Topic
Serum albumin
About: Serum albumin is a research topic. Over the lifetime, 16337 publications have been published within this topic receiving 516395 citations. The topic is also known as: blood albumin & ANALBA.
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TL;DR: The greater degree of fluorescence enhancement, the greater stability ofretinol in RBP and PA-RBP to spontaneous degradation at room temperature, the relative resistance to extraction of the bound retinol by ether, and the complete unavailability of the retinols inRBP andPA-R BP for oxidation by liver alcohol dehydrogenase were interpreted as indicating that retinOL is bound with greater affinity to the natural carrier protein than it is to bovine serum albumin or
234 citations
233 citations
Journal Article•
TL;DR: It is concluded that nutritional status may represent a major determinant of survival in AIDS and the rate of albumin decrease may define a function limiting survival of individual patients with AIDS.
233 citations
TL;DR: Radiolysis of bovine serum albumin under aerobic and anaerobic conditions was studied by SDS-polyacrylamide gel electrophoresis and the radiation-induced broadening of the serumalbumin peak is interpreted as being a result of intramolecular disulfide exchange.
Abstract: Radiolysis of bovine serum albumin under aerobic and anaerobic conditions was studied by SDS-polyacrylamide gel electrophoresis. After Coomassie Blue or Fast Green staining quantitative evaluations give information about the degradation processes of the protein. Under nitrogen the main reaction is the aggregation caused by covalent cross-links, which includes only a small portion of intermolecular S-S bridges. Under air the radiolysis leads to peptide chain scission, which is not a random process, but yields specific protein fragments. A mechanism for this fragmentation reaction is suggested. The radiation-induced broadening of the serum albumin peak is interpreted as being a result of intramolecular disulfide exchange. In contrast to lactate dehydrogenase the degradation of serum albumin is enhanced by oxygen, probably because of its low tryptophan content.
232 citations
TL;DR: With this assay, Lipidex 1000 appeared to be useful for the delipidation of protein samples at 37 degrees C and for a radiochemical assay of fatty acid-binding by microgram amounts of protein at 0 degree C.
230 citations