measure to data collected from a clinical audit. In elderly patients hospitalized between 2014 and 2015, we then analyzed the evolution of the appropriateness of psychotropic prescription practices during hospital stay, using methods of visualization, and described practices by considering patients’ characteristics. Two indicators were automated to detect overuse and misuse of psychotropic drugs. Indicators identified frequent inappropriate drug administrations, but practices tended to become more appropriate after quality-of-care improvement actions. In the majority of patients (85%), there was no inappropriate administration of psychotropic drugs during hospital stay; for the remaining 15% with at least one inappropriate administration, physicians tended to limit overuse or misuse during hospital stay. Inappropriate administrations were more frequent in patients suffering from psychiatric disorders, dependence and associated complications or morbidities. The automated indicators are structuring tools for the development of a drug prescription monitoring system. Inappropriate psychotropic administrations were limited by physicians during hospital stay; some inappropriate prescriptions might be explained by clinical characteristics of patients.
2 citations