Topic
Serum albumin
About: Serum albumin is a research topic. Over the lifetime, 16337 publications have been published within this topic receiving 516395 citations. The topic is also known as: blood albumin & ANALBA.
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TL;DR: The large number of observed bands suggests that slight variations in helical geometry, symmetry, or interactions result in changed amide III frequencies, so that simple correlations between narrow frequency ranges and secondary structures may not be applicable for this mode.
133 citations
133 citations
TL;DR: It is shown that at micromolar cerebrospinal fluid levels, HSA inhibits the kinetics of Aβ fibrillization, significantly increasing the lag time and decreasing the total amount of fibrils produced.
133 citations
TL;DR: The English literature on the prognostic value of pretreatment albumin levels in colorectal cancer is reviewed and evidence is consolidated that led to the current understanding of hypoalbuminemia as an inflammatory marker rather than as a nutritional one among patients with coloreCTal cancer.
Abstract: Albumin is the single most abundant protein in the human serum. Its roles in physiology and pathology are diverse. Serum albumin levels have been classically thought to reflect the nutritional status of patients. This concept has been challenged in the last two decades as multiple factors, such as inflammation, appeared to affect albumin levels independent of nutrition. In general, cancer patients have a high prevalence of hypoalbuminemia. As such, the role of hypoalbuminemia in patients with colorectal cancer has received significant interest. We reviewed the English literature on the prognostic value of pretreatment albumin levels in colorectal cancer. We also consolidated the evidence that led to the current understanding of hypoalbuminemia as an inflammatory marker rather than as a nutritional one among patients with colorectal cancer.
133 citations
TL;DR: In this paper, the degradation of copoly(L-lactic acid-boxyethylene-b-L- lactic acid) (LPLA-PEO-LPLA) showed striking differences compared to the respective homo- or co-polymers.
133 citations