Topic
Pulsatile flow
About: Pulsatile flow is a research topic. Over the lifetime, 6278 publications have been published within this topic receiving 149638 citations.
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TL;DR: Pulsatile and nonpulsatile blood flow have been intensely studied for cardiopulmonary bypass, isolated organ perfusion, and myocardial preservation and new methods to create pulsatile flow and their adaptation to the standard roller pump are discussed.
128 citations
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TL;DR: The view that each pulse of LH released from thepituitary gland is the consequence of a bolus of GnRH secreted into the pituitary portal system has been unequivocally upheld by the demonstration of synchronous increments ofGnRH assessed in the pituitsary portal circulation and of LH measured in samples of peripheral blood obtained simultaneously.
128 citations
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127 citations
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TL;DR: Doppler velocities and gradients across normal prosthetic heart valves are highly flow dependent, but the velocity ratio was independent of flow in all St. Jude, Medtronic-Hall, Starr-Edwards and Hancock valves.
127 citations
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TL;DR: It is concluded that meticulous high-volume, high-pressure pulsatile lavage reduces both pulmonary physiological derangements and fat emboli during bilateral cemented arthroplasty in dogs.
Abstract: To determine the efficacy of high-volume, high-pressure pulsatile lavage in the prevention of cardiopulmonary dysfunction and fat embolism during cemented arthroplasty, we studied twenty-eight mongrel dogs that had had a bilateral cemented arthroplasty. Significant increases in pulmonary-artery pressure and pulmonary vascular resistance, accompanied by decreases in arterial oxygen tension and increases in intrapulmonary shunt fraction (Qs/Qt), characterized cardiopulmonary dysfunction after bilateral cemented arthroplasty when no lavage was used. Low-volume, low-pressure manual lavage did not significantly alter these physiological changes, but there was a significant reduction in the number of fat emboli that were demonstrated in the lungs as compared with the no-lavage group. High-volume, high-pressure pulsatile lavage of the intramedullary cavity after reaming significantly reduced the changes in pulmonary-artery pressure, pulmonary vascular resistance, arterial oxygen tension, and intrapulmonary shunt fraction (Qs/Qt). In the pulsatile-lavage group, the number of fat microemboli that were found in the lungs was reduced to 25.7 per cent of those found in the no-lavage group. We concluded that meticulous high-volume, high-pressure pulsatile lavage reduces both pulmonary physiological derangements and fat emboli during bilateral cemented arthroplasty in dogs.
127 citations