Topic
Selenium
About: Selenium is a research topic. Over the lifetime, 21192 publications have been published within this topic receiving 429715 citations. The topic is also known as: Se & selen.
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TL;DR: The GPX4c718t SNP both alters protein binding to the 3'UTR in vitro and influences the concentration of lymphocyte GPx4 and other selenoproteins in vivo and, at low selenium intake, the SNP thus may influence susceptibility to disease.
100 citations
TL;DR: Using polyclonal monospecific antibodies to purified erythrocyte GSHPx, the relationship between enzymatic activity and protein content was determined and it was found that selenium deficiency results not only in a decrease of G SHPx activity, but also in a decreases of GSHpx protein.
Abstract: Glutathione peroxidase (GSHPx) activity is an indicator of selenium status in selenium-deficient individuals. Utilizing polyclonal monospecific antibodies to purified erythrocyte GSHPx, we were able to determine the relationship between enzymatic activity and protein content. In erythrocytes from a selenium-deficient individual who was treated with selenium, and in HL-60 cells grown in the absence of selenium and then returned to selenium-containing medium, there was a direct relationship between enzymatic activity and protein content. Thus, selenium deficiency results not only in a decrease of GSHPx activity, but also in a decrease of GSHPx protein.
100 citations
TL;DR: The understanding of mining-related selenium occurrence in surface water, soil and plant is updated, with a focus on its mobility and bioavailability, with the introduction of new policies for Se monitoring in the mining industry.
100 citations
TL;DR: Selenomethionine was the main selenium-containing amino acid identified in most of the extracts by HPLC-ICP-MS, and the higher values were 6.8 and 14.5 mg x kg(-)(1) (expressed as Se in dry matter) in the leaves of lupine and sunflower, respectively.
Abstract: Selenium has been recognized as essential for all mammals; therefore, its concentration level and speciation are of great concern. Plants are one of the main sources of selenium in the diet. Thus, inorganic selenium uptake and its transformation in different species were evaluated in Indian mustard (Brassica juncea), sunflower (Helianthus annus), and white lupine (Lupinus albus). More than 1.2 g kg-1 (dry matter) of Se was found in the aerial part of Indian mustard when growing on 1 mg L-1 of Se as Na2SeO4, and approximately half this amount was determined in the leaves of the lupine, which is still quite high. Selenomethionine was the main selenium-containing amino acid identified in most of the extracts by HPLC-ICP-MS. The higher values were 6.8 and 14.5 mg kg-1 (expressed as Se in dry matter) in the leaves of lupine and sunflower, respectively. This is of great importance because some authors have considered the combination of this enriched material with non-enriched food as a source of selenium supple...
100 citations
TL;DR: In this paper, the electrothermal atomic absorption spectrometric determination of selenium, cadmium and lead in different types of baby foods using slurried samples is described.
100 citations