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Showing papers on "Reference Daily Intake published in 2009"


Journal ArticleDOI
TL;DR: The Technical Committee on Dietary Lipids of the International Life Sciences Institute North America sponsored a workshop to consider whether the body of evidence specific to the major chronic diseases in the United States--coronary heart disease, cancer, and cognitive decline--had evolved sufficiently to justify reconsideration of DRI for EPA+.
Abstract: There is considerable interest in the impact of (n-3) long-chain PUFA in mitigating the morbidity and mortality caused by chronic diseases. In 2002, the Institute of Medicine concluded that insufficient data were available to define Dietary Reference Intakes (DRI) for eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), noting only that EPA and DHA could contribute up to 10% toward meeting the Adequate Intake for alpha-linolenic acid. Since then, substantial new evidence has emerged supporting the need to reassess this recommendation. Therefore, the Technical Committee on Dietary Lipids of the International Life Sciences Institute North America sponsored a workshop on 4-5 June 2008 to consider whether the body of evidence specific to the major chronic diseases in the United States--coronary heart disease (CHD), cancer, and cognitive decline--had evolved sufficiently to justify reconsideration of DRI for EPA+DHA. The workshop participants arrived at these conclusions: 1) consistent evidence from multiple research paradigms demonstrates a clear, inverse relation between EPA+DHA intake and risk of fatal (and possibly nonfatal) CHD, providing evidence that supports a nutritionally achievable DRI for EPA+DHA between 250 and 500 mg/d; 2) because of the demonstrated low conversion from dietary ALA, protective tissue levels of EPA+DHA can be achieved only through direct consumption of these fatty acids; 3) evidence of beneficial effects of EPA+DHA on cognitive decline are emerging but are not yet sufficient to support an intake level different from that needed to achieve CHD risk reduction; 4) EPA+DHA do not appear to reduce risk for cancer; and 5) there is no evidence that intakes of EPA+DHA in these recommended ranges are harmful.

348 citations


Journal ArticleDOI
TL;DR: This work attempts to identify the most important causes of malnutrition and highlight the most effective nutrition strategies for children with CHD.
Abstract: Growth in children with congenital heart disease (CHD) is often compromised. For several decades, investigators have tried to identify the factors affecting growth in children with CHD. Cardiac malformations are undoubtedly responsible for malnutrition, which may range from mild undernutrition to severe failure to thrive (FTT). Malnutrition may then significantly undermine the outcome of corrective surgical operations and postoperative recovery. Mechanisms linking CHD to malnutrition may be related either to decreased energy intake and/or to increased energy requirements. Decreased energy intake can involve deficiencies of specific nutrients, or insufficient total caloric intake. Increased respiratory rate accompanying congestive heart failure may be responsible for increased energy requirements. Different types of cardiac malformations and consequent interventions may have different effects on growth and require diverse strategies. Most treatment strategies aim to facilitate “catch-up” growth, providing extra calories and protein that exceed the Recommended Dietary Allowance for age. However, there is no generally accepted set of guidelines that define appropriate caloric intake for catch-up growth. We attempt to identify the most important causes of malnutrition and highlight the most effective nutrition strategies for children with CHD.

120 citations


Journal ArticleDOI
TL;DR: It is suggested that 1 of 7 young adults has serum ascorbic acid deficiency, in part, because of unmet recommended dietary intakes, which may have long-term adverse health consequences.
Abstract: A cross-sectional study of the 979 nonsmoking women and men aged 20-29 years who participated in the Toronto Nutrigenomics and Health Study from 2004 to 2008 was conducted to determine the prevalence of serum ascorbic acid (vitamin C) deficiency and its association with markers of chronic disease in a population of young Canadian adults. High performance liquid chromatography was used to determine serum ascorbic acid concentrations from overnight fasting blood samples. A 1-month, 196-item food frequency questionnaire was used to assess dietary intakes. Results showed that 53% of subjects had adequate, 33% had suboptimal, and 14% had deficient levels of serum ascorbic acid. Subjects with deficiency had significantly higher measurements of mean C-reactive protein, waist circumference, body mass index, and blood pressure than did subjects with adequate levels of serum ascorbic acid. The odds ratio for serum ascorbic acid deficiency was 3.43 (95% confidence interval: 2.14, 5.50) for subjects who reported not meeting the recommended daily intake of vitamin C compared with those who did. Results suggest that 1 of 7 young adults has serum ascorbic acid deficiency, in part, because of unmet recommended dietary intakes. Furthermore, serum ascorbic acid deficiency is associated with elevated markers of chronic disease in this population of young adults, which may have long-term adverse health consequences.

108 citations


Journal ArticleDOI
TL;DR: Peripheral oxidative stress markers diminished, and antioxidant markers were enhanced, in WEN after the application of the high antioxidant diet, in comparison to WWE.
Abstract: Oxidative stress has been identified in the peritoneal fluid and peripheral blood of women with endometriosis. However, there is little information on the antioxidant intake for this group of women. The objectives of this work were 1) to compare the antioxidant intake among women with and without endometriosis and 2) to design and apply a high antioxidant diet to evaluate its capacity to reduce oxidative stress markers and improve antioxidant markers in the peripheral blood of women with endometriosis. Women with (WEN, n = 83) and without endometriosis (WWE, n = 80) were interviewed using a Food Frequency Questionnaire to compare their antioxidant intake (of vitamins and minerals). Then, the WEN participated in the application of a control (n = 35) and high antioxidant diet (n = 37) for four months. The high antioxidant diet (HAD) guaranteed the intake of 150% of the suggested daily intake of vitamin A (1050 μg retinol equivalents), 660% of the recommended daily intake (RDI) of vitamin C (500 mg) and 133% of the RDI of vitamin E (20 mg). Oxidative stress and antioxidant markers (vitamins and antioxidant enzymatic activity) were determined in plasma every month. Comparison of antioxidant intake between WWE and WEN showed a lower intake of vitamins A, C, E, zinc, and copper by WEN (p < 0.05, Mann Whitney Rank test). The selenium intake was not statistically different between groups. During the study, the comparison of the 24-hour recalls between groups showed a higher intake of the three vitamins in the HAD group. An increase in the vitamin concentrations (serum retinol, alpha-tocopherol, leukocyte and plasma ascorbate) and antioxidant enzyme activity (superoxide dismutase and glutathione peroxidase) as well as a decrease in oxidative stress markers (malondialdehyde and lipid hydroperoxides) were observed in the HAD group after two months of intervention. These phenomena were not observed in the control group. WEN had a lower intake of antioxidants in comparison to WWE. Peripheral oxidative stress markers diminished, and antioxidant markers were enhanced, in WEN after the application of the HAD.

105 citations


Journal ArticleDOI
TL;DR: New Dietary Reference Intakes for folate, including the Recommended Dietary Allowance, recently have been reported by the National Academy of Sciences.
Abstract: New Dietary Reference Intakes (DRIs) for folate, including the Recommended Dietary Allowance, recently have been reported by the National Academy of Sciences. These new DRIs are summarized and the scientific basis and approach used to determine the recommended intake levels for folate are discussed.

92 citations


Journal ArticleDOI
TL;DR: Fresh fruit and vegetable distribution programs provide the opportunity for students to taste a variety of fruits and vegetables, and may improve consumption of these foods by adolescents.
Abstract: Low fruit and vegetable intake may be associated with overweight. The United States Department of Agriculture implemented the Fresh Fruit and Vegetable Program in 2006-2007. One Houston-area high school was selected and received funding to provide baskets of fresh fruits and vegetables daily for each classroom during this period. This study assessed the impact of the program on students' fruit and vegetable intake. At program end (May 2007), fruit and vegetable intake surveys were distributed to students at the intervention school as well as at a comparison high school that did not receive the program. Surveys, which were completed anonymously, were received from 34% of intervention and 42% of comparison school students. The students were classified as to whether they met the recommended daily intake of fruit, 100% fruit juice, and vegetables. The probability of meeting the recommendations was assessed with logistic regression analyses, controlling for sex, age, and ethnicity. Compared with the comparison control school students, intervention school students were more likely to report eating fruit and drinking 100% fruit juice at least two times per day (39.3% vs 27.3%; P<0.05) and consuming total fruit, juice, and vegetables (22% vs 18.4%; P<0.05) five or more times per day in the preceding 7 days. More intervention school students (59.1%) than comparison school students (40.9%) reported eating fruit at least one time per day (P<0.05). There were no group differences in vegetable intake. Fresh fruit and vegetable distribution programs provide the opportunity for students to taste a variety of fruits and vegetables, and may improve consumption of these foods by adolescents.

92 citations


Journal ArticleDOI
TL;DR: A review of the scientific literature suggests that the current recommended dietary allowance for calcium may not be high enough to optimize the genetically programmed peak bone mass in a substantial number of growing individuals.
Abstract: Peak adult bone mass is determined in each individual by a combination of endogenous and environmental factors. Insufficient accumulation of skeletal mass by the time young adulthood is reached appears to enhance the likelihood of fractures later in life. It is speculated that environment (nutrition and exercise) contributes to about 20% of the variance in bone mass. Although much is yet to be learned about how diet contributes to skeletal growth and development, it now appears that calcium intake may be an important factor in the attainment of peak bone mass. A review of the scientific literature suggests that the current recommended dietary allowance (RDA) for calcium may not be high enough to optimize the genetically programmed peak bone mass in a substantial number of growing individuals. New standards for dietary calcium intakes during growth may be indicated.

91 citations


Journal ArticleDOI
TL;DR: These overweight adults diagnosed with diabetes are exceeding recommended intake of fat, saturated fats, and sodium, which may contribute to increasing their risk of cardiovascular disease and other chronic diseases.
Abstract: Background Little has been reported regarding food and nutrient intake in individuals diagnosed with type 2 diabetes, and most reports have been based on findings in select groups or individuals who self-reported having diabetes. Objective To describe the baseline food and nutrient intake of the Look AHEAD (Action for Health in Diabetes) trial participants, compare participant intake to national guidelines, and describe demographic and health characteristics associated with food group consumption. Methods The Look AHEAD trial is evaluating the effects of a lifestyle intervention (calorie control and increased physical activity for weight loss) compared with diabetes support and education on long-term cardiovascular and other health outcomes. Participants are 45 to 75 years old, overweight or obese (body mass index [BMI]≥25), and have type 2 diabetes. In this cross-sectional analysis, baseline food consumption was assessed by food frequency questionnaire from 2,757 participants between September 2000 and December 2003. Statistical analysis Descriptive statistics were used to summarize intake by demographic characteristics. Kruskal-Wallis tests assessed univariate effects of characteristics on consumption. Multiple linear regression models assessed factors predictive of intake. Least square estimates were based on final models, and logistic regression determined factors predictive of recommended intake. Results Ninety-three percent of the participants exceeded the recommended percentage of calories from fat, 85% exceeded the saturated fat recommendation, and 92% consumed too much sodium. Also, fewer than half met the minimum recommended servings of fruit, vegetables, dairy, and grains. Conclusions These participants with pre-existing diabetes did not meet recommended food and nutrition guidelines. These overweight adults diagnosed with diabetes are exceeding recommended intake of fat, saturated fats, and sodium, which may contribute to increasing their risk of cardiovascular disease and other chronic diseases.

87 citations


Journal Article
TL;DR: The results indicated that, in 2005--2006, the lower sodium recommendation was applicable to 69.2% of U.S. adults, and consumers and health-care providers should be aware of the lower Sodium recommendation.
Abstract: In 2005-2006, an estimated 29% of U.S. adults had hypertension (i.e., high blood pressure), and another 28% had prehypertension. Hypertension increases the risk for heart disease and stroke, the first and third leading causes of death in the United States. Greater consumption of sodium can increase the risk for hypertension. The main source of sodium in food is salt (sodium chloride [NaCl]); uniodized salt is 40% sodium by weight. In 2005--2006, the estimated average intake of sodium among persons in the United States aged >/=2 years was 3,436 mg/day. In 2005, the U.S. Department of Health and Human Services and U.S. Department of Agriculture recommended that adults in the United States should consume no more than 2,300 mg/day of sodium (equal to approximately 1 tsp of salt), but those in specific groups (i.e., all persons with hypertension, all middle-aged and older adults, and all blacks) should consume no more than 1,500 mg/day of sodium. To estimate the proportion of the adult population for whom the lower sodium recommendation is applicable, CDC analyzed data from the National Health and Nutrition Examination Survey (NHANES) for the period 1999--2006. The results indicated that, in 2005--2006, the lower sodium recommendation was applicable to 69.2% of U.S. adults. Consumers and health-care providers should be aware of the lower sodium recommendation, and health-care providers should inform their patients of the evidence linking greater sodium intake to higher blood pressure.

87 citations


Journal ArticleDOI
TL;DR: Eating low- density foods in the morning and avoiding high-density foods at night might aid in reducing overall intake and may be useful in dietary interventions for overweight and obesity.
Abstract: Intake in the morning is associated with a reduction in the total intake for the day, while intake at night is associated with greater overall daily intake. These associations are macronutrient specific, with morning carbohydrate intake associated with reduced daily carbohydrate intake, morning fat intake associated with reduced daily fat intake and morning protein intake associated with reduced daily protein intake. Since different types of foods contain differing proportions of macronutrients, the present study investigated the associations of different types of foods ingested at various times of day with total daily and macronutrient intakes. The intakes of 388 male and 621 female free-living individuals reported in 7 d diet diaries were reanalysed. The intakes of twenty-four different types of foods and seven different drinks occurring during the morning (04.00-10.29 hours), afternoon (10.30-16.59 hours) and evening (17.00-02.00 hours) were identified and related to overall daily intakes. Dairy foods, ice cream, beef, other meats, potatoes, pastry, nuts, chips and snacks, condiments, alcohol and soda were significantly associated with higher total intake over the day, while fruit, soup, breakfast cereal, pasta, pizza, water, coffee/tea and diet soda were either not associated or were associated with lower overall intake. Dietary energy density appeared to mediate the associations between particular foods and beverages and overall energy intake. This suggests that eating low-density foods in the morning and avoiding high-density foods at night might aid in reducing overall intake and may be useful in dietary interventions for overweight and obesity.

79 citations


Journal ArticleDOI
TL;DR: Pregnant women in this rural area of Burkina Faso do not seem to restrict their diet significantly during pregnancy, and the additional nutritional requirements of pregnancy are not accounted for in their dietary practises.
Abstract: The aim of this study was to assess potential changes in dietary habits during pregnancy in a rural community in Hounde district, Burkina Faso. In-depth interviews were performed on a random sample of 37 pregnant women in order to analyse specific perceptions and attitudes regarding food consumption during pregnancy. In addition to this, an interactive 24-h recall survey was used to compare the food intake of 218 pregnant and 176 non-pregnant women. The majority of interviewees reported dietary restrictions during pregnancy but no consistent pattern of avoided food types was found. Most of the mentioned 'forbidden' foods were in related to physical discomfort during gestation. Interviewees also admitted to ignoring culturally determined food prohibitions/prescriptions. No differences were observed in food intake, food choice and nutrient intake between the group of pregnant and non-pregnant women. During the third trimester of gestation women did not show any major differences in food and nutrient intake compared with women from the first/second trimester. The mean nutrient intakes were found to be insufficient compared with the recommended daily allowances, especially for pregnant women. In conclusion, pregnant women in this rural area of Burkina Faso do not seem to restrict their diet significantly during pregnancy. The additional nutritional requirements of pregnancy are not accounted for in their dietary practises.

Journal ArticleDOI
TL;DR: Children with T1D are not meeting dietary guidelines, and in some areas their diets are less healthful than children without diabetes, so the incorporation of behavioral approaches promoting healthy eating into routine clinical practice is warranted.
Abstract: Purpose The purpose of this study is to review the literature on usual dietary intake in children with type 1 diabetes (T1D) and to discuss approaches to promote dietary change with potential efficacy. Methods Search strategies included a MEDLINE search for English-language articles that estimated usual dietary intake in children with T1D and a screening of the reference lists from original studies. The keywords used were diet, dietary intake, nutrition, type 1 diabetes, children, adolescents, and youth. Studies were included if they were observational, contained a sample of children with T1D, and estimated usual dietary intake. Results Nine studies fulfilled the criteria (6 US, 3 European). Of the 4 studies with a control group, 3 reported that both total fat and saturated fat intake were higher in the children with T1D. Six studies examined the percent of total calories from saturated fat; mean intake ranged from 11 to 15%, exceeding ADA recommendations (< 7%). Fruit, vegetable, and fiber intakes were low among children with T1D. No prior studies have addressed dietary change in this population. The behavior-change literature suggests that nutrition education alone is unlikely to be adequate, but that incorporation of behavioral approaches offers potential efficacy in promoting healthful dietary change. Conclusions Children with T1D are not meeting dietary guidelines, and in some areas their diets are less healthful than children without diabetes. As these dietary behaviors may affect the risk of long-term complications, the incorporation of behavioral approaches promoting healthy eating into routine clinical practice is warranted.

Journal ArticleDOI
TL;DR: The role of polyphenols in human nutrition is discussed on the basis of their redox chemistry, which accounts for the observed antioxidant effect and in turn for their protective effect against atherosclerosis.
Abstract: The role of polyphenols in human nutrition is discussed on the basis of their redox chemistry, which accounts for the observed antioxidant effect and in turn for their protective effect against atherosclerosis. Epidemiologic data, together with experimental pathology and cell biology, support the recommendation that optimal nutrition should contain polyphenols in amounts that may better described as a “Recommended Optimal Intake” (ROI) than as a “Recommended Dietary Allowance” (RDA). Because a valid procedure to identify polyphenols in plasma is not available, analysis of plasma antioxidant capacity is instead suggested as a suitable index to define the optimal nutritional intake.

Journal ArticleDOI
TL;DR: Estimates of daily per capita vitamin A intake expressed in RE in Africa, South America, and Asia are reduced from 895, 599, and 667, respectively, to 371, 372, and 258, respectively.
Abstract: When the intake of foods or pharmaceutical preparations containing sufficient nutrients of adequate bioavailability are consumed, nutrient requirements are met and optimal nutritional status is maintained. Recent studies have shown that the basis for describing vitamin A activity of carotenoids overestimates the bioavailability of provitamin A carotenoids and their bioconversion to retinol (vitamin A). It is therefore proposed that instead of 6 pg from a mixed diet, 21 μg β-carotene are required to provide 1 μg of retinol or 1 RE (retinol equivalent) of vitamin A. Based on this assumption and on data from food balance sheets, estimates of daily per capita vitamin A intake expressed in RE in Africa, South America, and Asia are reduced from 895, 599, and 667, respectively, to 371, 372, and 258, respectively. Such intakes are well below the recommended daily intake of 600 RE for adult males. A new combination of approaches will therefore have to be used to combat vitamin A deficiency rather than that used up until now.

Journal ArticleDOI
TL;DR: Results showed that SFA intakes in Irish children, teenagers and adults are high, with only 6 % of children, 11 % of teenagers and 21 % of adults in compliance with the recommended daily intake.
Abstract: Recommendations limiting the intake of total fat, SFA, MUFA and PUFA have been established in several countries with the aim of reducing the risk of chronic diseases such as CVD. Studies have shown that intakes of total fat and SFA are above desired recommended intake levels across a wide range of age and sex groups. In addition, intakes of PUFA and MUFA are often reported to be less than the desired recommended intake levels. The aims of the present paper are to provide the first data on estimates of current intakes and main food sources of SFA, MUFA and PUFA in Irish children (aged 5–12 years), teenagers (aged 13–17 years) and adults (aged 18–64 years) and to analyse compliance with current dietary recommendations. Data for this analysis were based on the North/South Ireland Food Consumption Survey (n 1379, 18–64 years), the National Children’s Food Survey (n 594, 5–12 years) and the National Teen Food Survey (n 441, 13–17 years). Results showed that SFA intakes in Irish children, teenagers and adults are high, with only 6 % of children, 11 % of teenagers and 21 % of adults in compliance with the recommended daily intake. The main food groups that contributed to SFA intakes were whole milk; fresh meat; meat products; biscuits, cakes, buns and pastries; and sugars, confectionery and preserves.

Journal ArticleDOI
TL;DR: Korean diet is high in plant foods but also high in salted vegetables, so relations between intakes of salted and non-salted vegetables and so on are analyzed.
Abstract: Korean diet is high in plant foods but also high in salted vegetables. World Cancer Research Fund (WCRF) recommends consumption of fruits and vegetables excluding salted vegetables for prevention cancer. This study aimed to analyze relations between intakes of salted and non-salted vegetables and so...

Journal ArticleDOI
TL;DR: The severe deficiency in vitamin intake among women and rural dwellers and marked differences in nutrient intake between rural and urban dwellers may contribute to the observed epidemiological pattern of EC in Golestan, with high incidence rates among women, people with low socioeconomic status and the highest incidence rate among rural women.
Abstract: Our objectives were to investigate patterns of food and nutrient consumption in Golestan province, a high-incidence area for esophageal cancer (EC) in northern Iran Twelve 24-h dietary recalls were administered during a 1-yr period to 131 healthy participants in a pilot cohort study We compare here nutrient intake in Golestan with recommended daily allowances (RDAs) and lowest threshold intakes (LTIs) We also compare the intake of 27 food groups and nutrients among several population subgroups using mean values from the 12 recalls Rural women had a very low level of vitamin intake, which was even lower than LTIs (P < 001) Daily intake of vitamins A and C was lower than LTI in 67% and 73% of rural women, respectively Among rural men, the vitamin intakes were not significantly different from LTIs Among urban women, the vitamin intakes were significantly lower than RDAs but were significantly higher than LTIs Among urban men, the intakes were not significantly different from RDAs Compared to urban dwellers, intake of most food groups and nutrients, including vitamins, was significantly lower among rural dwellers In terms of vitamin intake, no significant difference was observed between Turkmen and non-Turkmen ethnics The severe deficiency in vitamin intake among women and rural dwellers and marked differences in nutrient intake between rural and urban dwellers may contribute to the observed epidemiological pattern of EC in Golestan, with high incidence rates among women and people with low socioeconomic status and the highest incidence rate among rural women

Journal ArticleDOI
TL;DR: The findings support continued efforts by oncology nurses to identify the types of supplements cancer survivors are using and caution nurses against the use of individual supplements as well as combinations of different supplements containing nutrient quantities above recommended daily intake levels.
Abstract: Purpose/objectives To assess dietary supplement use and its association with demographic and health-related characteristics among cancer survivors and to investigate differences in supplement use patterns by cancer site. Design A cross-sectional survey. Setting Computer-assisted telephone survey. Sample 1,233 adult (ages 30-69) survivors participating in the Penn State Cancer Survivor Study who underwent an interviewer-administered questionnaire. Methods Descriptive statistics with multivariate logistic regression to determine demographic, disease, and health-related predictors of supplement use. Main research variables Use of dietary supplements and types of supplements taken. Findings Supplement use ranged from 50% among blood cancer survivors to 85% among melanoma skin cancer survivors, with an overall prevalence rate of 73%. Multivariate logistic regression revealed statistically significant associations (p values or= age 50), higher levels of education and physical activity, female gender, lower body mass index, and white ethnicity. Conclusions Overall, a wide variety of supplements were reported, although multivitamins, calcium and vitamin D combinations, and antioxidant vitamin combinations were the most prevalent. Seventy-eight percent of supplement users took more than one supplement. Implications for nursing The findings support continued efforts by oncology nurses to identify the types of supplements cancer survivors are using. Nurses should caution against the use of individual supplements as well as combinations of different supplements containing nutrient quantities above recommended daily intake levels. Furthermore, oncology nurses and other healthcare professionals should be receptive to questions and prepared to initiate conversations with patients about their use of dietary supplements.

Journal ArticleDOI
TL;DR: In 2004, the mean calcium intake of Canadians was below Dietary Reference Intake recommendations for most adults, with the greatest difference in older adults (>or=51 years), in part because the recommended calcium intake for this group is higher than that for younger adults.
Abstract: The objective of this study was to determine trends in calcium intake from foods of Canadian adults from 1970–1972 to 2004. We compiled the calcium intake of adults (aged ≥19 years) from foods from Nutrition Canada (1970–1972; n = 7036); 9 provincial nutrition surveys (1990–1999; n = 16 915); and the 2004 Canadian Community Health Survey 2.2 (n = 20 197). Where possible, we used published confidence intervals to test for significant differences in calcium intake. In 2004, the mean calcium intake of Canadians was below Dietary Reference Intake recommendations for most adults, with the greatest difference in older adults (≥51 years), in part because the recommended calcium intake for this group is higher (1200 mg) than that for younger adults (1000 mg). The calcium intake of males in every age category was greater than that of females. Calcium intake increased from 1970 to 2004, yet, despite the introduction of calcium-fortified beverages to the market in the late 1990s, increases in calcium intake between ...

Journal ArticleDOI
TL;DR: Magnesium, calcium and iron intake may possibly be related to MS disease progression, and should receive further attention because no effective neuroprotective treatment for patients is available.
Abstract: Backround: Multiple sclerosis is a neurodegenerative disorder with a wide range in disease course severity. Many factors seem to be implicated in multiple sclerosis disease course, and diet has been suggested to play a role. Because limited data is present in the literature it was investigated whether variations in dietary intake may be related to the severity of the disease course in multiple sclerosis. Methods: Using a food diary during 14 days, the dietary intake of 23 nutrients and vitamins was measured in patients with primary progressive (n = 21), secondary progressive (n = 32), and benign multiple sclerosis (n = 27) and compared to each other. The intake measured was also compared to the intake of the Dutch population and to the recommended daily allowance. Results: Compared to the other MS groups, the secondary progressive MS patients had a lower intake of magnesium, calcium and iron. The total group of MS patients had, compared to the Dutch population, a lower intake of folate, magnesium and copper and a lower energy intake. Compared to the daily recommended allowance, the MS patients had a lower than recommended intake of folic acid, magnesium, zinc and selenium. Conclusion: Magnesium, calcium and iron intake may possibly be related to MS disease progression, and should receive further attention. This is important because no effective neuroprotective treatment for MS patients is available.

Journal ArticleDOI
TL;DR: Child swimmers improved the redox status of glutathione during training, although the intake of antioxidant nutrients did not change, suggesting the need for nutritional monitoring and education of children athletes.

Journal ArticleDOI
TL;DR: Age, gender and intake of fresh fish liver oil were significant predictors of three of the most common PCBs and trans-Nonachlor in this study group and intakes of fatty fish did not significantly affect the body burden of POPs.
Abstract: There are strong indications that a moderate intake of fatty fish decreases the risk of cardiovascular diseases due to its content of omega-3 fatty acids. Other studies indicate that fatty fish consumption increase the body burden of Persistent Organic Pollutants (POPs) and may thereby increase the risk of negative health effects. Many of the latter studies are based on POP analysis of fatty fish, from which a recommended daily intake for humans has been calculated based on the no-observed adverse effect level (NOAEL) obtained from animal studies. Studies investigating associations between human plasma concentrations of POPs and intake of marine food show deviating results. In this study we investigated associations between self-reported intake of marine food (fatty fish, fish liver, fish liver oil, seagull eggs and halibut) and plasma concentrations of POPs. The study group consisted of 44 women and 16 men from northern Norway with a marine based diet. In addition to donate blood samples, the participants answered a detailed food frequency questionnaire with special emphasis on marine food consumption. Concentrations of 25 different POPs were measured in plasma. PCB 153 and p′p-DDE were the most ubiquitous PCB and chlorinated pesticide and the geometric mean concentrations were 73 ng/g lipids and 116 ng/g lipids respectively. The main findings in this study were that age, gender and intake of fresh fish liver oil were significant predictors of three of the most common PCBs and trans-Nonachlor in this study group. In addition, intake of seagull eggs influenced the concentration of PCB 180. However, even though the participants had a high intake of marine food they did not have elevated levels of POPs compared to other study groups. Intake of fatty fish did not significantly affect the body burden of POPs in this study group.

Journal ArticleDOI
TL;DR: Though their intakes decrease with increasing age, so do their energy expenditure, making their relative insufficiency of food intake stable with age, and these community living elderly suffer from lack of both macronutrient intake as compared with energy requirements, and micronutrients intake asCompared with the standard dietary recommendations.
Abstract: Aging is a process associated with physiological changes such as in body composition, energy expenditure and physical activity. Data on energy and nutrient intake adequacy among elderly is important for disease prevention, health maintenance and program development. This descriptive cross-sectional study was designed to determine the energy requirements and adequacy of energy and nutrient intakes of older persons living in private households in a rural Filipino community. Study participants were generally-healthy, ambulatory, and community living elderly aged 60–100 y (n = 98), 88 of whom provided dietary information in three nonconsecutive 24-hour food-recall interviews. There was a decrease in both physical activity and food intake with increasing years. Based on total energy expenditure and controlling for age, gender and socio-economic status, the average energy requirement for near-old (≥ 60 to < 65 y) males was 2074 kcal/d, with lower requirements, 1919 and 1699 kcal/d for the young-old (≥ 65 to < 75 y) and the old-old (≥ 75 y), respectively. Among females, the average energy requirements for the 3 age categories were 1712, 1662, and 1398 kcal/d, respectively. Actual energy intakes, however, were only ~65% adequate for all subjects as compared to energy expenditure. Protein, fat, and micronutrients (vitamins A and C, thiamin, riboflavin, iron and calcium) intakes were only ~24–51% of the recommended daily intake. Among this population, there was a weight decrease of 100 g (p = 0.012) and a BMI decrease of 0.04 kg/m2 (p = 0.003) for every 1% decrease in total caloric intake as percentage of the total energy expenditure requirements. These community living elderly suffer from lack of both macronutrient intake as compared with energy requirements, and micronutrient intake as compared with the standard dietary recommendations. Their energy intakes are ~65% of the amounts required based on their total energy expenditure. Though their intakes decrease with increasing age, so do their energy expenditure, making their relative insufficiency of food intake stable with age.

Patent
15 Jul 2009
TL;DR: A dietary supplement composition having an ORAC value in excess of at least about 2,500 and which can be readily consumed in a small quantity is provided for supplementing an individual's daily intake.
Abstract: A dietary supplement composition having an ORAC value in excess of at least about 2,500 and which can be readily consumed in a small quantity is provided for supplementing an individual's daily intake. The dietary supplement composition suitably includes organic and/or vegan ingredients and can be consumed in quantities of as little as about 1 tablespoon to provide an amount of antioxidants equivalent to at least the minimum recommended daily intake of five to nine servings of fruits and/or vegetables.

Journal ArticleDOI
TL;DR: Trends in dietary supplement use and its contribution to total nutrient intake in the Iowa Women's Health Study cohort in 1986 and 2004 were examined, and intake of many nutrients increased, primarily because of the rising use of dietary supplements.
Abstract: Although it is widely known that use of dietary supplements is common in the United States, little is known about use patterns among older Americans. The authors examined trends in dietary supplement use and its contribution to total nutrient intake in the Iowa Women's Health Study cohort in 1986 (baseline) and 2004 (follow-up). The proportion of women who reported using dietary supplements increased substantially between baseline (66%) and follow-up (85%). Moreover, a substantial proportion of women reported using multiple dietary supplements, with 27% using 4 or more products in 2004. Dietary supplements contributed substantially to total intake of many nutrients at baseline, and their contribution became relatively greater at follow-up for most nutrients examined. For most nutrients, no decline in intake was observed, as might have been expected in an aging cohort. Rather, intake of many nutrients increased, primarily because of the rising use of dietary supplements. Use of dietary supplements by older individuals is of particular importance because of the potential benefits of maintaining nutrient intake levels despite potentially declining food intake. However, possible risks from obtaining a large proportion of purified nutrients from dietary supplements rather than deriving them from foods should be studied.

Journal ArticleDOI
TL;DR: An iron supplement of 16 mg/d throughout pregnancy is justified as both efficacious and safe for healthy women living in Canadian households and does not preclude the need for therapeutic iron doses for some individuals on the basis of iron status.

Journal Article
TL;DR: Investigation of how a long-term vitamin-mineral supplementation following the US Recommended Daily Intake affected the plasma levels of selected nutrients in a subset of participants in the Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract found the effect of supplementation was significantly higher in participants with lower nutritional status at baseline.
Abstract: The use of multivitamin-mineral supplements has become increasingly common, but whether the use of such supplements improves micronutrient status remains still unclear. The objective of this report is to investigate how a long-term vitamin-mineral supplementation following the US Recommended Daily Intake (RDI) affected the plasma levels of selected nutrients in a subset (No. = 407) of participants in the Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS). The CTNS was a double-blind, single centre, controlled clinical trial of 1020 participants aged 55-75 years randomized to a daily tablet of Centrum(R) or placebo. A representative sample of 40% of the 1020 subjects, whom plasma level of selected vitamins was determined at the baseline, was retested throughout the treatment period that averaged 9.0 +/- 2.4 years. Participants assigned to Centrum(R) showed a significant increase (p < 0.005) in mean/median plasma levels of vitamin E, beta-carotene, folate, and vitamin B12, and an improved riboflavin status when compared with participants assigned to placebo. Differences concerning vitamin C were statistically less relevant and those concerning vitamin A were at a borderline level. In the treated group the effect of supplementation on plasma levels of vitamins A, E, and C, and on the glutathione reductase activation coefficient was significantly higher in participants with lower nutritional status at baseline.

Journal ArticleDOI
TL;DR: Fruit, vegetable, fish and dairy, as well as vitamin D supplement, need to be increased in the diet of 7-year-old children to reach the FBDG and the reference values for nutrient intake.
Abstract: OBJECTIVE: To evaluate the diet of 7-year-old children by comparison with food-based dietary guidelines (FBDG) and reference values for nutrient intake. DESIGN: Food and nutrient intake was assessed by 3 d weighed dietary records of 7-year-olds in six randomly chosen schools in Reykjavik, Iceland. Height and weight were measured. The diet of 165 children (62 % of sample) was evaluated by the Icelandic FBDG and the Nordic reference values (NRV) for nutrient intake. SETTING: Six randomly chosen schools in Reykjavik, Iceland. RESULTS: The FBDG on fruits and vegetables was reached by less than 20 % of the children. A total of 52 % reached the FBDG to eat fish twice a week and 41 % to use vitamin D supplement. The FBDG on dairy was reached by 66 % of the children. Mean intake of SFA gave 13.9 % of the total energy intake (E%), which is higher than the NRV, 9.3E% of MUFA and 3.8E% of PUFA, both lower than the NRV (for all differences P < 0.001). Added sugar gave 12.1E%, which exceeds the upper level (P < 0.001). Fibre intake was 2.1 g/MJ and lower than the NRV (P < 0.001). Mean intake of micronutrients was above the recommended intake (RI), except for iodine, 109.0 microg/d, and vitamin D, 6.1 microg/d, which was lower than the RI (P = 0.006 and P < 0.001, respectively). CONCLUSIONS: Fruit, vegetable, fish and dairy, as well as vitamin D supplement, need to be increased in the diet of 7-year-old children to reach the FBDG and the reference values for nutrient intake. Dietary changes to increase the quality of fat and carbohydrate are needed as well.

01 Jan 2009
TL;DR: The Panel on Dietetic Products, Nutrition and Allergies was asked to review and provide advice on labelling reference intakes for energy, fat, saturates, carbohydrate, sugars and salt that are included in a proposal for a Regulation of the European Parliament and the Council on the provision of food information to the consumer.
Abstract: SUMMARY Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to review and provide advice on labelling reference intakes for energy, fat, saturates (saturated fat), carbohydrate, sugars and salt that are included in a proposal for a Regulation of the European Parliament and the Council on the provision of food information to the consumer (COM(2008) 40). The proposed labelling reference intakes for energy and nutrients are to be used to enable the nutrient content of a food product (per 100 g, per 100 ml, or per portion) to be expressed as a percentage of a typical recommended daily intake (adults). This information allows comparison of the nutritional values of food products and can help to convey the relative significance of the food as a source of energy and nutrients in the context of a total daily diet. For practical application in nutrition labelling, a single reference intake is proposed for each nutrient using rounded values for ease of calculation. Labelling reference intakes for total fat, saturated fat, carbohydrate, sugars and salt may be derived from science-based nutrient intake recommendations for the general population that have been established by national and international authorities. For these nutrients, intake recommendations for the general population are based on evidence of relationships between intake and the risk of obesity and/or diet-related diseases (e.g. cardiovascular disease, diabetes mellitus, dental caries). The nutrient intake recommendations for the general population established by authorities in different EU countries are generally consistent (but not uniform). It is important to distinguish the labelling reference intakes for nutrients from dietary reference values established for population groups.

Journal ArticleDOI
TL;DR: The main objective of as discussed by the authors was to determine the nutritional value and the total dietary antioxidant capacity (TDAC) of lunch meals consumed by elderly people attending a day-care centre in Sharpeville, South Africa.