Showing papers on "Semen analysis published in 1977"

Studies of human semen in topical corticosteroid-treated and in methotrexate-treated psoriatics.

Abstract: Ejaculates were studied from ten men with severa psoriasis treated with topical corticosteroids and from ten similar patients who had received methotrexate therapy from 1 to 9 years. It was not possible to demonstrate any unfavorable effect on the semen quality during the methotrexate therapy. The semen analysis was more frequently found normal (p = 0.04) in the methotrexate treated group, and no specific abnormality was found in spermatozoa of methotrexate-treated patients. Methotrexate therapy to male psoriatics seems safe and in agreement with this no congenital abnormalities have been reported. A remarkable number of the ejaculates had reduced sperm qualities, and it is proposed that this might be due to psoriatic lesions in the genital tract.

The effect of temperature on the motility and viability of sperm.

Abstract: In specimens of semen kept at 37 degrees C sperm lose their motility and viability. If kept at 4 degrees C they retain their viability but lose their motility from so-called thermal shock. The best temperature to keep semen in order to preserve sperm motility is 20 degrees C. Loss of motility at 37 degrees C is not entirely prevented by prevention of bacterial contamination with antibiotics.

Techniques of artificial insemination.

Abstract: The guidelines and practices of the artificial insemination program at the University of Oregon Health Sciences Center is reviewed. Donor seman for the sperm bank is analyzed for sperm count volume motility and ability to withstand freezing. The donor is checked for venereal disease general health and genetic history. It is generally thought that fresh sperm have a higher success rate; 80% of insemination specimens used are fresh. In every couple considering artificial insemination evaluation is made of both female and male subfertility factors. In semen analysis the most important criterion is motility which should be above 50%. 20% or less of abnormal forms is acceptable. A routine linear cervical mucus penetration test is planned. A minimum of 2 semen samples are analyzed taken 1 month apart; and a questionnaire concerning sexual practices and history completed. A serum prolactin is obtained for patients with low sperm count; a thorough urologic examination is mandatory for oligospermic men. Artificial insemination with husband semen is useful in some circumstances; artificial insemination with donor serum is the choice in azoospermia with a serious inheritable disease in which the husband is a carrier or victim and when the wife has a history of infants affected with erythroblastosis fetalis.

Seminal fructose, citric acid and phosphatase levels and their relation to the sperm count in man.

Abstract: Seminal fructose, citric acid and phosphatase levels were estimated in 60 normal adults and compared with 60 oligospermic and 24 azoospermic Indian subjects. In normal group, the seminal plasma fructose level and acid phosphatase activity showed a fall as the sperm count increased. As compared to normals, significantly higher mean values for fructose and acid phosphatase activity were observed in oligospermic and azoospermic groups. Seminal alkaline phosphatase activity did not show any relationship with sperm count. Similarity in changes observed in seminal fructose and acid phosphatase levels with respect to seminal citric acid content and sperm concentration suggests that both these parameters are probably regulated by similar physiological mechanism.

The immunological analysis of semen.

Abstract: Semen from men attending a subfertility clinic and a post-vasectomy clinic has been studied by immunodiffusion using polyvalent and monospecific antisera. In total, semen samples from 277 men have been studied and a ‘normal profile’ of seminal proteins established. There are no obvious differences in the semen samples from these two different populations. The majority of proteins studied are unlikely to be useful for discriminating between semen samples in medicolegal enquiries.

Evaluation of the impairment of spermatogenesis in varicocele through semen analysis and testicular biopsy

Abstract: Twenty-four patients with varicocele and 26 normal men were analysed according to the seminal ejaculate and testicular biopsy. Patients were divided into two groups based on the criteria of sperm normality and abnormality, respectively.

Sperm preservation for young cancer patients

Abstract: Use of sperm banks is indicated in young men with any type of cancer involving radiotherapy or chemotherapy, because significant amounts of the X-ray dose may reach the testes, and antimitotic drugs may affect spermatogenesis. The most common indications are seminomas, carcinomas, choriocarcinomas, or teratomas of the testicle and hematosarcomas such as Hodgkin's disease, as well as other conditions treated with antimitotics like autoimmune disease and immunosuppression before grafting. The authors were consulted by 22 patients, 8 with testicular cancer and 14 with Hodgkin's disease; only 9 were seen before treatment, and only 5 benefited by sperm bank. The protocol followed was a series of 3 sperm counts and motility readings on the 1st part of a split ejaculate, then a congelation test if indicated, each sample separated by at least 3 1/2 days of abstinence. Therefore the whole series usually took 2 weeks, requiring that chemotherapy be postponed for a while after orchidectomy, so that a period between treatments be available. If sperm preservation is considered after the beginning of treatment, there is no way of detecting the effect on spermatogenesis or on mutation. For pregnancies conceived after such treatment, amniocentesis is advised to screen for chromosoamal anomalies. Vasectomy is suggested in cases of familial cancers.