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Showing papers on "Rapid eye movement sleep published in 1979"


Journal ArticleDOI
30 Nov 1979-JAMA
TL;DR: The administration of estrogens was associated with a shorter mean sleep latency, a longer period of rapid eye movement sleep, and a positive correlation between psychological intactness (as clinically ranked) and latency to sleep onset.
Abstract: A double-blind crossover study involving 16 hypogonadal women compared the effects of placebo and cunjugated estrogens, 0.625 mg daily, on gonadotropin levels, symptoms, sleep patterns, and psychological state. After one month, serum concentrations of follicle-stimulating hormone fell 31%, and levels of luteinizing hormone, 19%; the number of vasomotor flushes also decreased. The administration of estrogens was also associated with a shorter mean sleep latency, a longer period of rapid eye movement sleep, and a positive correlation between psychological intactness (as clinically ranked) and latency to sleep onset. Psychological testing, including the Clyde Mood Scale, and the Gottschalk-Gleser Test indicated that estrogens caused this group to be less outwardly aggressive but more inwardly hostile. (JAMA242:2405-2407, 1979)

195 citations


Journal ArticleDOI
TL;DR: Young and old healthy subjects with indwelling venous cannulae were found to undergo significant diurnal variations in plasma catecholamine levels, raising the possibility that this well known age effect on sleep may be related to increased sympathetic nervous system activity.
Abstract: Young and old healthy subjects with indwelling venous cannulae were found to undergo significant diurnal variations in plasma catecholamine levels Both norepinephrine and epinephrine levels peaked in late morning and reached lowest values at night during sleep Catecholamine levels were similar during slow wave and rapid eye movement sleep While epinephrine levels were unaffected by age, norepinephrine levels were greater in older subjects by 28‰ during the day (at 1100 h; P < 001) and by 75‰ at night (between 2200-0900 h; P < 001) Older subjects slept less well; they had 90‰ less stage 4 sleep, 27‰ less rapid eye movement sleep, and twice as much wakefulness at night (P < 005) These findings raise the possibility that this well known age effect on sleep may be related to increased sympathetic nervous system activity

185 citations


Journal ArticleDOI
Peter Ramm1
TL;DR: A critical reexamination of the literature suggests that it is improbable that REM is essential to or an important factor in the maintenance of CA homeostasis, or that catecholaminergic neurons of the LC region are “REM-executive", or that CA neurons mediate REM occurrence.

79 citations


Journal Article
TL;DR: A case of narcolepsy with marked cataplexy and clomipramine hydrochloride treatment resulted in episodes of severe motor hyperactivity during sleep, which were most intense during rapid eye movement sleep.
Abstract: A case of narcolepsy with marked cataplexy is described in detail. Clomipramine hydrochloride effectively controlled the cataplexy and partially alleviated the daytime sleep attacks. However, clomipramine treatment resulted in episodes of severe motor hyperactivity during sleep, which were most intense during rapid eye movement sleep.

41 citations


Journal ArticleDOI
01 Jan 1979-Sleep
TL;DR: The actioculographic monitor (AOGM) is a newly developed, flexible system for sleep recording using three criteria: eye movements, body movements, and submental electromyogram.
Abstract: The actioculographic monitor (AOGM) is a newly developed, flexible system for sleep recording using three criteria: eye movements, body movements, and submental electromyogram. The signals are recorded on a four-channel Medilog casette tape and displayed by a mingograph at very low speed. The record is then scored after certain criteria for stages wake, nonrapid eye movement, and rapid eye movement sleep. High statistical correlations were obtained when scoring of the AOGM was compared to scoring of standard polygraphic sleep recordings.

30 citations


Journal ArticleDOI
TL;DR: It is indicated more precisely that typical impairments associated with the deprivation procedures may be due to isolated periods of non-REM sleep, rather than due to the simple absence of rapid eye movement sleep.

19 citations


Journal ArticleDOI
TL;DR: A lower than normal percentage of rapid‐eye‐movement (REM) sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity.
Abstract: The electrophysiological features of 3 brothers with the classic form of Pelizaeus-Merzbacher disease (PMD) were studied. Two consecutive overnight polygraphic sleep recordings indicated a gross distortion of rapid-eye-movement (REM) sleep for all patients. A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity. Non-rapid-eye-movement (NREM) sleep, in contrast to reported findings in 1 patient with PMD, was uniformly characterized by distinct stages in which the electroencephalograms contained frequent vertex waves and spindles. Tests of peripheral nerve conduction velocity, acoustic brainstem reflexes, and visual and auditory evoked potentials did not indicate any abnormalities, nor did electroencephalograms obtained during wakefulness. One patient did have epileptifrom spikes and spike waves recorded during an all-night EEG, an unusual finding in a child with cerebral white matter disease.

12 citations