Topic
Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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TL;DR: The relationship between selected resident and facility characteristics and the frequency and quality of tranquilizer prescribing and use in skilled nursing facilities is examined.
Abstract: Objective. To examine the relationship between selected resident and facility characteristics and the frequency and quality of tranquilizer prescribing and use in skilled nursing facilities.
Design. Retrospective review of medication profiles and pharmacy billing records using standardized protocol.
Settings. Seven skilled nursing facilities.
Participants. All residents aged 65 years or older were eligible. Consent was given by 760 residents or guardians. Six refused permission.
Outcome Measures. Drug use measures included the presence or absence of a tranquilizer order, any tranquilizer use during previous 30 days, and any deviation from selected drug use criteria.
Results. Of 760 residents, 38% had an order for an antipsychotic or antianxiety agent, and 28% actually received a tranquilizer. Comparing tranquilizer practices with specific drug-use criteria showed that nearly 19% of all elderly residents were exposed to some type of excess use such as long duration, polymedicine, or therapeutic duplication. Residents in facilities with less adequate staffing and other resources were significantly more likely to have a tranquilizer order, to have a tranquilizer administered, and to have any deviation from drug-use criteria. The data also show higher rates of deviation from criteria among residents with a diagnosed mental disorder, younger residents, and Medicaid recipients.
Conclusion. More attention must be paid to environmental factors that may undermine current efforts to improve psychotropic drug prescribing and use in skilled nursing facilities.
64 citations
TL;DR: 5. Barker PA, Ashcroft GW, Binns JK: Imipramine in chronic depression.
Abstract: 6 Hollister LE: Clinical Pharmacology of Psychotherapeutic Drugs New York, Churchill Livingstone, 1978 7 Shader RI, DiMascio A: Psychotropic Drug Side Effects Baltimore, Williams & Wilkins Co 1970 8 Biros D, Schiele BC, Ferguson D: A comparison of Melitracen and imipramine, in Treatment of Depressed Patients, Current Therapeutic Research, vol 2 New York, Therapeutic Research Press, 1969, pp 289-295 9 Barker PA, Ashcroft GW, Binns JK: Imipramine in chronic depression J Ment Sci 106:1447-1451, 1960
64 citations
Journal Article•
TL;DR: The syndrome of hyponatremia in psychiatric patients is described, and cases associated with psychotropic drug treatment are reviewed.
Abstract: The syndrome of hyponatremia in psychiatric patients is described, and cases associated with psychotropic drug treatment are reviewed. The causative role of the drug should be documented by rechallenge or a water loading test. In some instances it is possible to continue psychotropic treatment by restricting fluids or administering demeclocycline.
63 citations
TL;DR: Combined analyses of these markers in postmortem PCF and CSF, in addition to blood samples, are helpful for evaluating the severity of myocardial and/or skeletal muscle damage in death processes, in particular for investigating deaths due to hyperthermia, hypothermia, electrocution and intoxication.
63 citations
TL;DR: Patient-specific risk estimates provide an effective method of reducing the risk of injury for high-risk older people and reduce injury risk in older people.
63 citations