Topic
Selenium
About: Selenium is a research topic. Over the lifetime, 21192 publications have been published within this topic receiving 429715 citations. The topic is also known as: Se & selen.
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TL;DR: The anticarcinogenic effects of selenium compounds constitute intermediate mechanisms with several underlying chemical/biochemical mechanisms such as redox cycling, alteration of protein-thiol redox status and methionine mimicry.
Abstract: Purpose of reviewTo discuss recent research related to anticarcinogenic mechanisms of selenium action in light of the underlying chemical/biochemical functions of the selenium species, likely to be executors of those effects.Recent findingsRecent studies in a variety of model systems have increased
203 citations
TL;DR: Chicks fed a diet containing torula yeast developed exudative diathesis which could be prevented by either vit.
Abstract: Summary(1) Chicks fed a diet containing torula yeast developed exudative diathesis which could be prevented by either vit. E or a non-fat soluble substance in casein and in a number of pork tissues. (2) This factor could be made water soluble by acid hydrolysis. It was adsorbed on both anion and cation exchange resins and thus behaved as an ampholyte. (3) An alkaline ash but not an acid ash of pork kidney was effective in preventing exudative diathesis. (4) Selenium as selenite prevented exudative diathesis at 0.3 ppm. Tellurium as tellurite was ineffective at 3 ppm. Anionic arsenic at 10 ppm was inactive.
202 citations
TL;DR: The concentrations of copper, manganese, selenium, and zinc were determined in the serum of 137 healthy children and in the plasma of 68 blood-donors, an important pre-requisite for diagnosis and therapy of trace element deficiencies in all age groups.
202 citations
TL;DR: Normal diploid fibroblasts were less sensitive than the cancer cell lines to the growth inhibitory effects of selenomethionine, demonstrating the differential sensitivity of tumor cells and normal cells to selenometrichionines.
202 citations
TL;DR: In this paper, the photocatalytic reduction of selenium anions, selenate (Se(VI)) and selenite (Se-IV) to elemental seenium (Se) over UV-illuminated TiO2 was performed using formic acid, acetic acid, methanol, ethanol, sucrose and salicylic acid as the organic hole scavengers.
Abstract: The photocatalytic reduction of selenium anions, selenate (Se(VI)) and selenite (Se(IV)) to elemental selenium (Se) over UV-illuminated TiO2 was performed using formic acid, acetic acid, methanol, ethanol, sucrose and salicylic acid as the organic hole scavengers. Photoreduction was only observed in the presence of formic acid, methanol or ethanol. The fastest rate of Se ions photoreduction was observed in the presence of formic acid followed by methanol and ethanol. This was attributed to the ability of formate ions to adsorb onto TiO2 in the presence of Se ions, its fast mineralisation rate and its ability to form reducing radicals quickly. For the methanol and ethanol systems, these two organic compounds could not compete with Se ions for the TiO2 surface and were not easily mineralised. The photocatalytic reduction of Se ions observed in the presence of these two organic compounds was attributed to their ability to form reducing radicals. When formic acid was used, optimum pH values at pH 3.5 and 4.0 was encountered for the Se(VI) and Se(IV) photoreduction, respectively. When methanol and ethanol were used as the hole scavenger in the pH range of 2.2–4.0, the greatest extent of Se ions photoreduction was encountered at pH 2.2. This suggests the different role of formic acid and methanol/ethanol in the photoreduction of Se ions.
200 citations