Topic
Salinispora arenicola
About: Salinispora arenicola is a research topic. Over the lifetime, 66 publications have been published within this topic receiving 4122 citations.
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TL;DR: Arenimycin, an antibiotic effective against rifampin-and methicillin-resistant Staphylococcus aureus from the marine actinomycete Salinispora arenicola as mentioned in this paper.
Abstract: Arenimycin, an antibiotic effective against rifampin- and methicillin-resistant Staphylococcus aureus from the marine actinomycete Salinispora arenicola
4 citations
TL;DR: Three new 3-hydroxy-N-methyl-2-oxindole (1 and 2) and 4-Hydroxy-pyran- 2-one (3) derivatives, along with the known 3- Hydrolysis-Methoxy-N -methyl-3-methylisatin derivatives, were isolated from a marine Salinispora arenicola strain from sediments of the St. Peter and St. Paul Archipelago, Brazil.
4 citations
TL;DR: In this paper, an ansamycin, rifamycin W, and three phenylethylamides, N-(2'-phenylethyl)isobutyramide, 2-methyl-N-(2"-phenylethsyl)butyramides, and N-( 2'-phenylthyl)-isovaleramide were isolated from the fermentation broth of amarine actinomycete strain identified as Salinispora arenicola.
Abstract: An ansamycin, rifamycin W, and three phenylethylamides, N-(2'-phenylethyl)isobutyramide, 2-methyl-N-(2'-phenylethyl)butyramide, and N-(2'-phenylethyl)isovaleramide were isolated from the fermentation broth of amarine actinomycete strain identified as Salinispora arenicola. The structures of these compounds were confirmed by detailed interpretation of NMR spectroscopic and high resolution ESILC-MS data. Moderate antibacterial activity was observed for rifamycin W only.
4 citations
TL;DR: The synthesis of stereochemical analogs of arenamide A, a 19-membered cytotoxic depsipeptide isolated from the fermentation broth of a marine bacterial strain Salinispora arenicola, and HATU mediated macrolactamization are described.
4 citations
TL;DR: In this paper, a planar structure of 26-membered polyunsaturated macrolactones containing repeating vicinal hydroxyl methoxyl moieties of the obligate marine actinomycete Salinispora arenicola was elucidated via spectroscopic and chemical methods.
Abstract: Chemical evaluation of the saline fermentation broth of several strains of the obligate marine actinomycete Salinispora arenicola has led to the identification of three new macrolide polyketides designated arenicolides A-C (1-3). The planar structures, elucidated via spectroscopic and chemical methods, consist of 26-membered polyunsaturated macrolactones containing repeating vicinal hydroxyl methoxyl moieties. The relative and absolute stereochemistries of 1-3 were assigned by a combination of J-based configurational analyses and chemical derivatization.
4 citations