Topic
Semen
About: Semen is a research topic. Over the lifetime, 14571 publications have been published within this topic receiving 407739 citations. The topic is also known as: come & ejaculate.
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01 Jan 1976
TL;DR: The role of semen and fertility regulation in men and women's sexual activity and sexual activity is studied in more detail in this chapter.
Abstract: Human semen and fertility regulation in men , Human semen and fertility regulation in men , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
244 citations
TL;DR: Low-density lipoproteins preserve bull semen quality and fertilizing ability, allowing also better semen motility, after the freeze-thaw process, in conclusion.
244 citations
TL;DR: This study found an average volume of ejaculate and an average sperm concentration that are considerably lower than in the earlier studies reported, and it is suggested that studies be undertaken to determine whether some factor has significantly altered or influenced the male potential fertility rate.
244 citations
TL;DR: Work in the laboratory indicated that treatment with 10 per cent glycerol prior to freezing with ‘dry ice’ produced an average 67 per cent survival of human spermatozoa obtained from five young healthy men.
Abstract: MONTEGAZZA1 observed the survival of human spermatozoa after exposure to a temperature of − 15° C. He speculated that in the future, frozen semen might be used in animal husbandry and even proposed that a man dying on the battlefield might, by his wife, beget a legitimate child after his own death. Other workers2 have reported the survival of human spermatozoa; however, it was not until Polge, Smith and Parkes3 reported increased survival of frozen human spermatozoa employing glycerol as a protective agent that practical application seemed possible. Work in our laboratory4, recently, indicated that treatment with 10 per cent glycerol prior to freezing with ‘dry ice’ produced an average 67 per cent survival of human spermatozoa obtained from five young healthy men.
241 citations
TL;DR: The cytogenetic data show significantly elevated frequencies of diploidy, autosomal disomy and nullisomy, sex chromosome aneuploidsy, and total aneuPLoidy in OAT patients, which may contribute to the patients' infertility.
Abstract: Recent evidence suggests that infertile males donating semen for intracytoplasmic sperm injection (ICSI) may be at an increased risk of transmitting numerical (predominantly sex chromosome) abnormalities to their offspring. The present study was designed to determine aneuploidy in spermatozoa from oligoasthenoteratozoospermic (OAT) patients undergoing ICSI. Aneuploidy frequencies of 12 autosomes and the sex chromosomes were determined by fluorescence in-situ hybridization (FISH) on spermatozoa from fresh ejaculate of nine severe OAT patients and four proven fertile donors. FISH, using directly labelled (fluorochrome-dUTP) satellite or contig DNA probes specific for chromosomes 4, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 21, X, and Y, was performed on decondensed spermatozoa. Per chromosome disomy frequencies for autosomes and sex chomosomes in OAT males were 0-5. 4%. In contrast, the disomy frequencies in controls were 0.05-0.2%. The frequency of diploid spermatozoa in OAT patients was 0.4-9.6%; controls showed a mean of 0.04%. Using recently developed formulae, the total aneuploidy in our OAT patient population was estimated to be 33-74%. In contrast, estimates of mean total aneuploidy in the spermatozoa of controls ranged from 4.1 to 7.7%, depending upon method of calculation. Six series of ICSI were performed on five of the OAT patients. Four resulted in no establishment of pregnancy; the others failed to establish ongoing pregnancies. Our cytogenetic data show significantly elevated frequencies of diploidy, autosomal disomy and nullisomy, sex chromosome aneuploidy, and total aneuploidy in OAT patients, which may contribute to the patients' infertility.
241 citations