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Psychotropic drug
About: Psychotropic drug is a research topic. Over the lifetime, 2309 publications have been published within this topic receiving 54070 citations.
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TL;DR: There is no objective impairment evaluation tool available for patients on psychotropic drug therapy, health care professional, or police for psychomotor drugs other than alcohol for DUID, despite the recognition of this problem.
Abstract: Dear Editor,
Driving under the influence of drugs (DUID) is a known phenomenon that has been well explored from clinical, social, and legal viewpoints [1]. Despite the recognition of this problem, there is no objective impairment evaluation tool available for patients on psychotropic drug therapy, health care professional, or police for psychomotor drugs other than alcohol. Police in many countries sanction drivers for DUID on the basis of subjective suspicion of impairment. In a minority of countries, such as the United States and the United Kingdom, the …
01 Jan 2016
TL;DR: The results showed that physicians who were exposed to the personalized patient alerts were more likely to reduce drugs that were shown to contribute to fall risk, with greater changes occurring when greater risk was displayed.
Abstract: It is widely accepted that electronic prescribing and integrated drug information systems can reduce avoidable errors in prescribing and dispensing. An optimal system that both enhances the uptake by clinicians and improves the safety of prescribing would have features and functionality that includes the integration of patient demographic information, retrieval of all currently active drugs, automated alerts for relevant prescribing problems, integration of electronic prescriptions and drug discontinuation orders into pharmacy systems, and monitoring of patient adherence. Targeted alerts about the overuse of psychotropic drugs in the elderly would be particularly relevant since this situation represents a potentially preventable cause of injuries. This chapter describes the results of a cluster randomized trial using a cutting-edge custom-designed computer-assisted alert for the detection and management of psychotropic drug use. The results showed that physicians who were exposed to the personalized patient alerts were more likely to reduce drugs that were shown to contribute to fall risk, with greater changes occurring when greater risk was displayed. These positive findings are promising, since prescribers will do the right thing when given the information in an easily understandable format. Computerized decision support is a powerful tool to deliver value-added information to consumers and clinicians at the point of care. The next steps involve establishing the standards for delivering evidence into practice, determining what data is needed for personalized predictions, and determining how to deploy decision-support systems across multiple platforms.
01 Jan 1984
TL;DR: Research in clinical neurophysiology with respect to the technique and validity of electroencephalography revealed further possibilities for application and proved useful in special indications in anesthesiology.
Abstract: The electroencephalogram is a neurophysiological technique for examining cerebral electric activity; it can be applied to many medical fields and has allowed considerable advances to be made. This has been due to the development of data processing and signal analysis as well as to experience in the clinical application of the findings (Jung 1953; Copper etal. 1974; Dolce and Kunkel 1975; Remond 1977). Berger, whose name is linked inseparably with the history of electroencephalography, hoped to determine the mechanisms of psychic processes with this new harmless method (Kolle 1965). His expectations were not fulfilled, but he did recognize the value of electroencephalography as an experimental method in the study of drug-induced changes of consciousness. In 1933, he performed the first electroencephalogram (EEG) recording under chloroform anesthesia. Subsequently, barbiturates, synthesized in 1932, were thoroughly studied with the EEG [27]. This led to the development of EEG-controlled dosage machines [23]. Research in clinical neurophysiology with respect to the technique and validity of electroencephalography revealed further possibilities for application. In anesthesiology, the EEG has proven useful in special indications (e.g., open heart surgery, intra- and postoperative cerebral emergency).
Patent•
04 Nov 1981
TL;DR: The syn isomer of an N-benzylideneglycine derivative expressed by formula I (X and X are halogen ; R is lower alkyl) and a salt thereof was defined in this article.
Abstract: NEW MATERIAL:The syn isomer of an N-benzylideneglycine derivative expressed by formula I (X and X are halogen ; R is lower alkyl) and a salt thereof. EXAMPLE:Methyl N-[alpha-(2-amino-5-chlorophenyl)-2-chlorobenzylidene]glycinate. USE:A psychotropic drug, particularly useful as a minor tranquilizer. PROCESS:A compound of formula II (R is alkyl) is reacted with an alkali matal alkoxide, e.g. sodium methoxide or ethoxide, to give a compound of formula III, which is then hydrolyzed under acidic conditions to afford the compound of formula I.
TL;DR: The channels of heterogeneous reactions occurring during the molecule adsorption on the hot surface of the thermoemitter from refractory metal oxides have been revealed, as well as the influence of air atmosphere on these reactions.
Abstract: The results of mass spectrometric studies of surface ionization of molecules of psychotropic drugs such as chlorpromazine, amitriptyline and medazepam in an air atmosphere have been presented. The ...