Topic
Semen analysis
About: Semen analysis is a research topic. Over the lifetime, 4909 publications have been published within this topic receiving 143225 citations.
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TL;DR: This review focuses on the state of the art of ICSI regarding utility of bioassays that evaluate male factor infertility beyond the standard semen analysis and describes the current application and advances in regard to ICSi, particularly the genetic and epigenetic characteristics of spermatozoa and their impact on reproductive outcome.
Abstract: Among infertile couples, 25% involve both male and female factors, while male factor alone accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the three, or even a complete absence of sperm cells in the ejaculate and can lead to a poor prognosis even with the help of assisted reproductive technology (ART). Intracytoplasmic sperm injection (ICSI) has been with us now for a quarter of a century and in spite of the controversy generated since its inception, it remains in the forefront of the techniques utilized in ART. The development of ICSI in 1992 has drastically decreased the impact of male factor, resulting in millions of pregnancies worldwide for couples who, without ICSI, would have had little chance of having their own biological child. This review focuses on the state of the art of ICSI regarding utility of bioassays that evaluate male factor infertility beyond the standard semen analysis and describes the current application and advances in regard to ICSI, particularly the genetic and epigenetic characteristics of spermatozoa and their impact on reproductive outcome.
79 citations
TL;DR: Results from this controlled, randomized clinical trial show that FSH therapy does not improve sperm concentration or pregnancy rate when infertile male patients are chosen solely by the clinical criteria of idiopathic oligospermia and normal FSH concentration.
79 citations
TL;DR: Cigarette smoking and alcohol consumption separately and combined were found to have deleterious effect on sperm parameters and SDF and it is suggested that both habits may contribute to infertility problems.
Abstract: Both cigarette smoking and alcohol consumption are somehow implicated in sperm function, but the impact of these two lifestyle factors on sperm parameters remains controversial. The present study is focused on the impact of cigarette smoking and alcohol consumption separately and combined on sperm parameters and sperm DNA fragmentation (SDF). The study included 207 consecutive semen samples derived from men who were seeking semen analysis for fertility purposes in our IVF Unit. Semen volume, percent of degenerated spermatozoa and SDF were significantly correlated with the various smoking status. The percent of spermatozoa with small halos significantly correlated with the alcohol status. The smoking status of the men was correlated with the alcohol status. Cigarette smoking and alcohol consumption separately and combined were found to have deleterious effect on sperm parameters and SDF. It is suggested that both habits may contribute to infertility problems.
79 citations
TL;DR: Fertility/subfertility thresholds of <5% normal sperm morphology, a concentration <15 × 106/ml, and a motility <30% should be used to identify the subfertile male, which fits in vitro fertilization and intrauterine insemination data calculated previously.
Abstract: Aims: To present a structured review of the literature published on semen parameters and in vivo fertility potential and to establish fertility/subfertility thresholds for sperm mor
79 citations
TL;DR: Routine sperm banking should be recommended for men with a diagnosis of testicular cancer to preserve future fertility potential, and the effects of cryopreservation were not significantly affected by histologic features or stage.
79 citations