Psychotropic drug

About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.

Drugs and information processing in skilled performance.

Abstract: A concise review is presented of recent research on task aspects with respect to determining the effects of drugs on human information processing. It is concluded that progress in this area is hampered by lack of a theoretical basis to most behavioral tasks, preventing firm conclusions about the effects of drugs on either well-defined mental functions or on real-life performances. It is argued that the effects of drugs should only be tested in behaviorally well-researched tasks. Some proposals are discussed with an emphasis on perceptual-motor skills.

Prognostic Impact of Delirium in Older People With/Without Dementia: A Retrospective Cohort Study in Taiwan.

Abstract: To elucidate the hypothetically different interactions between delirium and post-discharge prognostic indicators in elderly hospital inpatients with versus without dementia. Retrospective cohort study of claims data by Taiwan National Health Insurance beneficiaries between 2002–2013. Records of public hospital admissions in the Taiwan National Health Insurance Research database. Propensity-score matched subgroups of patients with delirium superimposed on dementia (n = 922) versus dementia alone (n = 922), delirium alone (n = 680) versus neither delirium nor dementia (n = 680). Mortality, emergency department visits, readmissions, and psychotropic drug use, within 30, 180, and 365 days of discharge, were analyzed using multivariate proportional hazards or logistic regression analyses. Delirium superimposed on dementia was not associated with increased post-discharge mortality, or emergency department visits, but significantly increased the risk of readmissions at 365-day follow-up (adjusted HR, 95% CI: 1.26, 1.01–1.56). However, delirium without dementia was significantly associated with increased post-discharge mortality, emergency department visits and readmissions at 180 days and 365 days (respective adjusted HRs: mortality, 1.63 and 1.79; adjusted ORs: emergency department visits, 1.89 and 1.81; readmissions, 1.47 and 1.53). Delirium in patients both with dementia and without, was associated with six-fold higher likelihood of in-hospital psychotropic drug use, and doubled post-discharge psychotropic drug usage. The obvious association between in-hospital delirium and worsened long-term prognosis, irrespective of dementia, raises awareness to warrants proactive and multimodal prevention and intervention strategies. Furthermore, the mechanisms about different influence of delirium for patients with/without dementia need to be further explored.

Application of Fuzzy Similarity Index method in hypnosis analysis

Abstract: The brain is a highly complex system. Understanding the behavior and dynamics of billions of interconnected neurons from the brain signal requires knowledge of several signal-processing techniques, from the linear and non-linear domains. The analysis of EEG signals plays an important role in a wide range of applications, such as psychotropic drug research, sleep studies, seizure detection and hypnosis processing. In this paper we accomplish to analyze and explore the nature of hypnosis in right, left, back and frontal hemisphere in 3 groups of hypnotizable subjects by means of Fuzzy Similarity Index method.