Topic
Sclera
About: Sclera is a research topic. Over the lifetime, 3583 publications have been published within this topic receiving 71062 citations. The topic is also known as: white of the eye.
Papers published on a yearly basis
Papers
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TL;DR: It seems that the thickening of the choroid may be mechanistically linked to the scleral synthesis of macromolecules, and thus may play an important role in the homeostatic control of eye growth, and, consequently, in the etiology of myopia and hyperopia.
1,356 citations
Book•
01 Jan 1989
TL;DR: Ocular side-effects of systemic medication 21.1.
Abstract: 1. Eyelids 2. Lacrimal Drainage System 3. Orbit 4. Dry Eye Disorders 5. Conjunctiva 6. Cornea 7. Corneal and Refractive Surgery 8. Episclera and Sclera 9. Lens 10. Glaucoma 11. Uveitis 12. Ocular Tumours 13. Retinal Vascular Disease 14. Acquired Macular Disorders 15. Hereditary Fundus Dystrophies 16. Retinal Detachment 17. Vitreous Opacities 18. Strabismus 19. Neuro-ophthalmology 20. Ocular side-effects of systemic medication 21. Trauma Index
1,025 citations
Journal Article•
TL;DR: The organization of collagen fibrils in the human cornea and sclera was studied by scanning electron microscope, after digestion of cellular elements by sodium hydroxide, and by conventional transmission electron microscopy.
Abstract: The organization of collagen fibrils in the human cornea and sclera was studied by scanning electron microscopy, after digestion of cellular elements by sodium hydroxide, and by conventional transmission electron microscopy. The collagen fibrils in the cornea had a uniform diameter of about 25 nm. In Bowman's layer, individual collagen fibrils were interwoven densely to form a felt-like sheet. In the stroma, most of the collagen fibrils ran abreast in lamellae, with varying widths and thickness. These lamellae were arranged basically parallel to the corneal surface but often communicated with those of adjacent layers by interchanging their fibrils. In the innermost stromal region adjacent to Descemet's membrane, collagen fibrils were oriented in various directions and interlaced, forming loose fibrillar networks. The sclera, however, was composed of collagen fibrils with various diameters ranging from 25-230 nm. Although these collagen fibrils formed bundles, they were not parallel but were entangled in individual bundles. These collagen bundles varied in width and thickness, often gave off branches, and intertwined with each other.
694 citations
TL;DR: A comprehensive database of ocular tissue permeability measurements found in a review of the literature to guide models for drug transport in the eye was collected and the corneal epithelium was shown generally to control transcorneal transport.
584 citations
Book•
15 Jan 1996
TL;DR: The Eye.
Abstract: The Eye. Conjunctiva. Cornea. Sclera. Lens. Glaucoma. Optic Nerve. Vitreous. Retina. The Uveal Tract. Eyelids and Lacrimal Drainage System. Orbit. Basic Mechanisms in Pathology.
561 citations