Semantic similarity

About: Semantic similarity is a research topic. Over the lifetime, 14605 publications have been published within this topic receiving 364659 citations. The topic is also known as: semantic relatedness.

PWCDA: Path Weighted Method for Predicting circRNA-Disease Associations

Abstract: CircRNAs have particular biological structure and have proven to play important roles in diseases. It is time-consuming and costly to identify circRNA-disease associations by biological experiments. Therefore, it is appealing to develop computational methods for predicting circRNA-disease associations. In this study, we propose a new computational path weighted method for predicting circRNA-disease associations. Firstly, we calculate the functional similarity scores of diseases based on disease-related gene annotations and the semantic similarity scores of circRNAs based on circRNA-related gene ontology, respectively. To address missing similarity scores of diseases and circRNAs, we calculate the Gaussian Interaction Profile (GIP) kernel similarity scores for diseases and circRNAs, respectively, based on the circRNA-disease associations downloaded from circR2Disease database (http://bioinfo.snnu.edu.cn/CircR2Disease/). Then, we integrate disease functional similarity scores and circRNA semantic similarity scores with their related GIP kernel similarity scores to construct a heterogeneous network made up of three sub-networks: disease similarity network, circRNA similarity network and circRNA-disease association network. Finally, we compute an association score for each circRNA-disease pair based on paths connecting them in the heterogeneous network to determine whether this circRNA-disease pair is associated. We adopt leave one out cross validation (LOOCV) and five-fold cross validations to evaluate the performance of our proposed method. In addition, three common diseases, Breast Cancer, Gastric Cancer and Colorectal Cancer, are used for case studies. Experimental results illustrate the reliability and usefulness of our computational method in terms of different validation measures, which indicates PWCDA can effectively predict potential circRNA-disease associations.

Context-sensitive semantic query expansion

Abstract: Modern information retrieval systems match the terms included in a user's query with available documents, through the use of an index. A fuzzy thesaurus is used to enrich the query with associated terms. In this work, we use semantic entities, rather than terms; this allows us to use knowledge stored in a semantic encyclopedia, specifically the ordering relations, in order to perform a semantic expansion of the query. The process of query expansion takes into account the query context, which is defined as a fuzzy set of semantic entities. Furthermore, we integrate our approach with the user's profile.

Specialising Word Vectors for Lexical Entailment

Abstract: We present LEAR (Lexical Entailment Attract-Repel), a novel post-processing method that transforms any input word vector space to emphasise the asymmetric relation of lexical entailment (LE), also known as the IS-A or hyponymy-hypernymy relation. By injecting external linguistic constraints (e.g., WordNet links) into the initial vector space, the LE specialisation procedure brings true hyponymy-hypernymy pairs closer together in the transformed Euclidean space. The proposed asymmetric distance measure adjusts the norms of word vectors to reflect the actual WordNet-style hierarchy of concepts. Simultaneously, a joint objective enforces semantic similarity using the symmetric cosine distance, yielding a vector space specialised for both lexical relations at once. LEAR specialisation achieves state-of-the-art performance in the tasks of hypernymy directionality, hypernymy detection, and graded lexical entailment, demonstrating the effectiveness and robustness of the proposed asymmetric specialisation model.

Tag-Aware Personalized Recommendation Using a Deep-Semantic Similarity Model with Negative Sampling

Abstract: With the rapid growth of social tagging systems, many efforts have been put on tag-aware personalized recommendation. However, due to uncontrolled vocabularies, social tags are usually redundant, sparse, and ambiguous. In this paper, we propose a deep neural network approach to solve this problem by mapping both the tag-based user and item profiles to an abstract deep feature space, where the deep-semantic similarities between users and their target items (resp., irrelevant items) are maximized (resp., minimized). Due to huge numbers of online items, the training of this model is usually computationally expensive in the real-world context. Therefore, we introduce negative sampling, which significantly increases the model's training efficiency (109.6 times quicker) and ensures the scalability in practice. Experimental results show that our model can significantly outperform the state-of-the-art baselines in tag-aware personalized recommendation: e.g., its mean reciprocal rank is between 5.7 and 16.5 times better than the baselines.