Topic
Self-healing hydrogels
About: Self-healing hydrogels is a research topic. Over the lifetime, 34980 publications have been published within this topic receiving 1259816 citations.
Papers published on a yearly basis
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TL;DR: It is timely to summarize the polymeric systems that undergo sol-gel transitions, particularly due to temperature, with emphasis on the underlying transition mechanisms and potential delivery aspects.
2,048 citations
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TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
2,034 citations
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TL;DR: The fabrication of active hydrogel components inside microchannels via direct photopatterning of a liquid phase greatly simplifies system construction and assembly as the functional components are fabricated in situ, and the stimuli-responsive hydrogels components perform both sensing and actuation functions.
Abstract: Hydrogels have been developed to respond to a wide variety of stimuli, but their use in macroscopic systems has been hindered by slow response times (diffusion being the rate-limiting factor governing the swelling process) However, there are many natural examples of chemically driven actuation that rely on short diffusion paths to produce a rapid response It is therefore expected that scaling down hydrogel objects to the micrometre scale should greatly improve response times At these scales, stimuli-responsive hydrogels could enhance the capabilities of microfluidic systems by allowing self-regulated flow control Here we report the fabrication of active hydrogel components inside microchannels via direct photopatterning of a liquid phase Our approach greatly simplifies system construction and assembly as the functional components are fabricated in situ, and the stimuli-responsive hydrogel components perform both sensing and actuation functions We demonstrate significantly improved response times (less than 10 seconds) in hydrogel valves capable of autonomous control of local flow
1,968 citations
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TL;DR: This review presents a critical analysis of covalently and ionically crosslinked chitosan hydrogels and related networks for medical or pharmaceutical applications and discusses with reference to the specific chemical interactions, which dictate gel formation.
1,930 citations
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TL;DR: GelMA hydrogels could be useful for creating complex, cell- responsive microtissues, such as endothelialized microvasculature, or for other applications that require cell-responsive microengineered hydrogELs.
1,871 citations