Topic
Pulsatile flow
About: Pulsatile flow is a research topic. Over the lifetime, 6278 publications have been published within this topic receiving 149638 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: The present investigation examines the post-stenotic flow field in Plexiglas models under pulsatile conditions approximating those in the aortas of the cynomolgus monkey, an animal often employed in atherogenesis research.
75 citations
TL;DR: The present composite formulation illustrates a platform for dissecting mechanisms of in vivo regulation of effector-response properties noninvasively in the corticotropic axis of the uninfused individual.
Abstract: According to current regulatory concepts, pulsatile ACTH concentrations (CON) stimulate time-lagged cortisol secretion rates (SEC) via an implicit CON-SEC dose-response relationship. The present an...
75 citations
TL;DR: It is demonstrated that the use of an anisotropic adaptive FEM can result in an order of magnitude reduction in computing time with no loss of accuracy compared to analyses obtained with uniform meshes.
Abstract: In this study, we present an adaptive anisotropic finite element method (FEM) and demonstrate how computational efficiency can be increased when applying the method to the simulation of blood flow in the cardiovascular system. We use the SUPG formulation for the transient 3D incompressible Navier–Stokes equations which are discretised by linear finite elements for both the pressure and the velocity field. Given the pulsatile nature of the flow in blood vessels we have pursued adaptivity based on the average flow over a cardiac cycle. Error indicators are derived to define an anisotropic mesh metric field. Mesh modification algorithms are used to anisotropically adapt the mesh according to the desired size field. We demonstrate the efficiency of the method by first applying it to pulsatile flow in a straight cylindrical vessel and then to a porcine aorta with a stenosis bypassed by a graft. We demonstrate that the use of an anisotropic adaptive FEM can result in an order of magnitude reduction in computin...
75 citations
TL;DR: While an increase in the intraocular pressure on assumption of the supine position from the seated or upright position has been known for decades, the recent introduction of a means to quantify the pulsatile ocular blood flow has led to studies indicating a postural decrease in the pulses.
75 citations
TL;DR: Dynamic blood pressure was measured in 33 human finger nailfold capillaries after direct cannulation with glass micropipettes by means of a resistance servo-nulling pressure measuring method and all recordings exhibited pulsatile oscillations related to the cardiac rhythm.
Abstract: Dynamic blood pressure was measured in 33 human finger nailfold capillaries after direct cannulation with glass micropipettes by means of a resistance servo-nulling pressure measuring method. ECG, finger pulsations, and respiratory thorax excursions were monitored simultaneously. All recordings exhibited pulsatile oscillations related to the cardiac rhythm. These oscillations resembled the wave forms of arterial pulsations with steep upstroke and dicrotic notch when the pressure amplitudes were above 10 mmHg. There was no apparent dependence on respiration. In 12 instances, pressure fluctuations with frequencies ranging from 0.2 down to 0.07 Hz were observed in both the arteriolar and venular limb. Blood pressure in human skin capillaries is pulsatile and subject to remarkable fluctuations in the arteriolar as well as in the venular limb, systolic pressure values ranging from 14 to 71 mmHg and from 11 to 52 mmHg, respectively.
75 citations