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Rapid eye movement sleep

About: Rapid eye movement sleep is a research topic. Over the lifetime, 3740 publications have been published within this topic receiving 183415 citations. The topic is also known as: REM sleep & REMS.


Papers
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Journal ArticleDOI
01 Mar 1997-Sleep
TL;DR: It was concluded that early morning work causes a reduction of sleep time and an increase in apprehension stress.
Abstract: The aim of the present study is to investigate how early morning work affects sleep and alertness. Twenty-two females, employed as airline cabin crew members, participated in the study. The design included two sleep conditions (work day and free day) for an early group and for a control group. The results show that early morning work reduced sleep to 5 hours and 12 minutes and that the reduction of sleep consisted of less stage 2 and rapid eye movement (REM) sleep. However, when the analysis was restricted to the first 5 hours, no differences in sleep stages, arousals, or sleep continuity were obtained between groups or conditions. Analysis of electroencephalogram (EEG) power density for the 0.5-16.5 Hz bands across nonREM periods showed no differences. With respect to the subjective ratings, early morning work was associated with more apprehension of difficulties in awakening and insufficient sleep. Daytime alertness and ease of awakening did not differ between groups, but the early group had significantly more sleepiness and complained more of unrefreshing sleep in connection with the work day compared to the free day. Ratings of insufficient sleep and high daytime sleepiness were mainly predicted (multiple regression analyses) by short total sleep time (TST), whereas apprehension of an unpleasant awakening was predicted by an early wake-up time. It was concluded that early morning work causes a reduction of sleep time and an increase in apprehension stress.

117 citations

Journal ArticleDOI
TL;DR: It is proposed that the convergent evolution of homeostatically regulated SWS in mammals and birds was directly linked to the convergence evolution of large, heavily interconnected brains capable of performing complex cognitive processes in each group.

117 citations

Journal ArticleDOI
TL;DR: A better understanding of the effect of postoperative sleep disruptions on pain perception would help in selecting patients at risk for more severe pain and may facilitate the development of more effective and safer pain management programs.

116 citations

Journal ArticleDOI
TL;DR: Orexins excite TM neurons directly and by disinhibition, gated by dynorphin, which might explain some of the neuropathology of narcolepsy.
Abstract: High activity of the histaminergic neurons in the tuberomammillary (TM) nucleus increases wakefulness, and their firing rate is highest during waking and lowest during rapid eye movement sleep. The TM neurons receive a prominent innervation from sleep-active gamma-aminobutyric acidergic (GABAergic) neurons in the ventrolateral preoptic nucleus, which inhibits them during sleep. They also receive an excitatory input from the orexin- and dynorphin-containing neurons in the lateral hypothalamus, which are critically involved in sleep regulation and whose dysfunction causes narcolepsy. We have used intracellular recordings and immunohistochemistry to study if orexin neurons exert control over the GABAergic inputs to TM neurons in rat hypothalamic slices. Dynorphin suppressed GABAergic inputs and thus disinhibits the TM neurons, acting in concert with orexin to increase the excitability of these neurons. In contrast, both orexin-A and orexin-B markedly increased the frequency of GABAergic potentials, while co-application of orexin and dynorphin produced responses similar to dynorphin alone. Thus, orexins excite TM neurons directly and by disinhibition, gated by dynorphin. These data might explain some of the neuropathology of narcolepsy.

116 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202353
2022115
2021116
2020107
201995
201883