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Showing papers on "Reference Daily Intake published in 1994"


Journal Article
TL;DR: Nutrient reference data from the third National Health and Nutrition Examination Survey provide essential information to achieve intervention strategies aimed at reducing the prevalence of nutrition-related diseases and designing nutrition policies and nutrition education and assistance programs.
Abstract: Intervention strategies aimed at reducing the prevalence of nutrition-related diseases, including designing nutrition policies and nutrition education and assistance programs, require effective monitoring of what Americans are eating. Nutrient reference data from the third National Health and Nutrition Examination Survey provide essential information to achieve these goals. Mean and median iron intakes were adequate in males of all race-ethnic groups but were generally low in females and young children. Mean and median calcium intakes were also higher in males than in females and were lower than recommendations in adolescents and in women of all ages. Mean sodium intakes for all age, sex, and race-ethnic groups exceeded the minimum requirements of healthy persons and were higher in non-Hispanic black children and adolescents than in non-Hispanic white and Mexican American children and adolescents. Mean fiber intakes also did not meet recommendations in most subgroups and were higher in Mexican American adults followed by non-Hispanic white adults and non-Hispanic black adults. Further research is planned to compare the food sources of energy and nutrients consumed by different population groups in NHANES III to similar results from earlier nation surveys. NHANES III, Phase 2 (1991-94) recalls were collected using the same dietary method as those collected in Phase 1 (1988-91), and other analyses will compare findings from both phases of NHANES III.

439 citations


Journal ArticleDOI
TL;DR: The demographic and life-style characteristics that place older individuals at high nutritional risk need to be considered, particularly advanced age, gender, living situation, smoking, dietary behavior, educational attainment and dental health.
Abstract: Background To better define nutritional risk among older Americans, a cross-sectional study of nutrition and health status was carried out in a probability sample of 1,156 free-living elders, 70 years and older, from 67 communities representing urban and rural areas of the six New England states. Method All participants completed telephone interviews concerning demographic and health characteristics. A subsample of 1,156 individuals underwent in-home assessments of oral health, anthropometrics, and nutritional risk, including a 24-hour dietary recall. Results Nutrition-related problems were common and diverse among New England elders. Some 41.5% were overweight (BMI > 27 kg/m2), and mean dietary lipid intakes were considerably above recommended levels (Healthy People 2000 (National Health Promotion and Disease Prevention Objectives). Some 16% were underweight (BMI 75% the Recommended Dietary Allowance for persons 51 years and older) for three or more key nutrients. Persons of advanced age or who smoked were more likely to have high dietary lipid intakes or less than adequate nutrient intake. Higher dietary lipid levels were also more common among men and individuals who lived with others. Low nutrient intake was more prevalent in those with lower educational attainment and dental problems. Conclusion Nutrition policies and multidisciplinary interventions for older Americans need to emphasize the spectrum of nutritional problems in the elderly, including dietary excesses and potential nutrient deficiencies. The demographic and life-style characteristics that place older individuals at high nutritional risk need to be considered, particularly advanced age, gender, living situation, smoking, dietary behavior, educational attainment, and dental health.

126 citations


Journal Article
TL;DR: In Linxian China, the esophageal/gastric cardia cancer mortality rates are among the highest in the world as discussed by the authors, and there is suspicion that chronic deficiencies of multiple micronutrients are etiologically involved.
Abstract: In Linxian China, the esophageal/gastric cardia cancer mortality rates are among the highest in the world. There is suspicion that the population9s chronic deficiencies of multiple micronutrients are etiologically involved. We conducted two randomized, placebo-controlled nutrition intervention trials to test the effects of vitamin and mineral supplements in lowering the rates of esophageal/gastric cancer. In the first trial, the dysplasia trial, 3318 adults with a cytological diagnosis of esophageal dysplasia received daily supplementation with 26 vitamins and minerals in doses typically 2–3 times the United States Recommended Daily Allowances, or placebos, for 6 years. The second trial, the general population trial, involved 29,584 adults and used a one-half replicate of a 2 4 factorial experimental design which tested the effects of four combinations of nutrients: A, retinol and zinc; B, riboflavin and niacin; C, vitamin C and molybdenum; and D, β-carotene, vitamin E, and selenium. Doses for these daily supplements ranged from 1 to 2 times the United States Recommended Daily Allowances, and the different vitamin/mineral combinations or placebos were taken for a period of 5.25 years. As part of the general population trial, and end-of-intervention endoscopy survey was carried out in a small (1.3%) sample of subjects to see if supplementation affected the prevalence of dysplasia and early cancer. Herein we review the methods of these trials and the results of the endoscopic survey. Fifteen esophageal and 16 gastric cancers were identified in endoscopic biopsies from the 391 subjects evaluated from two villages, and nearly all were asymptomatic. No significant reductions in the prevalence of esophageal or gastric dysplasia or cancer were seen with any of the four supplement groups. However, the prevalence of gastric cancer among participants receiving retinol and zinc was 62% lower than those not receiving those supplements ( P = 0.09), while participants receiving β-carotene, vitamin E, and selenium had a 42% reduction in esophageal cancer prevalence (0.34). We have reported separately that cancer mortality over the entire 5.25-year period was significantly reduced among those receiving β-carotene, vitamin E, and selenium. The findings from the overall trial and the endoscopic sample offer a hopeful sign and should encourage additional studies with these agents in larger numbers of subjects.

114 citations


Journal Article
TL;DR: Cancer mortality over the entire 5.25-year period was significantly reduced among those receiving beta-carotene, vitamin E, and selenium and should encourage additional studies with these agents in larger numbers of subjects.
Abstract: In Linxian China, the esophageal/gastric cardia cancer mortality rates are among the highest in the world. There is suspicion that the population's chronic deficiencies of multiple micronutrients are etiologically involved. We conducted two randomized, placebo-controlled nutrition intervention trials to test the effects of vitamin and mineral supplements in lowering the rates of esophageal/gastric cancer. In the first trial, the dysplasia trial, 3318 adults with a cytological diagnosis of esophageal dysplasia received daily supplementation with 26 vitamins and minerals in doses typically 2-3 times the United States Recommended Daily Allowances, or placebos, for 6 years. The second trial, the general population trial, involved 29,584 adults and used a one-half replicate of a 2(4) factorial experimental design which tested the effects of four combinations of nutrients: A, retinol and zinc; B, riboflavin and niacin; C, vitamin C and molybdenum; and D, beta-carotene, vitamin E, and selenium. Doses for these daily supplements ranged from 1 to 2 times the United States Recommended Daily Allowances, and the different vitamin/mineral combinations or placebos were taken for a period of 5.25 years. As part of the general population trial, and end-of-intervention endoscopy survey was carried out in a small (1.3%) sample of subjects to see if supplementation affected the prevalence of dysplasia and early cancer. Herein we review the methods of these trials and the results of the endoscopic survey. Fifteen esophageal and 16 gastric cancers were identified in endoscopic biopsies from the 391 subjects evaluated from two villages, and nearly all were asymptomatic. No significant reductions in the prevalence of esophageal or gastric dysplasia or cancer were seen with any of the four supplement groups. However, the prevalence of gastric cancer among participants receiving retinol and zinc was 62% lower than those not receiving those supplements (P = 0.09), while participants receiving beta-carotene, vitamin E, and selenium had a 42% reduction in esophageal cancer prevalence (0.34). We have reported separately that cancer mortality over the entire 5.25-year period was significantly reduced among those receiving beta-carotene, vitamin E, and selenium. The findings from the overall trial and the endoscopic sample offer a hopeful sign and should encourage additional studies with these agents in larger numbers of subjects.

98 citations


Journal ArticleDOI
TL;DR: The results suggest that nutritional factors are relevant to bone health in postmenopausal women, and dietary supplementation may be indicated for the prophylaxis of osteoporosis.
Abstract: Qualitative and quantitative differences in the dietary habits of postmenopausal women were studied to assess their influence on bone health and osteoporosis. A total of 194 postmenopausal women were studied with forearm DEXA densitometry. 70 were osteoporotic and 124 served as controls. Women had been menopausal for 5-7 years, and had never been treated with hormone replacement or drug therapy. A 3-day dietary recall was completed on Sunday, Monday and Tuesday after the examination: the results were processed by computer and daily calcium, phosphorus and magnesium intakes were related to bone mineral content (BMC). Data were compared with Student's t-test and significance was assessed at p < 0.05. Regression analysis was performed to correlate BMC and intake levels. The dietary intake of calcium, phosphorus and magnesium was significantly reduced in osteoporotic women and correlated with BMC. Calcium and magnesium intakes were lower than the recommended daily allowance even in normal women. The results suggest that nutritional factors are relevant to bone health in postmenopausal women, and dietary supplementation may be indicated for the prophylaxis of osteoporosis. Adequate nutritional recommendations and supplements should be given before the menopause, and dietary evaluation should be mandatory in treating postmenopausal osteoporosis.

81 citations


Journal ArticleDOI
TL;DR: There is no reason to believe that elderly people are more conservative regarding their food choices than the rest of the population--at least not at the relatively young ages studied, and both cohort and longitudinal age changes in dietary habits are revealed.
Abstract: The aim of the investigation was to study cohort differences at age 70 in probands born in 1901/02 and 1911/12 and to study longitudinal changes of dietary habits and intake of energy and nutrients between ages 70 and 76. The study is part of the gerontological and geriatric population studies in Gothenburg, Sweden. The intake of both energy and nutrients was higher in the later cohort. One explanation for this lay in the choice of food items in that cohort. Intake of energy and almost all nutrients decreased in both men and women between ages 70 and 76. Energy intake reduced by 23% in men and 20% in women. The proportion of probands with nutrient intakes below RDA increased significantly at age 76. The study revealed both cohort and longitudinal age changes in dietary habits. There is no reason to believe that elderly people are more conservative regarding their food choices than the rest of the population--at least not at the relatively young ages studied.

68 citations


01 Jun 1994
TL;DR: In this article, the authors used the store-turnover method to measure the apparent dietary intake in six remote Australian Aboriginal communities using the "store-turnoff" method. The method is based on the analysis of community-store food invoices.
Abstract: Apparent per capita food and nutrient intake in six remote Australian Aboriginal communities using the ‘store-turnover’ method is described. The method is based on the analysis of community-store food invoices. The face validity of the method supports the notion that, under the unique circumstances of remote Aboriginal communities, the turnover of foodstuffs from the community store is a useful measure of apparent dietary intake for the community as a whole. In all Aboriginal communities studied, the apparent intake of energy, sugars and fat was excessive, while the apparent intake of dietary fibre and several nutrients, including folic acid, was low. White sugar, flour, bread and meat provided in excess of 50 per cent of the apparent total energy intake. Of the apparent high fat intake, fatty meats contributed nearly 40 per cent in northern coastal communities and over 60 per cent in central desert communities. Sixty per cent of the apparent high intake of sugars was derived from sugar per se in both regions. Compared with national Australian apparent consumption data, intakes of sugar, white flour and sweetened carbonated beverages were much higher in Aboriginal communities, and intakes of wholemeal bread, fruit and vegetables were much lower. Results of the store-turnover method have important implications for community-based nutrition intervention programs.

68 citations


Journal ArticleDOI
TL;DR: Analysis of data from the NHANES II survey of 1976-80 suggests that consumption of foods from the "other" group displaced nutrient-dense Foods from the diets of NHANes II respondents.
Abstract: To examine the association of consumption of foods from the fats, sweets, and the alcohol group (”other group) with nutrient profiles.Using data from the NHANES II survey of 1976-80, we categorized the foods reported to be consumed by adults (n = 11,528) into six groups: meat, dairy, grain, fruit, vegetable, and “other.”Nearly one-third of total daily energy intake was contributed by foods from the “other” category. As the proportion of daily energy intake from “other” foods increased, total daily energy intake also increased, as did the percent energy from carbohydrate and alcohol. However, percent energy from fat and protein, intake of all examined micronutrients (except vitamin E), nutrient density, and the proportion of the population meeting the RDA of various nutrients declined with increasing intake of “other” foods. Respondents were more likely to report no servings as well as less than the recommended servings of foods from the major food groups with increasing intake of “other” foods.The data su...

53 citations


Journal ArticleDOI
TL;DR: The combined dietary/supplemental water-soluble vitamin intake of the patients exceeded the recommended daily allowance in all but one patient, and serum vitamin A levels were elevated despite the lack of supplementation.
Abstract: The oral vitamin intakes and blood vitamin concentrations of seven infants receiving long-term peritoneal dialysis were measured. The serum concentrations of vitamin A, vitamin B12, vitamin C and folic acid were determined. Thiamine and riboflavin were assessed by the activation of erythrocyte transketolase and erythrocyte glutathione reductase, respectively. Vitamin B6 was measured as plasma pyridoxal phosphate. All patients received a daily vitamin supplement devoid of vitamin A. Dietary vitamin intake was derived from infant formula. In all cases, the patients' blood concentrations of the water-soluble vitamins were equal to or greater than normal infant values. Serum vitamin A levels were elevated despite the lack of supplementation. The combined dietary/supplemental water-soluble vitamin intake of the patients exceeded the recommended daily allowance in all but one patient. These preliminary data emphasize the need to further evaluate the vitamin requirements of infants receiving long-term peritoneal dialysis.

39 citations


Journal Article
TL;DR: Evidence of growth retardation and wasting in this population, coexisting with emergent obesity, is revealed, and the development of a nutrition and health policy to address the problems of both deficit and excess represents a pressing challenge.
Abstract: During the first quarter of 1990 Xhosa-speaking nurses interviewed mothers and took anthropometric measurements of 163 children 3-6 years old living in squatter and formal housing areas of Cape Town South Africa to determine the nutritional status of the children. 39% of the children received less than 67% of the recommended daily allowance (RDA) of calories (i.e. deficiency) and 3% received more than 120% of the RDA. Most children were deficient in calcium (80%) iron (77%) vitamin A (64%) riboflavin (52%) niacin (53%) vitamin B6 (58%) and vitamin C (76%). Most children received more than 120% of the RDA for folic acid (68%) and for vitamin B12 (63%). Milk consumption was low (median intake 0.5 portion vs. 2-3 portions as recommended by the department of national health and population development guidelines). The diet was also deficient in vegetables and fruit intake (1.32 vs. =or> 4 portions) and fat intake (2.5 vs. =or> 4 portions). Children did receive adequate portions of meat and foods from the cereal group however. Macronutrient energy distribution fell within prudent dietary guidelines: 28.1% of energy from total fat 63.7% from carbohydrates and 13.2% from protein. 44.8% of children had only 2 meals with more than 600 kJ. 15 children (9.2%) had only 1 meal. 27.6% were stunted. 7.7% were underweight. 7.9% were wasted. 20.1% were obese. The undernourished children and the obese children consumed a diet low in micronutrients. These anthropometric findings indicate a population in transition--acutely and chronically undernourished children coexisting with obesity. The overall findings suggest a need to develop a nutrition and health policy to address nutrient deficit and excess.

31 citations


Journal ArticleDOI
TL;DR: This analysis uses the 1989 to 1990 and 1990 to 1991 Continuing Survey of Food Intake by Individuals and companion Diet and Health Knowledge Surveys to show that health information regarding dietary fat intake has a significant impact on meal planner food choices.
Abstract: An endogenous switching regression model is used to estimate the effect that health information has on the food purchase decisions of meal planners. Specifically, we examine how information concerning the health implications of dietary fat intake influences the meal planner's daily intake of total and saturated fat. This analysis uses the 1989 to 1990 and 1990 to 1991 Continuing Survey of Food Intake by Individuals (CSFII), and companion Diet and Health Knowledge Surveys (DHKS). Our results show that health information regarding dietary fat intake has a significant impact on meal planner food choices.

Journal ArticleDOI
TL;DR: The questionnaire did not provide an accurate assessment of measured intake and could not replace the dietary recall, and there were significant differences in recalled intake for energy and percent of calories from saturated fat.
Abstract: To select a valid method for obtaining dietary intake of preschool children, food intake of 17 children (8 in daycare programs and 9 in home care) was measured for three days. Each day, home caregivers and daycare staff were asked to recall what the child had eaten during the previous 24 hours. After the third day, the Willett Food Frequency Questionnaire was administered to assess intake during the preceding seven days, which included the three days of measured foods. There were no significant differences between means from measured and recalled intake. Although the children's gender and care status (daycare versus home care) made no difference in measured intake, there were significant differences in recalled intake for energy and percent of calories from saturated fat. In this study the questionnaire did not provide an accurate assessment of measured intake and could not replace the dietary recall.

Journal ArticleDOI
TL;DR: Considering variation existed in the dietary intake of both males and females with some individuals in both groups consuming a diet containing less than the RDA in one or more nutrients due to a decrease in food intake.
Abstract: This study was conducted to assess the dietary intake of individuals experiencing a current episode of major depression.Twenty-two females and 7 males experiencing moderate to severe depression completed 3-day food records. These food records were analyzed to obtain an estimate of the nutrient intake of male and female individuals experiencing a depressive episode and this nutrient intake was compared to the Recommended Dietary Allowances (RDA).Females, as a group, consumed a diet that provided 100% of the RDA whereas the diet of males was deficient in energy and 4 of 16 nutrients examined. Considerable variation existed in the dietary intake of both males and females with some individuals in both groups consuming a diet containing less than the RDA in one or more nutrients due to a decrease in food intake.A substantial percentage of the depressed sample consumed less than the RDA of one or more nutrients. This seems to be due to an inadequate food intake rather than a deficient diet.

Journal ArticleDOI
TL;DR: This study shows that most of the dietary nutrient's intake is related to socio-economic and physical factors, and subjects with a lower dietary intake of those nutrients had a higher risk of death.
Abstract: Many observations agree on the existence, in older ages, of nutritional deficiencies secondary to dietary intake. This study investigated to what extent dietary intake of calories, protein, iron and vitamins influences the 6-year mortality in an elderly population living at home. To prevent the confounding effect of non-dietary factors, such as gender, functional and health status, socio-economic conditions and health risk habits, these variable have also been considered. The dietary intake was calculated comparing the content of nutrients in self-reported, 24-hour diet, with the 1980 Recommended Dietary Allowances (RDA) obtaining a percentage for each nutrient. The percentage difference from the RDA was tested on 6-year mortality using a bivariate regression model. The intake of protein, vitamin A, thiamin, niacin, vitamin B6 and folate was significantly related to mortality: subjects with a lower dietary intake of those nutrients had a higher risk of death. When nutrient intake was tested in a multiple regression model, adjusted for non-dietary potential confounders, only folate was an independent predictor of mortality. This study shows that most of the dietary nutrient's intake is related to socio-economic and physical factors.

Journal Article
TL;DR: The dietary intake of calcium in postmenopausal Chinese women is below the recommended daily allowance for adult females in East Asia, and coupled with other factors may predispose to the development of osteoporotic fractures.
Abstract: Dietary calcium intake has been shown to vary both between and within populations. The aim of this study was to compare two methods of assessment of dietary calcium in the local population of postmenopausal Chinese women. The intake was measured using 24h dietary recall as well as a food frequency questionnaire. There was a high correlation in the measurement of calcium intake between these methods. The mean daily intake in postmenopausal women not taking calcium supplementation was 397.6 mg assessed using 24 h recall, and 390.9 mg according to the food frequency questionnaire. There was no evidence of a difference in the reproducibility of the results given by the two methods. The dietary intake of calcium in postmenopausal Chinese women is below the recommended daily allowance for adult females in East Asia, and coupled with other factors may predispose to the development of osteoporotic fractures.


Journal Article
TL;DR: The nutritional status of women in developing countries worsens following early marriage through repeated pregnancies interspersed with prolonged lactation and until menopause and could be improved through nutrition education and supplemental nutrition for pregnant and lactating women.
Abstract: Dietary intake in pregnant, lactating and non-pregnant nonlactating women of an urban slum in Kurnool, A.P. are about 30% less than the ICMR recommended daily allowances. Heights and weights of the subjects are similar to the National Nutrition Monitoring Bureau's values for slum women and some inter-religious difference is observed in the anthropometry of the subjects.

Journal ArticleDOI
TL;DR: The results show considerable evidence of a number of major nutrients in which there were low intakes, and a nutrient score was developed where points are awarded based on the number of nutrients falling below the Lower Reference Nutrient Intake, the Estimated average Requirement or below half the daily Estimated Average Requirement.
Abstract: Two hundred and thirty-five tenants living in sheltered housing in Scotland were surveyed to identify the extent of under-nutrition and the social factors which contribute to its development. A validated 24 h recall and the nutrient checklist published by NAGE were used to evaluate patterns of dietary intake. A questionnaire was developed which included scales designed to measure depression, social engagement, cognitive function, mobility and functional ability. The results show considerable evidence of a number of major nutrients in which there were low intakes. In order to express the extent of poor nutrition, a nutrient score was developed where points are awarded based on the number of nutrients falling below the Lower Reference Nutrient Intake, the Estimated Average Requirement or below half the daily Estimated Average Requirement.

Journal ArticleDOI
TL;DR: Findings indicate the need for further health education concerning the importance of dietary calcium in young women and many young women on self-imposed energy reduction diets are at risk of a dietary calcium intake deficit at a time when it should be enhanced.
Abstract: Average dietary calcium intake and energy intake of 113 18-year-old university students in Western Australia was examined. Four-day, weighted diet records, including 1 weekend day, were completed by the subjects. A large proportion of the students (68%) had an average daily calcium consumption below the 800 mg recommended by the National Health and Medical Research Council of Australia. A strong positive association was also found between dietary calcium and dietary energy intakes. Many young women on self-imposed energy reduction diets are at risk of a dietary calcium intake deficit at a time when it should be enhanced. These findings are significant for nursing practice as they indicate the need for further health education concerning the importance of dietary calcium in young women.


Journal Article
J F Hu1, X H Zhao, B Parpia, J S Chen, T C Campbell 
TL;DR: The results indicate that the modified household method is appropriate for assessing food intakes of individuals in large nutritional studies.
Abstract: OBJECTIVE: A 'modified' household dietary method to estimate individual intakes from total household intakes was evaluated in comparison to the individual food weighing method, i.e. direct weighing of foods consumed by individuals. DESIGN: Foods consumed by the household were weighed and recorded over a 3 day period and were proportionally allocated to a specific person in the household by using energy conversion factors based on age, gender and physical activity. The individual dietary intakes were standardized by body weight (ratio of individual body weight to reference body weight from Chinese Recommended Daily Allowances (Acta Nutr. Sin. 12, 1-9), and were compared with the estimates from the individual food weighing method for both accuracy and associations with bone density. SETTING: The subjects were randomly selected from five rural countries in China, characterized by different dietary patterns. SUBJECTS: A total of 712 women aged 35-75 years participated in the dietary and bone measurements. RESULTS: Nutrient intakes estimated by the modified household method (adjusting for body weight were very similar to those obtained by the individual method (r = 0.53-0.78, P < 0.001), except for sodium which had the largest deviation from the individual methods (r = 0.23, P < 0.001). Calcium intakes were 405 +/- 271 and 409 +/- 323 mg/day, respectively, as estimated by the individual and modified household methods. A very similar degree of correlation with radial bone density also was obtained for both calcium estimates. CONCLUSION: The results indicate that the modified household method is appropriate for assessing food intakes of individuals in large nutritional studies.

Journal ArticleDOI
TL;DR: In general, the women in the study reported healthier diets than did women in a general national survey of nutrient intake conducted in 1985, and 5 amenorrheic women reported a significantly lower nutrient density intake of fat and higher intake of carbohydrate, fiber, and vitamin A than did the nonamenorrheics.
Abstract: The nutrient intakes of women who ran at different levels of intensity and the relationship between nutrient intake and ovulatory disturbances were studied. Ninety‐five women, including sedentary non‐runners (N = 16), low‐level runners (n = 27), medium‐level runners (n = 29), and high‐level runners (n = 23), completed data for a 3‐day nutritional assessment. The high‐level runners met the Food and Nutrition Board's Recommended Daily Allowances (RDAs) for all 17 nutrients examined, with the exception of calcium. The other groups of women failed to meet RDAs for iron, carbohydrate, and fiber. In general, the women in the study reported healthier diets than did women in a general national survey of nutrient intake conducted in 1985. Eighty‐two of the women reported luteinizing hormone level data that were accurate enough to indicate ovulatory functioning; of these women, 30 had ovulatory disturbances. There was no relationship between ovulatory disturbance and nutrient intake; however, 5 amenorrheic women re...

Journal Article
TL;DR: A diet poor in energy, calories, fats, and those micronutrients that have come under study, and that is unbalanced because of a relative excess of sugars, with its resulting effect on body weight, is strongly associated with and causally related to epidemic neuropathy.
Abstract: The epidemic of neuropathy that arose in Cuba in late 1991 has clinical manifestations similar to those of other neuropathies that are nutritional in origin. In an effort to identify its possible association with the diet, a case-control study was conducted at the beginning of the epidemic in Isla de la Juventud. Dietary intake was assessed through a semi-quantitative survey of consumption frequency obtained by direct personal interviews, and measurements were taken of the weight, height and skin fold thickness of 34 cases and 65 controls. As compared to controls, cases showed more pronounced weight loss prior to becoming ill, a lower body mass index (BMI), a lower percentage of body fat, and a poorer diet. According to odds ratios (OR) resulting from the separate analysis of each variable, factors associated with illness were weight loss, low BMI, low weight for height, a lower consumption of bread and rice, a less balanced diet, lack of milk intake, an intake of sugar greater than 15% of total energy consumed, consumption of alcohol, and smoking. The association was protective in the case of beans, tubercles, starchy roots, oil, and meat substitutes made from soy. Multifactorial analysis revealed higher OR values, adjusted for smoking and alcohol consumption, for intakes of less than 50% of the recommended daily allowance of protein, pyridoxine, thiamine, energy, vitamin E, niacin, folic acid, fat, riboflavin, and vitamin A. The results of this analysis show that tobacco and alcohol promote the effects of a deficient diet, but do not in and of themselves explain the association. A global analysis of these results leads to the conclusion that a diet poor in energy, calories, fats, and those micronutrients that have come under study, and that is unbalanced because of a relative excess of sugars, with its resulting effect on body weight, is strongly associated with and causally related to epidemic neuropathy.


Journal ArticleDOI
TL;DR: A revised estimation method for the daily intake of food contaminants and additives is proposed, based on food consumption data of 159 female volunteers, without using the National Nutrition Survey data, which succeeded in making clear the intakes of food additives and contaminants.
Abstract: Recommended Dietary Allowances (RDAs) are allocated to each food article as published in the Denmark Budget Methods in the Codex Alimentalius of the WHO/FAO Joint Committee when standards of pollutants in food are needed. When daily intakes of Food Additives and Contaminants need to be calculated, the Theoretical Maximum Daily Intake (TMDI) and the Estimated Maximum Daily Intake (EMDI) have been generally used. TMDI and EMDI are calculated using the formulae shown below;TMDI=n∑i=1AiXi, EMDI=n∑i=1liAiXii: food article(i=1, …, n)A: standard value for food additives and contaminantsX: mean weight of food article consumed dailyl: rate of residue after cookingExposure assessment should be more exact in order to meet social health needs and to help avoid unnecessarily strict regulations. The U. S. Food and Drug Administration (FDA) is continually improving its estimates of the dietary intakes of pesticides and essential minerals, and comparing these intakes with established safe or recommended dietary intake levels. Dietary survey methods have also improved in parallel, with examples being the USDA's Household Food Consumption Survey (1955 and 1965) and National Health and Nutrition Examination Survey II (1976-1980).In Japan, TMDI and EMDI have received more attention as methods of estimating the daily intakes of food additives and contaminants than has the Total Diet Study, even though the former are not as exact as the latter.The Japanese National Nutrition Survey is one of the most respected nutrition surveys in the world, because it has continued nationwide yearly since 1946. Nevertheless, it is very unfortunate that no one utilizes the Household Food Consumption Survey data for the estimation of intakes of food additives and contaminants, because that is not the primary purpose of the Japanese National Nutrition Survey.Practically, there are neither foods which have an uniform level of food additives and contaminants nor individuals who consume uniform amounts of each food item. In this report the authors propose a revised estimation method for the daily intake of food contaminants and additives, based on food consumption data of 159 female volunteers, without using the National Nutrition Survey data.The results obtained are as follows:1) This method succeeded in making clear the intakes of food additives and contaminants. Mean, maximum and minimum values and distribution curves for the target population were obtained.2) The suggested name for this method is “Estimated Ecological Daily Intake (EEDI)”, which is processed in terms of the food consumption structure for calculation, and methodologically estimated by food ecology.